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The map label for this gene is yciR [C]

Identifier: 148550736

GI number: 148550736

Start: 198195

End: 200327

Strand: Direct

Name: yciR [C]

Synonym: Swit_5300

Alternate gene names: 148550736

Gene position: 198195-200327 (Clockwise)

Preceding gene: 148550735

Following gene: 148550740

Centisome position: 63.89

GC content: 64.7

Gene sequence:

>2133_bases
ATGCCCGCAGCTGTCCGTCTTCTCCGCGTTTCTGTGCCACGGCAGTATCTTTGGCCGCTCTTGTCGCTGCTTGGCGTATG
CTTCGGTTTCATCTTCCTGCTCATTTTCTTGAGTACCCGCGCACAGGATGCCCAGCAGCTCGAGCGGGAGCGCCAGGCGC
TCGGGGGCGTGTTCGCCACCGCGTCCGCGATGGTGCAGCACGATCTGCAGGATTACGCCAAATGGGACGATGCCGTGCGT
CACATCGGCTCGAGGTTCGATGCGGCCTGGATGGACGACAATGTCGTGGCCTATCTGGGCCGCACCCAGGGATATTCCGA
CATCTTCGTGCTCGGCGCGGACGATCGGACCCTTTACAGCTTTAAAGACCGGAAGAGCGCCGCGAAGACCGCTCACCTGC
GTCTTGGCGCCGACTTCGTCCGCTCGATCGCCGAAGTGCGGCGCTTGCCGCCTGAGGGCAGCCCGATCGTCAGTGGCTTC
ACGCGCTCGGGCCAGCAGATCATGGTCTATGCCACGGCCGCCGTGGTGCCCTTGACGGGTAAGATCGCGGCGCCCCGAGG
GCCGACCCGCCTTCTGGTCATCGCCCGGCACGTCGACGAGGCGTTCTTGGCGGACCTCACGCGCGAACTCAATGTCCACG
ATGTGCGGCTGACGCTTGGGAACCGGACAGCCGGAATGGACGCCATCGCCATCAAGGGCCGGTCGGGCGAACGGATCGCC
TGGCTGGAATGGCGGTCGCATCATCCGGGTGCATCGCTGAGGCAGCATCTGGTGCCGGCGATCCTGGCGGTGGCCTTCGT
CGCCTTTGTGGCAGCCGGCCTAATTCTTCGCCGGGGCGGCCAGTCGATCGAGGCTTTGCGCGCAAGCGAGCTTCTTGCCC
GGCATCTGTCGGATCACGATACCTTGACCGAACTGCCCAATCGCCGCGCGCTAGGGGAGCGGCTGGGCGAGCTTGTCGCG
GCAAGGCAAGGACTGGCCCTGCTGTTCCTCGATCTCGACGGGTTCAAGGACGCCAATGATGTCTACGGCCATAGTGCCGG
CGATCTCCTGCTCAAGGAAGCCGCCGGTCGCCTGAAGGCCGCGGCGGGAGAGGCCTTCATCGCGCGCGCGGGCGGCGACG
AGTTTGCCGTTCTCTTGAGATCGCCATCGCCTGGCGCGGCGGCCGCGACATGCGAGGCCATTCTCGAAGCGTTCTCGACG
CCCTTCAAGGTTGGCGCCTACAGCATCACGATCGGGACCAGCATCGGCTATTTCGAGACCGACACATCCTGCGACGGCGC
GGAAGAGTCCATTCGCAAGGCGGACGTCGCCATGTATGCCGCCAAGGATGCGGGCAGGCACTGCGCGCGGGTTTACCACC
CCTCGCTCGACGAAAGCCATGAACGGCGCCAGCGGCTCGAGCAGGATCTCAAGCGCGCGGTCGAGGACGAAGAGATCTAT
GTCCGCTATCAACCGATCGTCGATGCGCAGTCGGGTGAAGTCGTCGCCGTCGAGGCGCTGGCGCGCTGGTCTCATCCTGT
CCATGGCGATGTTCCGCCCGACGTGTTCATTCCGATCGCCGAAATCAGCGGGCTGATCAACGCGATCGGCCGCCAGGTGC
TTCTCCATGCGTGCCGGGAAATGCGCGAGACCGGGCTCGATCTGGCCGTCAACCTGTCGCCAGCGCAATTCTGGGATGGC
AATCTCTACGACGAGGTTCAGCAGGTCCTGGAACGGACCGGGTTTCCTCCCGAGCGGCTGGAGCTGGAAATCACGGAAAG
CTTGCTGCTGCGCCGTCCCCAGGTCGCCGCGGCGGTGATCGACCGGCTGCGCTCACTCGGTATCCGCATGGCGCTCGACG
ACTTTGGCACGGGGTTCGCGAGCATCGCCTATCTACAGCAACTCACGATCGACCGGCTCAAGATCGACAGGTCGTTCCTT
GCTCCGCTGGAATCGCAGCCTGACATGCGAGAGGTGCTGATCTCCATCGTCGGCCTGGCGAAGGCCTATCATCTTGAAGT
CTGTGCCGAAGGGATCGAGACGCCGGGACAGGCGCAGCTTGCGCGCATCGCGGGCTGCGGCCGCTTGCAAGGTTGGCTGT
TCGGGCGTCCGCAAGCCGCGAGCGCCTTCCAGCCCGTGGCCTTGCGAGCTTAG

Upstream 100 bases:

>100_bases
GCCTATGAAGAGGCCAGCGCGGCCTGATCGGTCGCGGGGAGCATCCTTTCCCGAGGCAGCCGACAGGAGAGCTTTAACCA
AGTTGCGATATCGCGAGTCC

Downstream 100 bases:

>100_bases
GAGCGCGAGGGAAGCGGTCGGCCGGTCAACGACCGCGCCGATCCTGCGGAACGATCATGGCCGAACGACGGGCGAGCAAT
GGGCCGCCTCGATGCGCCAC

Product: periplasmic sensor diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MPAAVRLLRVSVPRQYLWPLLSLLGVCFGFIFLLIFLSTRAQDAQQLERERQALGGVFATASAMVQHDLQDYAKWDDAVR
HIGSRFDAAWMDDNVVAYLGRTQGYSDIFVLGADDRTLYSFKDRKSAAKTAHLRLGADFVRSIAEVRRLPPEGSPIVSGF
TRSGQQIMVYATAAVVPLTGKIAAPRGPTRLLVIARHVDEAFLADLTRELNVHDVRLTLGNRTAGMDAIAIKGRSGERIA
WLEWRSHHPGASLRQHLVPAILAVAFVAFVAAGLILRRGGQSIEALRASELLARHLSDHDTLTELPNRRALGERLGELVA
ARQGLALLFLDLDGFKDANDVYGHSAGDLLLKEAAGRLKAAAGEAFIARAGGDEFAVLLRSPSPGAAAATCEAILEAFST
PFKVGAYSITIGTSIGYFETDTSCDGAEESIRKADVAMYAAKDAGRHCARVYHPSLDESHERRQRLEQDLKRAVEDEEIY
VRYQPIVDAQSGEVVAVEALARWSHPVHGDVPPDVFIPIAEISGLINAIGRQVLLHACREMRETGLDLAVNLSPAQFWDG
NLYDEVQQVLERTGFPPERLELEITESLLLRRPQVAAAVIDRLRSLGIRMALDDFGTGFASIAYLQQLTIDRLKIDRSFL
APLESQPDMREVLISIVGLAKAYHLEVCAEGIETPGQAQLARIAGCGRLQGWLFGRPQAASAFQPVALRA

Sequences:

>Translated_710_residues
MPAAVRLLRVSVPRQYLWPLLSLLGVCFGFIFLLIFLSTRAQDAQQLERERQALGGVFATASAMVQHDLQDYAKWDDAVR
HIGSRFDAAWMDDNVVAYLGRTQGYSDIFVLGADDRTLYSFKDRKSAAKTAHLRLGADFVRSIAEVRRLPPEGSPIVSGF
TRSGQQIMVYATAAVVPLTGKIAAPRGPTRLLVIARHVDEAFLADLTRELNVHDVRLTLGNRTAGMDAIAIKGRSGERIA
WLEWRSHHPGASLRQHLVPAILAVAFVAFVAAGLILRRGGQSIEALRASELLARHLSDHDTLTELPNRRALGERLGELVA
ARQGLALLFLDLDGFKDANDVYGHSAGDLLLKEAAGRLKAAAGEAFIARAGGDEFAVLLRSPSPGAAAATCEAILEAFST
PFKVGAYSITIGTSIGYFETDTSCDGAEESIRKADVAMYAAKDAGRHCARVYHPSLDESHERRQRLEQDLKRAVEDEEIY
VRYQPIVDAQSGEVVAVEALARWSHPVHGDVPPDVFIPIAEISGLINAIGRQVLLHACREMRETGLDLAVNLSPAQFWDG
NLYDEVQQVLERTGFPPERLELEITESLLLRRPQVAAAVIDRLRSLGIRMALDDFGTGFASIAYLQQLTIDRLKIDRSFL
APLESQPDMREVLISIVGLAKAYHLEVCAEGIETPGQAQLARIAGCGRLQGWLFGRPQAASAFQPVALRA
>Mature_709_residues
PAAVRLLRVSVPRQYLWPLLSLLGVCFGFIFLLIFLSTRAQDAQQLERERQALGGVFATASAMVQHDLQDYAKWDDAVRH
IGSRFDAAWMDDNVVAYLGRTQGYSDIFVLGADDRTLYSFKDRKSAAKTAHLRLGADFVRSIAEVRRLPPEGSPIVSGFT
RSGQQIMVYATAAVVPLTGKIAAPRGPTRLLVIARHVDEAFLADLTRELNVHDVRLTLGNRTAGMDAIAIKGRSGERIAW
LEWRSHHPGASLRQHLVPAILAVAFVAFVAAGLILRRGGQSIEALRASELLARHLSDHDTLTELPNRRALGERLGELVAA
RQGLALLFLDLDGFKDANDVYGHSAGDLLLKEAAGRLKAAAGEAFIARAGGDEFAVLLRSPSPGAAAATCEAILEAFSTP
FKVGAYSITIGTSIGYFETDTSCDGAEESIRKADVAMYAAKDAGRHCARVYHPSLDESHERRQRLEQDLKRAVEDEEIYV
RYQPIVDAQSGEVVAVEALARWSHPVHGDVPPDVFIPIAEISGLINAIGRQVLLHACREMRETGLDLAVNLSPAQFWDGN
LYDEVQQVLERTGFPPERLELEITESLLLRRPQVAAAVIDRLRSLGIRMALDDFGTGFASIAYLQQLTIDRLKIDRSFLA
PLESQPDMREVLISIVGLAKAYHLEVCAEGIETPGQAQLARIAGCGRLQGWLFGRPQAASAFQPVALRA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=434, Percent_Identity=35.4838709677419, Blast_Score=259, Evalue=5e-70,
Organism=Escherichia coli, GI87081921, Length=414, Percent_Identity=29.7101449275362, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI226510982, Length=433, Percent_Identity=31.1778290993072, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=34.136546184739, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI1786507, Length=257, Percent_Identity=33.0739299610895, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=33.75, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=32.5396825396825, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=30.9917355371901, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081980, Length=245, Percent_Identity=33.0612244897959, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1787055, Length=244, Percent_Identity=29.9180327868852, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1788849, Length=410, Percent_Identity=26.8292682926829, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788381, Length=392, Percent_Identity=27.8061224489796, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082096, Length=417, Percent_Identity=27.0983213429257, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081977, Length=181, Percent_Identity=33.7016574585635, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788956, Length=150, Percent_Identity=40.6666666666667, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI87082007, Length=157, Percent_Identity=37.5796178343949, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787802, Length=158, Percent_Identity=32.2784810126582, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081881, Length=158, Percent_Identity=32.9113924050633, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI145693134, Length=174, Percent_Identity=32.7586206896552, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=30.1775147928994, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87082280, Length=219, Percent_Identity=26.9406392694064, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1786584, Length=162, Percent_Identity=32.0987654320988, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787410, Length=219, Percent_Identity=26.027397260274, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=30.379746835443, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 77678; Mature: 77547

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAVRLLRVSVPRQYLWPLLSLLGVCFGFIFLLIFLSTRAQDAQQLERERQALGGVFAT
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ASAMVQHDLQDYAKWDDAVRHIGSRFDAAWMDDNVVAYLGRTQGYSDIFVLGADDRTLYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEH
FKDRKSAAKTAHLRLGADFVRSIAEVRRLPPEGSPIVSGFTRSGQQIMVYATAAVVPLTG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEEEEEEECCC
KIAAPRGPTRLLVIARHVDEAFLADLTRELNVHDVRLTLGNRTAGMDAIAIKGRSGERIA
CEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCEEE
WLEWRSHHPGASLRQHLVPAILAVAFVAFVAAGLILRRGGQSIEALRASELLARHLSDHD
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
TLTELPNRRALGERLGELVAARQGLALLFLDLDGFKDANDVYGHSAGDLLLKEAAGRLKA
HHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHH
AAGEAFIARAGGDEFAVLLRSPSPGAAAATCEAILEAFSTPFKVGAYSITIGTSIGYFET
HCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEC
DTSCDGAEESIRKADVAMYAAKDAGRHCARVYHPSLDESHERRQRLEQDLKRAVEDEEIY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEE
VRYQPIVDAQSGEVVAVEALARWSHPVHGDVPPDVFIPIAEISGLINAIGRQVLLHACRE
EEEECCEECCCCCEEEHHHHHHCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
MRETGLDLAVNLSPAQFWDGNLYDEVQQVLERTGFPPERLELEITESLLLRRPQVAAAVI
HHHCCCCEEEECCCHHCCCCCHHHHHHHHHHHCCCCHHHEEHHHHHHHHHCCCHHHHHHH
DRLRSLGIRMALDDFGTGFASIAYLQQLTIDRLKIDRSFLAPLESQPDMREVLISIVGLA
HHHHHCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHH
KAYHLEVCAEGIETPGQAQLARIAGCGRLQGWLFGRPQAASAFQPVALRA
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PAAVRLLRVSVPRQYLWPLLSLLGVCFGFIFLLIFLSTRAQDAQQLERERQALGGVFAT
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ASAMVQHDLQDYAKWDDAVRHIGSRFDAAWMDDNVVAYLGRTQGYSDIFVLGADDRTLYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEH
FKDRKSAAKTAHLRLGADFVRSIAEVRRLPPEGSPIVSGFTRSGQQIMVYATAAVVPLTG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEEEEEEECCC
KIAAPRGPTRLLVIARHVDEAFLADLTRELNVHDVRLTLGNRTAGMDAIAIKGRSGERIA
CEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCEEE
WLEWRSHHPGASLRQHLVPAILAVAFVAFVAAGLILRRGGQSIEALRASELLARHLSDHD
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
TLTELPNRRALGERLGELVAARQGLALLFLDLDGFKDANDVYGHSAGDLLLKEAAGRLKA
HHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHH
AAGEAFIARAGGDEFAVLLRSPSPGAAAATCEAILEAFSTPFKVGAYSITIGTSIGYFET
HCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEC
DTSCDGAEESIRKADVAMYAAKDAGRHCARVYHPSLDESHERRQRLEQDLKRAVEDEEIY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEE
VRYQPIVDAQSGEVVAVEALARWSHPVHGDVPPDVFIPIAEISGLINAIGRQVLLHACRE
EEEECCEECCCCCEEEHHHHHHCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
MRETGLDLAVNLSPAQFWDGNLYDEVQQVLERTGFPPERLELEITESLLLRRPQVAAAVI
HHHCCCCEEEECCCHHCCCCCHHHHHHHHHHHCCCCHHHEEHHHHHHHHHCCCHHHHHHH
DRLRSLGIRMALDDFGTGFASIAYLQQLTIDRLKIDRSFLAPLESQPDMREVLISIVGLA
HHHHHCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHH
KAYHLEVCAEGIETPGQAQLARIAGCGRLQGWLFGRPQAASAFQPVALRA
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]