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The map label for this gene is mraY [H]

Identifier: 148379431

GI number: 148379431

Start: 1593198

End: 1594151

Strand: Direct

Name: mraY [H]

Synonym: CBO1459

Alternate gene names: 148379431

Gene position: 1593198-1594151 (Clockwise)

Preceding gene: 148379430

Following gene: 148379432

Centisome position: 40.99

GC content: 30.71

Gene sequence:

>954_bases
ATGAATAGAATAGTATATGCAGTGCTTTTAGCCTTTTTAATATCAATATTAGGAGGACCAATATTAATACCTTTATTACA
CAAATTTAAATTTGGACAAAATATAAGAGAAGAGGGACCAGAAAGTCATAGAAAAAAAGCAGGTACCCCTACTATGGGAG
GAGTAATATTTATATTATCATCTATAATAACAATGGCTTTAACTATAAGAAGGCCAGGGGATGAAGCTATGGTAGCTTTA
TATGCTTTTATAGCTTTTGGAATAATAGGAGCTTTAGATGATGGATTAAAAATAATTCATAAAAATAACTTAGGATTAAG
AGCTTACCAAAAAATGCTATTAATCTTAGTGGTATCTGGTATATTTGGATATTATTCTGCCAATAATCCTAATATAGGTA
CTTCAATAATAATGCCTTTTACTAGGAAAAGTTTAGATTTAGGAGCGTTTTATATACCAGGTATAATAATATATTTTGCA
GCTACAACTAATGCTGTTAATTTAACAGATGGATTAGATGGATTAGCTACTTCTGTTACATTACTTGTTATGACTTTCTT
TGCTTTAGTGAGTTTCGGAATGGGTCACTATACTTTAGCCATATTTTGTGCAGTGGTAGCAGGAGCTCTTTTAGGATTTT
TAAGATATAATGCATTCCCAGCCCAAGTATTTATGGGAGATACAGGTTCTTTAGCTTTAGGTGGAGCAGTAGCTGCAGTG
GCTATGATACTAAAATTGGAAATATTAGTTATAATAGTAGGTGGAATATATGTATTAGAAACGTTATCTGTAATAATACA
GGTTCTATCCTTTAAGCTTACAGGAAAAAGAGTATTTAAAATGAGCCCTATACATCATCACTTTGAACTAAGTGGATGGC
ATGAAACTAAAGTAGTATCTGTTTTTTCAATAATTACAGTAATATTATGTTTAGTTGCTTTCTTAGCATTATAA

Upstream 100 bases:

>100_bases
AAGCATCTAGAGCTATGAAGCTAGAAGAAATAGTAAAAGAACTAAGGATAAAACAAGAAAAATAGGAGGTGACTTGCTCA
CATAATTAGAGCAATTATTT

Downstream 100 bases:

>100_bases
TAAGCATTAGATAATGTAATTATAGATATGAATTTATTTTGAACCTATAAGTAATATAATAGGAGGAATTAGCAGGATAT
GAAAAAAACTAAAACTAAAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNRIVYAVLLAFLISILGGPILIPLLHKFKFGQNIREEGPESHRKKAGTPTMGGVIFILSSIITMALTIRRPGDEAMVAL
YAFIAFGIIGALDDGLKIIHKNNLGLRAYQKMLLILVVSGIFGYYSANNPNIGTSIIMPFTRKSLDLGAFYIPGIIIYFA
ATTNAVNLTDGLDGLATSVTLLVMTFFALVSFGMGHYTLAIFCAVVAGALLGFLRYNAFPAQVFMGDTGSLALGGAVAAV
AMILKLEILVIIVGGIYVLETLSVIIQVLSFKLTGKRVFKMSPIHHHFELSGWHETKVVSVFSIITVILCLVAFLAL

Sequences:

>Translated_317_residues
MNRIVYAVLLAFLISILGGPILIPLLHKFKFGQNIREEGPESHRKKAGTPTMGGVIFILSSIITMALTIRRPGDEAMVAL
YAFIAFGIIGALDDGLKIIHKNNLGLRAYQKMLLILVVSGIFGYYSANNPNIGTSIIMPFTRKSLDLGAFYIPGIIIYFA
ATTNAVNLTDGLDGLATSVTLLVMTFFALVSFGMGHYTLAIFCAVVAGALLGFLRYNAFPAQVFMGDTGSLALGGAVAAV
AMILKLEILVIIVGGIYVLETLSVIIQVLSFKLTGKRVFKMSPIHHHFELSGWHETKVVSVFSIITVILCLVAFLAL
>Mature_317_residues
MNRIVYAVLLAFLISILGGPILIPLLHKFKFGQNIREEGPESHRKKAGTPTMGGVIFILSSIITMALTIRRPGDEAMVAL
YAFIAFGIIGALDDGLKIIHKNNLGLRAYQKMLLILVVSGIFGYYSANNPNIGTSIIMPFTRKSLDLGAFYIPGIIIYFA
ATTNAVNLTDGLDGLATSVTLLVMTFFALVSFGMGHYTLAIFCAVVAGALLGFLRYNAFPAQVFMGDTGSLALGGAVAAV
AMILKLEILVIIVGGIYVLETLSVIIQVLSFKLTGKRVFKMSPIHHHFELSGWHETKVVSVFSIITVILCLVAFLAL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=335, Percent_Identity=42.9850746268657, Blast_Score=245, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 34188; Mature: 34188

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIVYAVLLAFLISILGGPILIPLLHKFKFGQNIREEGPESHRKKAGTPTMGGVIFILS
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCCHHHHHHHHH
SIITMALTIRRPGDEAMVALYAFIAFGIIGALDDGLKIIHKNNLGLRAYQKMLLILVVSG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHHH
IFGYYSANNPNIGTSIIMPFTRKSLDLGAFYIPGIIIYFAATTNAVNLTDGLDGLATSVT
HHHHCCCCCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LLVMTFFALVSFGMGHYTLAIFCAVVAGALLGFLRYNAFPAQVFMGDTGSLALGGAVAAV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
AMILKLEILVIIVGGIYVLETLSVIIQVLSFKLTGKRVFKMSPIHHHFELSGWHETKVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCHHHHHH
VFSIITVILCLVAFLAL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRIVYAVLLAFLISILGGPILIPLLHKFKFGQNIREEGPESHRKKAGTPTMGGVIFILS
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCCHHHHHHHHH
SIITMALTIRRPGDEAMVALYAFIAFGIIGALDDGLKIIHKNNLGLRAYQKMLLILVVSG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHHHHHH
IFGYYSANNPNIGTSIIMPFTRKSLDLGAFYIPGIIIYFAATTNAVNLTDGLDGLATSVT
HHHHCCCCCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LLVMTFFALVSFGMGHYTLAIFCAVVAGALLGFLRYNAFPAQVFMGDTGSLALGGAVAAV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
AMILKLEILVIIVGGIYVLETLSVIIQVLSFKLTGKRVFKMSPIHHHFELSGWHETKVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCHHHHHH
VFSIITVILCLVAFLAL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA