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The map label for this gene is trkA [H]

Identifier: 148379297

GI number: 148379297

Start: 1435741

End: 1437108

Strand: Direct

Name: trkA [H]

Synonym: CBO1318

Alternate gene names: 148379297

Gene position: 1435741-1437108 (Clockwise)

Preceding gene: 148379296

Following gene: 148379298

Centisome position: 36.94

GC content: 29.31

Gene sequence:

>1368_bases
ATGCATGTTATAATTGTAGGAAATGGGAAGGTAGGTTACACTTTAGCAAAGCACTTATCTCAAGAAAATAATGATGTGAT
TGTTATTGATAAAAATGCTGAAGCACTTCAGAAGGCTATGGATAATCTTGATGTAATGTGTATTAAAGGTAATGGTACAA
GAGTAAGTGTGCTTAAGGAGGCCGAAATTAGTAGAGCAGATGTAGTAATTGCAGTTACTAATAGTGATGAAAGAAATATG
CTTTGCTGCTTAGCAGCTAAGAGATTTGGAGCAAAACATACCATAGCAAGAATTAGAGATCCAGAATATGCAGAGGAGCT
TACAATGCTAAAAAGAGAGCTAGAAATTGATATGATTATTAATCCAGAAAAGGAAGCAGCTCTTGAAATTGCACAACTTA
TAAAATTTCCAACGGTATCTAGTGTAGAAAATTTTGCTCAGGGCAAAGTAGATTTAGTTAGTTTTAGATTAGGGAAAGAA
GACTTTATAGCAGGAAAATCTATTTCTGATATTGATTTAAAAAAATGCTCTGTATTATTTTGTGCTGTTGAAAGAGATGG
CAGAGTATTTATGCCCACAGGTGATTTTATACTTAAAAGTAATGACAAGGTATATGTTATAGGAGATCACGAGAATATAA
CATTGTTTTTGAAATATTTAGGTAAACATCAAAATAAAATTAAAAGTGTAATGGTAATAGGAGGAGGAAGAATAACCCAT
TATCTTACTAAATTAATTAATAAAGTTGGTGCTAATATAAAAATAGTAGAAAAAAATTATATTAAATGTAAAGATTTGAA
TGAAACATTGCCAGAAGCTATTATTATAAATGGAGATGGTACAGAACAAGAACTTTTAGAGTCAGAAAATTTAGAAGATG
TGGATGCTTTTATAGCCCTAACAGATCGTGATGAAGAAAATATTGTAGCGTCCCTATTTGCATTAAATGCTAATATACAT
AATGTTATAACGAAGATAACAAGAGTAAATTATAATCATATAGTTAAAAATATCGGAGTTGAAAGTGTTATAAGTCCTAA
AACTTTAACAGCCAATAAAATAATTACATATGTAAGAGGATTGAAGAATAAAAAAGGAAGTTTTATTGAAAACTTATATA
AAATAGTTGGAGAACAGGCAGAAGCAGTAGAATTTGCAGCTAATAGTACCACAAAATGTTTAAATGTAGCTTTAAAAGAT
ATAAAGATAAAAAAAGGAGTATTAATTGCCGCTATAGTTAGAAATAAAGATATAATAATTCCTAATGGTGAGGATTCCAT
AAAAGATGGTGATAATGTCATTATAGTAACGGAAGAAAATAATATAATGGATATTAATAATATACTAGAGGGAGGAAACT
TAATATGA

Upstream 100 bases:

>100_bases
GGTCTATGAATTAGTGTATTTTATAACCTTATTTTTTATTTTTTTATATATTTTTATATGTAATATATATCTAGTTAGTG
AAAGGACAGGTAAAGGAAAA

Downstream 100 bases:

>100_bases
ACTACCCAATAGTATTTAAAGTATTAGGAGATGTAATAAAATATGAAGCTTTAGTTATGATATTTCCTCTTATAGCGTCC
TTATATTATGGTGGCAAGGA

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog 1 [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MHVIIVGNGKVGYTLAKHLSQENNDVIVIDKNAEALQKAMDNLDVMCIKGNGTRVSVLKEAEISRADVVIAVTNSDERNM
LCCLAAKRFGAKHTIARIRDPEYAEELTMLKRELEIDMIINPEKEAALEIAQLIKFPTVSSVENFAQGKVDLVSFRLGKE
DFIAGKSISDIDLKKCSVLFCAVERDGRVFMPTGDFILKSNDKVYVIGDHENITLFLKYLGKHQNKIKSVMVIGGGRITH
YLTKLINKVGANIKIVEKNYIKCKDLNETLPEAIIINGDGTEQELLESENLEDVDAFIALTDRDEENIVASLFALNANIH
NVITKITRVNYNHIVKNIGVESVISPKTLTANKIITYVRGLKNKKGSFIENLYKIVGEQAEAVEFAANSTTKCLNVALKD
IKIKKGVLIAAIVRNKDIIIPNGEDSIKDGDNVIIVTEENNIMDINNILEGGNLI

Sequences:

>Translated_455_residues
MHVIIVGNGKVGYTLAKHLSQENNDVIVIDKNAEALQKAMDNLDVMCIKGNGTRVSVLKEAEISRADVVIAVTNSDERNM
LCCLAAKRFGAKHTIARIRDPEYAEELTMLKRELEIDMIINPEKEAALEIAQLIKFPTVSSVENFAQGKVDLVSFRLGKE
DFIAGKSISDIDLKKCSVLFCAVERDGRVFMPTGDFILKSNDKVYVIGDHENITLFLKYLGKHQNKIKSVMVIGGGRITH
YLTKLINKVGANIKIVEKNYIKCKDLNETLPEAIIINGDGTEQELLESENLEDVDAFIALTDRDEENIVASLFALNANIH
NVITKITRVNYNHIVKNIGVESVISPKTLTANKIITYVRGLKNKKGSFIENLYKIVGEQAEAVEFAANSTTKCLNVALKD
IKIKKGVLIAAIVRNKDIIIPNGEDSIKDGDNVIIVTEENNIMDINNILEGGNLI
>Mature_455_residues
MHVIIVGNGKVGYTLAKHLSQENNDVIVIDKNAEALQKAMDNLDVMCIKGNGTRVSVLKEAEISRADVVIAVTNSDERNM
LCCLAAKRFGAKHTIARIRDPEYAEELTMLKRELEIDMIINPEKEAALEIAQLIKFPTVSSVENFAQGKVDLVSFRLGKE
DFIAGKSISDIDLKKCSVLFCAVERDGRVFMPTGDFILKSNDKVYVIGDHENITLFLKYLGKHQNKIKSVMVIGGGRITH
YLTKLINKVGANIKIVEKNYIKCKDLNETLPEAIIINGDGTEQELLESENLEDVDAFIALTDRDEENIVASLFALNANIH
NVITKITRVNYNHIVKNIGVESVISPKTLTANKIITYVRGLKNKKGSFIENLYKIVGEQAEAVEFAANSTTKCLNVALKD
IKIKKGVLIAAIVRNKDIIIPNGEDSIKDGDNVIIVTEENNIMDINNILEGGNLI

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=32.7510917030568, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50376; Mature: 50376

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVIIVGNGKVGYTLAKHLSQENNDVIVIDKNAEALQKAMDNLDVMCIKGNGTRVSVLKE
CEEEEEECCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCCEEEEEEC
AEISRADVVIAVTNSDERNMLCCLAAKRFGAKHTIARIRDPEYAEELTMLKRELEIDMII
CCCCCCEEEEEEECCCCCCEEEEEEHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCEEEEE
NPEKEAALEIAQLIKFPTVSSVENFAQGKVDLVSFRLGKEDFIAGKSISDIDLKKCSVLF
CCCHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCHHHCCCCCCCCCCCCCEEEEE
CAVERDGRVFMPTGDFILKSNDKVYVIGDHENITLFLKYLGKHQNKIKSVMVIGGGRITH
EEEECCCEEEEECCCEEEECCCEEEEEECCCCEEEHHHHHHCHHCCEEEEEEECCCHHHH
YLTKLINKVGANIKIVEKNYIKCKDLNETLPEAIIINGDGTEQELLESENLEDVDAFIAL
HHHHHHHHHCCCEEEEECCCEEECCCCCCCCCEEEECCCCCHHHHHHCCCCCCCEEEEEE
TDRDEENIVASLFALNANIHNVITKITRVNYNHIVKNIGVESVISPKTLTANKIITYVRG
ECCCCHHHHEEHHHCCCCHHHHHHHHHHCCHHHHHHHCCHHHCCCCCCCCHHHHHHHHHH
LKNKKGSFIENLYKIVGEQAEAVEFAANSTTKCLNVALKDIKIKKGVLIAAIVRNKDIII
CCCCCCHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHEEEECCEEEEEEECCCEEEE
PNGEDSIKDGDNVIIVTEENNIMDINNILEGGNLI
ECCCCCCCCCCCEEEEECCCCEEEHHHHCCCCCCC
>Mature Secondary Structure
MHVIIVGNGKVGYTLAKHLSQENNDVIVIDKNAEALQKAMDNLDVMCIKGNGTRVSVLKE
CEEEEEECCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCCEEEEEEC
AEISRADVVIAVTNSDERNMLCCLAAKRFGAKHTIARIRDPEYAEELTMLKRELEIDMII
CCCCCCEEEEEEECCCCCCEEEEEEHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCEEEEE
NPEKEAALEIAQLIKFPTVSSVENFAQGKVDLVSFRLGKEDFIAGKSISDIDLKKCSVLF
CCCHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCHHHCCCCCCCCCCCCCEEEEE
CAVERDGRVFMPTGDFILKSNDKVYVIGDHENITLFLKYLGKHQNKIKSVMVIGGGRITH
EEEECCCEEEEECCCEEEECCCEEEEEECCCCEEEHHHHHHCHHCCEEEEEEECCCHHHH
YLTKLINKVGANIKIVEKNYIKCKDLNETLPEAIIINGDGTEQELLESENLEDVDAFIAL
HHHHHHHHHCCCEEEEECCCEEECCCCCCCCCEEEECCCCCHHHHHHCCCCCCCEEEEEE
TDRDEENIVASLFALNANIHNVITKITRVNYNHIVKNIGVESVISPKTLTANKIITYVRG
ECCCCHHHHEEHHHCCCCHHHHHHHHHHCCHHHHHHHCCHHHCCCCCCCCHHHHHHHHHH
LKNKKGSFIENLYKIVGEQAEAVEFAANSTTKCLNVALKDIKIKKGVLIAAIVRNKDIII
CCCCCCHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHEEEECCEEEEEEECCCEEEE
PNGEDSIKDGDNVIIVTEENNIMDINNILEGGNLI
ECCCCCCCCCCCEEEEECCCCEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8268235; 12125824 [H]