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The map label for this gene is rfbB [C]

Identifier: 148380682

GI number: 148380682

Start: 2874615

End: 2875679

Strand: Reverse

Name: rfbB [C]

Synonym: CBO2724

Alternate gene names: 148380682

Gene position: 2875679-2874615 (Counterclockwise)

Preceding gene: 148380683

Following gene: 148380681

Centisome position: 73.98

GC content: 29.3

Gene sequence:

>1065_bases
ATGAATATACTAGTAACTGGTGGCGCAGGATTTATAGGAAGATGGGTAGTTAAAACACTACTTTTAGAAGGACATGAAGT
TGTAGCATTAGATAACCTATCTAATGGAAGGTTGGAAAATATATATGAATTCGTATATGAAGATAAATTAGATTACATAA
AGAACAATAAAGAAAATATAAGTGGTTTAGAAGGAGAAAATTTTAAGTTTATAAAAGGTGACATAAGAGATGAAGCTTTA
TTAGATGAATTATTTAAAAAAAATAAATTTCATATAGTATATCATTTAGGAGCATCCATAAATGTACAAGAAAGTATAGA
TGATCCTAAAACTACTTTTTATAATGATACAATAGGAACCTTTAATATACTAGAAAAATGTAAAACTCAAATGTTTGGTA
AAAAGGCAAAAATGGAAGGCGATAAATGGATTCTAGACAAAAATGAAAAAGCTTATCCTTGTAAAGTAGTTTTTATGAGT
ACTTGTATGGTATATGATAAAGCACCTGAAGTGGGAATAGATGAGGAGCATAGGGTAAAACCAATATCCCCTTATGGTGG
AGCTAAGATAGCAGCAGAAAATATGGTATTATCCTATTACAATGCTTATAAATTGCCTACAGTAGTTATAAGACCATTTA
ATACTTATGGACCTTTTCAAAAAACCAATGGAGAAGGTGGAGTAGTTGCTATATTTATAAATAATTATCTACAAAATAAA
AACTTAAACATATATGGCACAGGAGATCAAACAAGAGATTTGTTATATGTAAAAGATTGTGCAAATTTTGTAGTAGAAGC
GGGATATAAGGATTCTGTAAATGGTCAAATAGTAAATGCAGGAACAGGAAGAGATATTACCATAAATGAACTTGCACAAA
TTATATCCAGTGGAAAAGTAAAAATAAATCATGTACCTCATATTCATCCACAAAGCGAAATAATGAAGCTAAAATGTAAT
TACAAAAAGGCAAAAGAGTTAATGGGGTGGGAGCCTAATTACACTTTAGAAGGAGGTATAGAAGAAACTAAACAGTGGAT
TAAAAACCATAAAAATCTAATATAA

Upstream 100 bases:

>100_bases
TTCAATTTATAAATAGTAACAAGCATTAATAAAAGAATTAGATTTTTATAATTTAGTATAGTGCTTATACTAAAAAGTTT
TTGTAAAAGGAAGTGGGAAT

Downstream 100 bases:

>100_bases
GCATAAAAATTAATAATATTTTAGTTTTAAAATATAATTATATTAATTGGAATTTTCAAAAGTAAAAATTTTTATATTTT
TTATAGTTTGAAATTATAAT

Product: dTDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNILVTGGAGFIGRWVVKTLLLEGHEVVALDNLSNGRLENIYEFVYEDKLDYIKNNKENISGLEGENFKFIKGDIRDEAL
LDELFKKNKFHIVYHLGASINVQESIDDPKTTFYNDTIGTFNILEKCKTQMFGKKAKMEGDKWILDKNEKAYPCKVVFMS
TCMVYDKAPEVGIDEEHRVKPISPYGGAKIAAENMVLSYYNAYKLPTVVIRPFNTYGPFQKTNGEGGVVAIFINNYLQNK
NLNIYGTGDQTRDLLYVKDCANFVVEAGYKDSVNGQIVNAGTGRDITINELAQIISSGKVKINHVPHIHPQSEIMKLKCN
YKKAKELMGWEPNYTLEGGIEETKQWIKNHKNLI

Sequences:

>Translated_354_residues
MNILVTGGAGFIGRWVVKTLLLEGHEVVALDNLSNGRLENIYEFVYEDKLDYIKNNKENISGLEGENFKFIKGDIRDEAL
LDELFKKNKFHIVYHLGASINVQESIDDPKTTFYNDTIGTFNILEKCKTQMFGKKAKMEGDKWILDKNEKAYPCKVVFMS
TCMVYDKAPEVGIDEEHRVKPISPYGGAKIAAENMVLSYYNAYKLPTVVIRPFNTYGPFQKTNGEGGVVAIFINNYLQNK
NLNIYGTGDQTRDLLYVKDCANFVVEAGYKDSVNGQIVNAGTGRDITINELAQIISSGKVKINHVPHIHPQSEIMKLKCN
YKKAKELMGWEPNYTLEGGIEETKQWIKNHKNLI
>Mature_354_residues
MNILVTGGAGFIGRWVVKTLLLEGHEVVALDNLSNGRLENIYEFVYEDKLDYIKNNKENISGLEGENFKFIKGDIRDEAL
LDELFKKNKFHIVYHLGASINVQESIDDPKTTFYNDTIGTFNILEKCKTQMFGKKAKMEGDKWILDKNEKAYPCKVVFMS
TCMVYDKAPEVGIDEEHRVKPISPYGGAKIAAENMVLSYYNAYKLPTVVIRPFNTYGPFQKTNGEGGVVAIFINNYLQNK
NLNIYGTGDQTRDLLYVKDCANFVVEAGYKDSVNGQIVNAGTGRDITINELAQIISSGKVKINHVPHIHPQSEIMKLKCN
YKKAKELMGWEPNYTLEGGIEETKQWIKNHKNLI

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=357, Percent_Identity=31.3725490196078, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI7657641, Length=360, Percent_Identity=31.1111111111111, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI56237023, Length=372, Percent_Identity=26.6129032258064, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI56118217, Length=372, Percent_Identity=26.6129032258064, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI189083684, Length=372, Percent_Identity=26.6129032258064, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4504031, Length=372, Percent_Identity=24.7311827956989, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788353, Length=364, Percent_Identity=27.7472527472527, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI48994969, Length=360, Percent_Identity=28.6111111111111, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786974, Length=378, Percent_Identity=25.6613756613757, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788366, Length=370, Percent_Identity=24.3243243243243, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17539532, Length=358, Percent_Identity=26.8156424581006, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17568069, Length=356, Percent_Identity=25.8426966292135, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=372, Percent_Identity=26.3440860215054, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71982038, Length=370, Percent_Identity=25.6756756756757, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115532424, Length=369, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319493, Length=373, Percent_Identity=24.1286863270777, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356223, Length=359, Percent_Identity=30.3621169916435, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI19923002, Length=372, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 40100; Mature: 40100

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVTGGAGFIGRWVVKTLLLEGHEVVALDNLSNGRLENIYEFVYEDKLDYIKNNKENI
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SGLEGENFKFIKGDIRDEALLDELFKKNKFHIVYHLGASINVQESIDDPKTTFYNDTIGT
CCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCEEEHHCCCCCCCEEECCCCCH
FNILEKCKTQMFGKKAKMEGDKWILDKNEKAYPCKVVFMSTCMVYDKAPEVGIDEEHRVK
HHHHHHHHHHHHCCHHCCCCCEEEECCCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCCEE
PISPYGGAKIAAENMVLSYYNAYKLPTVVIRPFNTYGPFQKTNGEGGVVAIFINNYLQNK
CCCCCCCCEEEHHHEEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECHHCCC
NLNIYGTGDQTRDLLYVKDCANFVVEAGYKDSVNGQIVNAGTGRDITINELAQIISSGKV
CEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCEEEECCCCCEEEHHHHHHHHHCCCE
KINHVPHIHPQSEIMKLKCNYKKAKELMGWEPNYTLEGGIEETKQWIKNHKNLI
EEECCCCCCCHHHEEEEECCHHHHHHHCCCCCCCEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNILVTGGAGFIGRWVVKTLLLEGHEVVALDNLSNGRLENIYEFVYEDKLDYIKNNKENI
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SGLEGENFKFIKGDIRDEALLDELFKKNKFHIVYHLGASINVQESIDDPKTTFYNDTIGT
CCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCEEEHHCCCCCCCEEECCCCCH
FNILEKCKTQMFGKKAKMEGDKWILDKNEKAYPCKVVFMSTCMVYDKAPEVGIDEEHRVK
HHHHHHHHHHHHCCHHCCCCCEEEECCCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCCEE
PISPYGGAKIAAENMVLSYYNAYKLPTVVIRPFNTYGPFQKTNGEGGVVAIFINNYLQNK
CCCCCCCCEEEHHHEEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECHHCCC
NLNIYGTGDQTRDLLYVKDCANFVVEAGYKDSVNGQIVNAGTGRDITINELAQIISSGKV
CEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCEEEECCCCCEEEHHHHHHHHHCCCE
KINHVPHIHPQSEIMKLKCNYKKAKELMGWEPNYTLEGGIEETKQWIKNHKNLI
EEECCCCCCCHHHEEEEECCHHHHHHHCCCCCCCEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]