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The map label for this gene is cadC [H]

Identifier: 148550740

GI number: 148550740

Start: 202186

End: 203334

Strand: Direct

Name: cadC [H]

Synonym: Swit_5304

Alternate gene names: 148550740

Gene position: 202186-203334 (Clockwise)

Preceding gene: 148550736

Following gene: 148550741

Centisome position: 65.17

GC content: 69.45

Gene sequence:

>1149_bases
GTGCCGCCGCGTGGATATCATTTCGGCCAGTTCGTCCTCGATCCCGAGGATCGGCGCCTGCTGCGTGACGGCGTTCCGGT
CGAGCTCAACGCGCGCTATCTCGACGCGCTGGCGCTTCTCGTGCGCAATGCCGGGTCGCTCGTCGGCAAGGACCGTTTTC
TAAGTGAAGTCTGGAAAGATGTGCCTGTCACCGACGAGGCGCTGACCCAGTGCATCCGGCTCCTTCGCCAGCGTCTGGGT
GACGATGCGAGCCGTCCGCATTTCATCGAAACGGTACCCAAGCATGGCTACCGCTTCATTGCCGAGGTCGACTGGCGCGA
AAGCTCTGCCCCGGCCGAAGACGCGGCCCCCCACACGCTTCCCCCGTCGGCCGCGCCCTCGGCGCTCCGCCGCGTAGCGA
TGATGGCGGGAGCCGGGACCCTGGGTGCTGGGGGCGCCGGATTGATCGGCGGGCTCGCATACGGCTTTATCGCCGCGACG
CCGCCGCTCCCGAGCGGAGGCGGCGCCGCGTCCTCCGTCTTCGTGTTGCTCTGGCTCACCCTGGCGGTGGCGCTCGTGGG
CGGCGCGGGCGTCAGCCTGGGGATTGCCATAGCCGAGGCCGCAGGCAAACGCCCATGGCTCACTCCTGGCGGCGCAGTCG
GCGGAATGATCGTCGGCGCCGTCGTGAAGTTGCTCGGGATCGACGCGTTCAATCTCCTGTTCGGCCAGTCACCGACAGGG
ATTACGGGCGGGCTCGAAGGGCTTTTCCTGGGGGCCGGCGTGGGCCTTGGCGCGACCCTGTCCGGCATGGGCGGCTCGGA
TCGTTCCCTTCGCTCTGTGGCAGCGCGGGCGGCGCTTTGCGGCGGTGCGGCCGGGAGCGTTGTCGTTCTTCTTGGCGGCC
ACCTGCTGGCGGGGAGCTTCGAGCAACTCGTCCAGACATTCCCGCAATCGCGGATCGGCCTTGCGCAGATCGGCGGCCTG
TTCGGCGAGCAGGGTCTTGGACCGGTGGCCGAGGCGGCCTGCGCGTTCGGCGAAGGGGCGCTGTTCGCGGCGGGCGTGGT
CGTTGCCATGACGCTCGCGCGCCGTGAGATGGACAGGCCTGAAGGCCGCTCGGCGGCGTCGTCCGGCCTGGTTGCGAGTC
GCAGAGGCGGCGCGCCTCGGTTGGGCTAG

Upstream 100 bases:

>100_bases
CGATGATCATCCATGATATCGCCTCCATTCGAGATGAGATCATCAGGGTCCCGGAAAGACCGATGAGCGTCATGAGAAGC
ATATGAGGTTTTGCTGAAAA

Downstream 100 bases:

>100_bases
GACCCGCCAGCCCGAAGCATGGGCGGTGGAGCGCCGCCGGTCGCGTCGTTCCGGCTATCATTGACCGTCTAAATCGTCAG
GCCTGCATGTTGCGGGAGGC

Product: transcriptional regulator, CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MPPRGYHFGQFVLDPEDRRLLRDGVPVELNARYLDALALLVRNAGSLVGKDRFLSEVWKDVPVTDEALTQCIRLLRQRLG
DDASRPHFIETVPKHGYRFIAEVDWRESSAPAEDAAPHTLPPSAAPSALRRVAMMAGAGTLGAGGAGLIGGLAYGFIAAT
PPLPSGGGAASSVFVLLWLTLAVALVGGAGVSLGIAIAEAAGKRPWLTPGGAVGGMIVGAVVKLLGIDAFNLLFGQSPTG
ITGGLEGLFLGAGVGLGATLSGMGGSDRSLRSVAARAALCGGAAGSVVVLLGGHLLAGSFEQLVQTFPQSRIGLAQIGGL
FGEQGLGPVAEAACAFGEGALFAAGVVVAMTLARREMDRPEGRSAASSGLVASRRGGAPRLG

Sequences:

>Translated_382_residues
MPPRGYHFGQFVLDPEDRRLLRDGVPVELNARYLDALALLVRNAGSLVGKDRFLSEVWKDVPVTDEALTQCIRLLRQRLG
DDASRPHFIETVPKHGYRFIAEVDWRESSAPAEDAAPHTLPPSAAPSALRRVAMMAGAGTLGAGGAGLIGGLAYGFIAAT
PPLPSGGGAASSVFVLLWLTLAVALVGGAGVSLGIAIAEAAGKRPWLTPGGAVGGMIVGAVVKLLGIDAFNLLFGQSPTG
ITGGLEGLFLGAGVGLGATLSGMGGSDRSLRSVAARAALCGGAAGSVVVLLGGHLLAGSFEQLVQTFPQSRIGLAQIGGL
FGEQGLGPVAEAACAFGEGALFAAGVVVAMTLARREMDRPEGRSAASSGLVASRRGGAPRLG
>Mature_381_residues
PPRGYHFGQFVLDPEDRRLLRDGVPVELNARYLDALALLVRNAGSLVGKDRFLSEVWKDVPVTDEALTQCIRLLRQRLGD
DASRPHFIETVPKHGYRFIAEVDWRESSAPAEDAAPHTLPPSAAPSALRRVAMMAGAGTLGAGGAGLIGGLAYGFIAATP
PLPSGGGAASSVFVLLWLTLAVALVGGAGVSLGIAIAEAAGKRPWLTPGGAVGGMIVGAVVKLLGIDAFNLLFGQSPTGI
TGGLEGLFLGAGVGLGATLSGMGGSDRSLRSVAARAALCGGAAGSVVVLLGGHLLAGSFEQLVQTFPQSRIGLAQIGGLF
GEQGLGPVAEAACAFGEGALFAAGVVVAMTLARREMDRPEGRSAASSGLVASRRGGAPRLG

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: COG3710

COG function: function code K; DNA-binding winged-HTH domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=147, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 38699; Mature: 38568

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRGYHFGQFVLDPEDRRLLRDGVPVELNARYLDALALLVRNAGSLVGKDRFLSEVWKD
CCCCCCCCCCEEECCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPVTDEALTQCIRLLRQRLGDDASRPHFIETVPKHGYRFIAEVDWRESSAPAEDAAPHTL
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCC
PPSAAPSALRRVAMMAGAGTLGAGGAGLIGGLAYGFIAATPPLPSGGGAASSVFVLLWLT
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAVALVGGAGVSLGIAIAEAAGKRPWLTPGGAVGGMIVGAVVKLLGIDAFNLLFGQSPTG
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
ITGGLEGLFLGAGVGLGATLSGMGGSDRSLRSVAARAALCGGAAGSVVVLLGGHLLAGSF
CCCCHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCH
EQLVQTFPQSRIGLAQIGGLFGEQGLGPVAEAACAFGEGALFAAGVVVAMTLARREMDRP
HHHHHHCCHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
EGRSAASSGLVASRRGGAPRLG
CCCCHHHCCCEECCCCCCCCCC
>Mature Secondary Structure 
PPRGYHFGQFVLDPEDRRLLRDGVPVELNARYLDALALLVRNAGSLVGKDRFLSEVWKD
CCCCCCCCCEEECCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPVTDEALTQCIRLLRQRLGDDASRPHFIETVPKHGYRFIAEVDWRESSAPAEDAAPHTL
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCC
PPSAAPSALRRVAMMAGAGTLGAGGAGLIGGLAYGFIAATPPLPSGGGAASSVFVLLWLT
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LAVALVGGAGVSLGIAIAEAAGKRPWLTPGGAVGGMIVGAVVKLLGIDAFNLLFGQSPTG
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
ITGGLEGLFLGAGVGLGATLSGMGGSDRSLRSVAARAALCGGAAGSVVVLLGGHLLAGSF
CCCCHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCH
EQLVQTFPQSRIGLAQIGGLFGEQGLGPVAEAACAFGEGALFAAGVVVAMTLARREMDRP
HHHHHHCCHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
EGRSAASSGLVASRRGGAPRLG
CCCCHHHCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]