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The map label for this gene is galE [H]

Identifier: 148380737

GI number: 148380737

Start: 2938099

End: 2939079

Strand: Reverse

Name: galE [H]

Synonym: CBO2777

Alternate gene names: 148380737

Gene position: 2939079-2938099 (Counterclockwise)

Preceding gene: 148380738

Following gene: 148380736

Centisome position: 75.61

GC content: 31.6

Gene sequence:

>981_bases
TTGGCTATATTAGTATGTGGAGGAGCAGGATATATAGGAAGTCATGCGGTGGCAGCCTTAATTGAGAAAAATGAAGAAGT
AGTTATTGTAGATAATTTAGTTACAGGTCATGAACAAGCCATATGCGGTGGTAAATTTTATAAAGGCGATTTAAGAGATA
AAGAATTTTTAAATAAGGTTTTTAACCAAAATAAAATAGATGCAGTTATTCATTTTGCAGCTTTTTCTTTGGTTGGAGAA
AGTATGGAAGAACCTTTTAAATATTATAATAATAATGTATGTGGAACGTTAAGCTTATTAGAAACAATGAAAGAATATAA
TGTACAGAAAATAGTATTTTCATCTACAGCAGCAACTTATGGAGAACCAGAAAATATACCAATATTAGAAGAAGATCTTA
CAGAGCCTACTAATGCTTATGGAGAAACTAAACTTGCAGTAGAAAAAATGCTTAAATGGGCAGAAATGGCTTATAATATA
AAATATGTTGTATTAAGATATTTTAATGTAGCAGGAGCTCACGAAAGCGGTAATATAGGAGAGGCACATAAGGTAGAAAG
TCATCTGATACCTATAATACTTCAAGTAGCATTAGGACGAAGAGAAAAAATAATGATATATGGAGATGATTATAATACTA
AAGATGGAAGTTGTGTAAGAGATTATATTCATGTAATGGATTTAGTAGAAGCTCATATTCTAGCACTAGAAAAATTAAGA
AGAGATAATACTAGTGCTACATATAATTTAGGTAATGGAGAGGGCTTTAGTGTTAAAGAAGTTATAGATATATGCAGGAA
AGTTACAGGGCATGCTATACCATCAGAAATAGCTGCAAGAAGATCAGGAGATCCAGCTATACTTATAGCATCATCTGAAA
AAATAATAAAAGAACTAGGTTGGAATCCTAAGAAAGCTTCTTTAGAAAGTATAATTGATAGTGCTTGGAAATGGCACAGA
TCCCATCCAGATGGATATTAG

Upstream 100 bases:

>100_bases
TAACTAATAAGTTACTTTTATTTAATAGAGTAATATTAAAATAATGTGTATAATTAATAATATGTACTTTATTGTTAAAT
TCAGATAGGAGTGATATTAG

Downstream 100 bases:

>100_bases
AATATTAAAGGAATACAAGGGAGTGTAGCTTGAAATTATGGAAGATAAATTTATAGATTTAAATTTAAAGTTTAATGAGG
AAATAGATAAAAAATCCATA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKVFNQNKIDAVIHFAAFSLVGE
SMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATYGEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNI
KYVVLRYFNVAGAHESGNIGEAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
RDNTSATYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELGWNPKKASLESIIDSAWKWHR
SHPDGY

Sequences:

>Translated_326_residues
MAILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKVFNQNKIDAVIHFAAFSLVGE
SMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATYGEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNI
KYVVLRYFNVAGAHESGNIGEAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
RDNTSATYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELGWNPKKASLESIIDSAWKWHR
SHPDGY
>Mature_325_residues
AILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKVFNQNKIDAVIHFAAFSLVGES
MEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATYGEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNIK
YVVLRYFNVAGAHESGNIGEAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLRR
DNTSATYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELGWNPKKASLESIIDSAWKWHRS
HPDGY

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=346, Percent_Identity=40.1734104046243, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI56118217, Length=346, Percent_Identity=40.1734104046243, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI189083684, Length=346, Percent_Identity=40.1734104046243, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI7657641, Length=337, Percent_Identity=28.1899109792285, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI42516563, Length=326, Percent_Identity=27.6073619631902, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI193211614, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI8393516, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI116268111, Length=289, Percent_Identity=26.2975778546713, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=40.9495548961424, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1788353, Length=359, Percent_Identity=27.5766016713092, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=26.0744985673352, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=29.9625468164794, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788366, Length=347, Percent_Identity=23.0547550432277, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=40.2298850574713, Blast_Score=247, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=40, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17539532, Length=312, Percent_Identity=27.8846153846154, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17568069, Length=346, Percent_Identity=28.9017341040462, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=355, Percent_Identity=24.7887323943662, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=43.731778425656, Blast_Score=269, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6321437, Length=341, Percent_Identity=25.5131964809384, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19923002, Length=350, Percent_Identity=42, Blast_Score=257, Evalue=7e-69,
Organism=Drosophila melanogaster, GI21356223, Length=329, Percent_Identity=28.2674772036474, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36272; Mature: 36141

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKV
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHEECCCCCCCCCCCHHHHHHH
FNQNKIDAVIHFAAFSLVGESMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATY
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEEEECCCCCC
GEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNIKYVVLRYFNVAGAHESGNIG
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDNTSATYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELG
CCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCHHHHHHCC
WNPKKASLESIIDSAWKWHRSHPDGY
CCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AILVCGGAGYIGSHAVAALIEKNEEVVIVDNLVTGHEQAICGGKFYKGDLRDKEFLNKV
EEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHEECCCCCCCCCCCHHHHHHH
FNQNKIDAVIHFAAFSLVGESMEEPFKYYNNNVCGTLSLLETMKEYNVQKIVFSSTAATY
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEEEECCCCCC
GEPENIPILEEDLTEPTNAYGETKLAVEKMLKWAEMAYNIKYVVLRYFNVAGAHESGNIG
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EAHKVESHLIPIILQVALGRREKIMIYGDDYNTKDGSCVRDYIHVMDLVEAHILALEKLR
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDNTSATYNLGNGEGFSVKEVIDICRKVTGHAIPSEIAARRSGDPAILIASSEKIIKELG
CCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCHHHHHHCC
WNPKKASLESIIDSAWKWHRSHPDGY
CCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]