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The map label for this gene is yciR [C]

Identifier: 148550650

GI number: 148550650

Start: 101909

End: 104350

Strand: Direct

Name: yciR [C]

Synonym: Swit_5213

Alternate gene names: 148550650

Gene position: 101909-104350 (Clockwise)

Preceding gene: 148550649

Following gene: 148550651

Centisome position: 32.85

GC content: 63.02

Gene sequence:

>2442_bases
ATGTTCCCCTTTCTCTTTTGCCTGCGCGATCAACATGACGCGCCCTTGGTCATCCTCGCGGCTATAGTCTGTCTCCTGAC
GGCGGCAGCAACCGTTCGCCTGTGTCGCCAGGCGGCCTGGACAGACACGGGTTCGCGCAGCTTGTGGCTGACGATGGCGG
GGTTGACTGCCGGTCTTGGGATCTGGGCCACGCACTTCATCGCGATGCTGGGCTACGATCCCGGCATCGTCATGGGCTAT
CATGTCCAACAGACCGTGGTCTCGCTCTTGGTCGTGCTGGCAGGCGCGACAGCGGGCCTCTTCATTGCGACACGCGCGCC
GCACTGGCTCGGCTCGCTTCTTGCCGCTTCGGTTATGGGCGGCGGCGTCACGGCCATGCACTACCTTGGCATGGCGGCGC
TCGAAATGCCTGCGCTCATTCGCTGGAAGGCCGATTATGTCGCGGCCTCGGCCGTGTTCGCAATCGTCCCGCTAGTCTTG
GCGCTGCCCCTTGCGCTGCGCGGCAGATCGCTCGCCAAAGGCGCAGCGGCCGCTGGTCTGATCACCGCCGCCGTCGTCCT
GCTTCACTTTACCGGCATGACCGCGATCACGCTGATCCCGTCGCGTGGCGAATTCTCCCCCCTCAGCATGATGTCTCCCC
GCGCCATGTCGCTCTGGATATTTCTCGCGGCCTCCTGCACGATCGCTCTGACCGCGGCGGCGGCGATCACGAGCCGGCGG
ACGGGCATCAAATTGCGCCGACAGGAACGCGAGAATCAGCTTCGCGTCCAAGGCATGAAGGCCCAACTCGACCTAGCCCT
TGAGAATATGCACCAGGGCCTGTGCCTATACGACGGCGACGGTCGGCTTTTGCTCTGGAACCAGCGTTTCCTGGATCTAT
ACGGGCTTGGAAGCGATGCGCTCCAATGCGGAATGACGGTGGGACAAGTGATCCGCACCGGCATTGCCAACCATCTTCCC
GTTACCGAGGTCGAGCAGCGCGCAGCAGAAATCGAGCGTAACCTCAACCAGGCCCTGAGCGCTTCAGGAGACGCACCCGC
AATCTCGGAATATCCCGGCGTGGTGGTGAGCGTACGTTCGCGCGCGCTTCCCGACGGCGGATGGGTGAGCACCTTTGACG
ATATTACCCAGCAGCGCCGTTCGGAAGAACGAATCCGGCACCTGGCGCTGCATGATGGCCTGACCGGCCTGCCCAACCGG
CGTAGGTTCAACGATGTCGTCGACCGCGATCTGGACGTTACGGCGCGAGCCGGTTCGCGCCTGGGACTGGTCGTTGTCGA
CCTCGACAATTTCAAGGACATCAACGACAGCCGCGGCCATTCAGCCGGAGACCAAGCATTGAAGATGGTCGCCGCAGCGC
TCAAGGACGCGGTTCGCGAGAATGAACATGTCGCCCGGCTGGGTGGCGACGAATTCGCCGCCGCAATTCTGTACCGGGAA
GATTATGAGCTTGCCGACTTTGTGACGCGCCTGAGCACCGGGCTGGCGGCGATCAATGCCGGCAATGCGCACGATCTGAG
CGTCCATGCGAGCCTTGGCATCGCAACCTATCCGGCTGACAGCCAGGATCGCGAACAGCTGTGCAATCATGCCGATCTGG
CCATGTACCGGGCAAAAGGGACGGTAGGCGAGCGGATCTGCTATTACGAAAAAGGCATGGACGAGCAGGCGCGCGAACGC
CGGCAACTCGCGGCCGATCTTCGGGGCGCCGCCGCGCGCGGTGAGATGACGATCCTCTACCAGCCGCAGCGTTCGCTCAA
GGACGACAGGGTAAACGGCTATGAAGCTCTGCTGCGCTGGACCCACCCAAAGCGCGGCCTGGTCCCCCCTGACATCTTCA
TTCCCGTTGCTGAAGAAACCGGCGAGATCTTGGCGCTTGGCGAGTGGGTGCTGCGGCAAGCCTGTGAGGAGGCGGCCCGC
TGGGGTGACGGACTGACCGTGGCCATCAACCTCTCCGCCGTGCAGTTGAGCCAGGCGAGCCTGCCCGAGAGCGTGGCCCA
GACCCTTCTGGAGACCGGACTCGCACCAAGGCGTCTCGAACTGGAGATCACTGAAACCGCGATCATCGCCGACAAGCCGC
GCGCCTTGCATATTTTGCGTAGACTCAAGGCGATGGGGATCGCCATTGCCATCGACGATTTCGGCACCGGCTATTCCTCG
CTCGATACGCTCAACTCGTTCCCCTTCGACAAGATCAAGATCGACAAATCATTCGTCATCGGGTCCGAAGAGCGGCCGCA
GGCCAGAGCAATCATCAGGGCGGTGCTCGCGCTGGGCCACAGCCTTGGCGTCCCTGTGCTCGCCGAAGGGGTTGAGACCA
GTGGGCACGTCGATCTGCTGGTGGCTGAGGGATGCGACCAGGTCCAAGGCTATCTCTTCGGACGCCCCGGCCATGCACCA
AGCCTTCTTGCGAGGGAGCAGGCCCGACTGGCCGCCGGTTGA

Upstream 100 bases:

>100_bases
CGTATCGTTCGAATTTTACGCATTTTGTCGCAAAAGGCGGAACTCCGTTAATCACTTTCTGAAATGGGGACGGTTCAAAT
TCCTCCAGTTTCGATTGGCG

Downstream 100 bases:

>100_bases
TCCGCAGGTACGTCGCGCAACGACGCGGTAGCGTCGCGAGCGTCCTGAGAGCGCGATGTCGGAAGCGCGGGCGAACCGTC
CCCTTAGCTGCCAAGCTATC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 813; Mature: 813

Protein sequence:

>813_residues
MFPFLFCLRDQHDAPLVILAAIVCLLTAAATVRLCRQAAWTDTGSRSLWLTMAGLTAGLGIWATHFIAMLGYDPGIVMGY
HVQQTVVSLLVVLAGATAGLFIATRAPHWLGSLLAASVMGGGVTAMHYLGMAALEMPALIRWKADYVAASAVFAIVPLVL
ALPLALRGRSLAKGAAAAGLITAAVVLLHFTGMTAITLIPSRGEFSPLSMMSPRAMSLWIFLAASCTIALTAAAAITSRR
TGIKLRRQERENQLRVQGMKAQLDLALENMHQGLCLYDGDGRLLLWNQRFLDLYGLGSDALQCGMTVGQVIRTGIANHLP
VTEVEQRAAEIERNLNQALSASGDAPAISEYPGVVVSVRSRALPDGGWVSTFDDITQQRRSEERIRHLALHDGLTGLPNR
RRFNDVVDRDLDVTARAGSRLGLVVVDLDNFKDINDSRGHSAGDQALKMVAAALKDAVRENEHVARLGGDEFAAAILYRE
DYELADFVTRLSTGLAAINAGNAHDLSVHASLGIATYPADSQDREQLCNHADLAMYRAKGTVGERICYYEKGMDEQARER
RQLAADLRGAAARGEMTILYQPQRSLKDDRVNGYEALLRWTHPKRGLVPPDIFIPVAEETGEILALGEWVLRQACEEAAR
WGDGLTVAINLSAVQLSQASLPESVAQTLLETGLAPRRLELEITETAIIADKPRALHILRRLKAMGIAIAIDDFGTGYSS
LDTLNSFPFDKIKIDKSFVIGSEERPQARAIIRAVLALGHSLGVPVLAEGVETSGHVDLLVAEGCDQVQGYLFGRPGHAP
SLLAREQARLAAG

Sequences:

>Translated_813_residues
MFPFLFCLRDQHDAPLVILAAIVCLLTAAATVRLCRQAAWTDTGSRSLWLTMAGLTAGLGIWATHFIAMLGYDPGIVMGY
HVQQTVVSLLVVLAGATAGLFIATRAPHWLGSLLAASVMGGGVTAMHYLGMAALEMPALIRWKADYVAASAVFAIVPLVL
ALPLALRGRSLAKGAAAAGLITAAVVLLHFTGMTAITLIPSRGEFSPLSMMSPRAMSLWIFLAASCTIALTAAAAITSRR
TGIKLRRQERENQLRVQGMKAQLDLALENMHQGLCLYDGDGRLLLWNQRFLDLYGLGSDALQCGMTVGQVIRTGIANHLP
VTEVEQRAAEIERNLNQALSASGDAPAISEYPGVVVSVRSRALPDGGWVSTFDDITQQRRSEERIRHLALHDGLTGLPNR
RRFNDVVDRDLDVTARAGSRLGLVVVDLDNFKDINDSRGHSAGDQALKMVAAALKDAVRENEHVARLGGDEFAAAILYRE
DYELADFVTRLSTGLAAINAGNAHDLSVHASLGIATYPADSQDREQLCNHADLAMYRAKGTVGERICYYEKGMDEQARER
RQLAADLRGAAARGEMTILYQPQRSLKDDRVNGYEALLRWTHPKRGLVPPDIFIPVAEETGEILALGEWVLRQACEEAAR
WGDGLTVAINLSAVQLSQASLPESVAQTLLETGLAPRRLELEITETAIIADKPRALHILRRLKAMGIAIAIDDFGTGYSS
LDTLNSFPFDKIKIDKSFVIGSEERPQARAIIRAVLALGHSLGVPVLAEGVETSGHVDLLVAEGCDQVQGYLFGRPGHAP
SLLAREQARLAAG
>Mature_813_residues
MFPFLFCLRDQHDAPLVILAAIVCLLTAAATVRLCRQAAWTDTGSRSLWLTMAGLTAGLGIWATHFIAMLGYDPGIVMGY
HVQQTVVSLLVVLAGATAGLFIATRAPHWLGSLLAASVMGGGVTAMHYLGMAALEMPALIRWKADYVAASAVFAIVPLVL
ALPLALRGRSLAKGAAAAGLITAAVVLLHFTGMTAITLIPSRGEFSPLSMMSPRAMSLWIFLAASCTIALTAAAAITSRR
TGIKLRRQERENQLRVQGMKAQLDLALENMHQGLCLYDGDGRLLLWNQRFLDLYGLGSDALQCGMTVGQVIRTGIANHLP
VTEVEQRAAEIERNLNQALSASGDAPAISEYPGVVVSVRSRALPDGGWVSTFDDITQQRRSEERIRHLALHDGLTGLPNR
RRFNDVVDRDLDVTARAGSRLGLVVVDLDNFKDINDSRGHSAGDQALKMVAAALKDAVRENEHVARLGGDEFAAAILYRE
DYELADFVTRLSTGLAAINAGNAHDLSVHASLGIATYPADSQDREQLCNHADLAMYRAKGTVGERICYYEKGMDEQARER
RQLAADLRGAAARGEMTILYQPQRSLKDDRVNGYEALLRWTHPKRGLVPPDIFIPVAEETGEILALGEWVLRQACEEAAR
WGDGLTVAINLSAVQLSQASLPESVAQTLLETGLAPRRLELEITETAIIADKPRALHILRRLKAMGIAIAIDDFGTGYSS
LDTLNSFPFDKIKIDKSFVIGSEERPQARAIIRAVLALGHSLGVPVLAEGVETSGHVDLLVAEGCDQVQGYLFGRPGHAP
SLLAREQARLAAG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=426, Percent_Identity=36.150234741784, Blast_Score=281, Evalue=2e-76,
Organism=Escherichia coli, GI87081921, Length=424, Percent_Identity=31.6037735849057, Blast_Score=227, Evalue=3e-60,
Organism=Escherichia coli, GI226510982, Length=426, Percent_Identity=29.3427230046948, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1787055, Length=250, Percent_Identity=33.2, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1786507, Length=231, Percent_Identity=33.7662337662338, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1790496, Length=235, Percent_Identity=33.6170212765957, Blast_Score=130, Evalue=5e-31,
Organism=Escherichia coli, GI1788502, Length=263, Percent_Identity=34.6007604562738, Blast_Score=129, Evalue=9e-31,
Organism=Escherichia coli, GI87081845, Length=237, Percent_Identity=35.4430379746835, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI87081743, Length=232, Percent_Identity=31.8965517241379, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87081980, Length=241, Percent_Identity=31.9502074688797, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87082096, Length=442, Percent_Identity=25.7918552036199, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788849, Length=431, Percent_Identity=25.9860788863109, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788381, Length=435, Percent_Identity=25.7471264367816, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=32.183908045977, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=35, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=32.7586206896552, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI87081977, Length=153, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787410, Length=161, Percent_Identity=32.2981366459627, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081974, Length=83, Percent_Identity=37.3493975903614, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=35.1515151515151, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=29.0123456790123, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789650, Length=420, Percent_Identity=20, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=32.9411764705882, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 87777; Mature: 87777

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50924 MHYT ; PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPFLFCLRDQHDAPLVILAAIVCLLTAAATVRLCRQAAWTDTGSRSLWLTMAGLTAGLG
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHH
IWATHFIAMLGYDPGIVMGYHVQQTVVSLLVVLAGATAGLFIATRAPHWLGSLLAASVMG
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHC
GGVTAMHYLGMAALEMPALIRWKADYVAASAVFAIVPLVLALPLALRGRSLAKGAAAAGL
CCHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ITAAVVLLHFTGMTAITLIPSRGEFSPLSMMSPRAMSLWIFLAASCTIALTAAAAITSRR
HHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGIKLRRQERENQLRVQGMKAQLDLALENMHQGLCLYDGDGRLLLWNQRFLDLYGLGSDA
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEECCCCCEEEEECHHHHHHCCCHHH
LQCGMTVGQVIRTGIANHLPVTEVEQRAAEIERNLNQALSASGDAPAISEYPGVVVSVRS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEHH
RALPDGGWVSTFDDITQQRRSEERIRHLALHDGLTGLPNRRRFNDVVDRDLDVTARAGSR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEECCCCC
LGLVVVDLDNFKDINDSRGHSAGDQALKMVAAALKDAVRENEHVARLGGDEFAAAILYRE
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHEEEHEEC
DYELADFVTRLSTGLAAINAGNAHDLSVHASLGIATYPADSQDREQLCNHADLAMYRAKG
CCHHHHHHHHHHHCHHEEECCCCCEEEEEEECCEEECCCCCHHHHHHHCCHHHHHEECCC
TVGERICYYEKGMDEQARERRQLAADLRGAAARGEMTILYQPQRSLKDDRVNGYEALLRW
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHC
THPKRGLVPPDIFIPVAEETGEILALGEWVLRQACEEAARWGDGLTVAINLSAVQLSQAS
CCCCCCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEHHHC
LPESVAQTLLETGLAPRRLELEITETAIIADKPRALHILRRLKAMGIAIAIDDFGTGYSS
CHHHHHHHHHHCCCCCCEEEEEEECEEEECCCCHHHHHHHHHHHCCEEEEEECCCCCHHH
LDTLNSFPFDKIKIDKSFVIGSEERPQARAIIRAVLALGHSLGVPVLAEGVETSGHVDLL
HHHHHCCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEE
VAEGCDQVQGYLFGRPGHAPSLLAREQARLAAG
EECCCCHHCCEEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFPFLFCLRDQHDAPLVILAAIVCLLTAAATVRLCRQAAWTDTGSRSLWLTMAGLTAGLG
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHH
IWATHFIAMLGYDPGIVMGYHVQQTVVSLLVVLAGATAGLFIATRAPHWLGSLLAASVMG
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHC
GGVTAMHYLGMAALEMPALIRWKADYVAASAVFAIVPLVLALPLALRGRSLAKGAAAAGL
CCHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ITAAVVLLHFTGMTAITLIPSRGEFSPLSMMSPRAMSLWIFLAASCTIALTAAAAITSRR
HHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGIKLRRQERENQLRVQGMKAQLDLALENMHQGLCLYDGDGRLLLWNQRFLDLYGLGSDA
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEECCCCCEEEEECHHHHHHCCCHHH
LQCGMTVGQVIRTGIANHLPVTEVEQRAAEIERNLNQALSASGDAPAISEYPGVVVSVRS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEHH
RALPDGGWVSTFDDITQQRRSEERIRHLALHDGLTGLPNRRRFNDVVDRDLDVTARAGSR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEECCCCC
LGLVVVDLDNFKDINDSRGHSAGDQALKMVAAALKDAVRENEHVARLGGDEFAAAILYRE
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHEEEHEEC
DYELADFVTRLSTGLAAINAGNAHDLSVHASLGIATYPADSQDREQLCNHADLAMYRAKG
CCHHHHHHHHHHHCHHEEECCCCCEEEEEEECCEEECCCCCHHHHHHHCCHHHHHEECCC
TVGERICYYEKGMDEQARERRQLAADLRGAAARGEMTILYQPQRSLKDDRVNGYEALLRW
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHC
THPKRGLVPPDIFIPVAEETGEILALGEWVLRQACEEAARWGDGLTVAINLSAVQLSQAS
CCCCCCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEHHHC
LPESVAQTLLETGLAPRRLELEITETAIIADKPRALHILRRLKAMGIAIAIDDFGTGYSS
CHHHHHHHHHHCCCCCCEEEEEEECEEEECCCCHHHHHHHHHHHCCEEEEEECCCCCHHH
LDTLNSFPFDKIKIDKSFVIGSEERPQARAIIRAVLALGHSLGVPVLAEGVETSGHVDLL
HHHHHCCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEE
VAEGCDQVQGYLFGRPGHAPSLLAREQARLAAG
EECCCCHHCCEEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]