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The map label for this gene is murQ

Identifier: 148379322

GI number: 148379322

Start: 1467592

End: 1468500

Strand: Direct

Name: murQ

Synonym: CBO1343

Alternate gene names: 148379322

Gene position: 1467592-1468500 (Clockwise)

Preceding gene: 148379321

Following gene: 148379323

Centisome position: 37.76

GC content: 32.34

Gene sequence:

>909_bases
ATGACCAATATTAGTTTAGATAAATTAGTAACTGAGAGTAGAAATGAAAATACTAAAAATATAGATAGAGTTGAAACTTT
AGAGATGTTAAAGATGATAAATAATGAAGATAAAAAGGTTGCAGAAGCTGTAGAAAAAGAGCTTATTCATATAGCAAAGG
CTGTTGATAAAATAGGAGAAGCATTTTTAAATGGGGGTAGACTTATATATGTAGGAGCTGGTACATCAGGAAGATTAGGA
GTATTAGATGCATCAGAGTGTCCACCAACATATGGGGTGAGTTATGATTTGGTAAGAGGGATTATAGCAGGAGGAGAATC
GGCTATGTTTAAAGCTAGGGAAGGAGCAGAGGATTCTAAAAAACTTTGTATTAAAGATTTGAAAAATATTAATTTTGGTA
AAAATGATATATTGGCTGGAATTGCAGCTAGTGGAAGAACTCCTTATGTTATAGGAGGATTAGAATATGCAAATGGGATA
GGTGCTACAACAATTTCAGTTACGTGTAATCCAGAATCAGAAATGTCTAAGATTGCAAACATTTCAATAGCACCAGTAGT
AGGGCCAGAAGCTATAACAGGATCTACTAGAATGAAGGCAGGAACAGCTCAAAAAATGGTTCTAAACATGTTATCAACGG
GTGCTATGGTTAAAACAGGCAAGGTTTATGGTAACTTGATGGTTGATTTAAAAGCTACTAATGAGAAATTGGTAGAAAGA
GCTAAAAGAATTGTTATGCAGGCTACAGGATCTAAAAGAGAGCAGGTAGAAAAAATTCTTAAAGAAACAAATTTTGATGT
TAAGTTGTCCATTTTTATGATAGAGAGTTCATTAGATAAAATAAAAGCTAAGGAAATATTAGACAAAAATAAAGGATATA
TAGTAGAAGCAATAAAAGAAATAAGTTAA

Upstream 100 bases:

>100_bases
TAAACAATATACTTGAAATTTTATTTCATAAGAATATAATAAAGATAAAAGAAAAGGTTTTCAGATTCTTTGATATATAA
CTTATGAGGAGGATTTAGGT

Downstream 100 bases:

>100_bases
ACACAAAATAAATAGATAAAAATAGAATAATTATAGGGTGTAATTTAGAAATAAGATTATTGTTTAAATTTAAAACGCTC
AGTTATATTTAAAAATAAAG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGEAFLNGGRLIYVGAGTSGRLG
VLDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSKKLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGI
GATTISVTCNPESEMSKIANISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVER
AKRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKEIS

Sequences:

>Translated_302_residues
MTNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGEAFLNGGRLIYVGAGTSGRLG
VLDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSKKLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGI
GATTISVTCNPESEMSKIANISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVER
AKRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKEIS
>Mature_301_residues
TNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGEAFLNGGRLIYVGAGTSGRLGV
LDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSKKLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGIG
ATTISVTCNPESEMSKIANISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVERA
KRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKEIS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=295, Percent_Identity=55.9322033898305, Blast_Score=325, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_CLOB1 (A7FTM1)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001383698.1
- ProteinModelPortal:   A7FTM1
- SMR:   A7FTM1
- STRING:   A7FTM1
- GeneID:   5397556
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_1371
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   SMIGVGK
- ProtClustDB:   PRK05441
- BioCyc:   CBOT441770:CLB_1371-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 32610; Mature: 32479

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 86-86 ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGE
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AFLNGGRLIYVGAGTSGRLGVLDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSK
HHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHH
KLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGIGATTISVTCNPESEMSKIAN
HHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEECHHHCCCCCCEEEEEEECCHHHHHHHHC
ISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVER
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECEEEEEEEEEEECCHHHHHHH
AKRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKE
HHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHCCCCHHHHHHHH
IS
CC
>Mature Secondary Structure 
TNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGE
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AFLNGGRLIYVGAGTSGRLGVLDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSK
HHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHH
KLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGIGATTISVTCNPESEMSKIAN
HHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEECHHHCCCCCCEEEEEEECCHHHHHHHHC
ISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVER
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECEEEEEEEEEEECCHHHHHHH
AKRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKE
HHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHCCCCHHHHHHHH
IS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA