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The map label for this gene is dhaK [H]

Identifier: 148378967

GI number: 148378967

Start: 1074611

End: 1076371

Strand: Reverse

Name: dhaK [H]

Synonym: CBO0975

Alternate gene names: 148378967

Gene position: 1076371-1074611 (Counterclockwise)

Preceding gene: 148378968

Following gene: 148378966

Centisome position: 27.69

GC content: 33.33

Gene sequence:

>1761_bases
ATGAAAAAGATAATAAATAGACCTGAGACTGTAGTTATGGAGATGTGTAATGGAATAGCTATGGCACATCCTGAACTAGA
GTTTGTTAGAAAATATAAAGTAATGAAAAAAAAGAATATAAACAAAAATAAAGTTAGCTTAATTAGTGGTGGTGGAAGTG
GTCACGAACCAGCTCATGCCGGATTTATTGGAAAAGGAATGTTAGATGCAGCAGTATGCGGAGACATATTCGCTTCTCCC
TCTCAAATTCAAGTATATAAAGCTATAAAAGCTACAGCTAGCGAAAAAGGAACATTATTAATTATAAAAAACTATAGTGG
AGATATAATGAATTTTAAAAATGCTGCCCATTTAGCAAGTGAGGATGGTATTAAAGTTGACTATGTTAAAGTTGATGACG
ATATAGCTGTTGAAGATAGCTTATATACTGTAGGACGTAGAGGAGTTGCAGGTACTGTACTAGTTCATAAAATAGCAGGT
GCAGCTGCAGAATTAGGCTTTTCATTAGAAAAAGTTAAATCAATTGCTGAAAAAGCTGTTTCTAATGTTAGAAGCTTAGG
TTTTGCTTTCTCTTCTTGTACAGTTCCAGCTAAGAGAACTCCAACTTTTCAATTAGCTGAGGATGAAATGGAATTTGGTG
TTGGAATTCATGGCGAACCTGGAATAGTAAGAGAAAAAGTTGCTACAGCAGATGAATTAGCTAAAAAAATTGTTGATTCC
ATATTAAAAGACATGAAAATAGATGGATCAAATAATGAAGAAGTAGCGTTATTAATTAATGGTTTTGGTGCTACCCCTCT
ACAAGAATTATATCTATTTAATAATTCAGTTACTGCTGAGCTAGCAAAGAAAAATATAAAAATAAATAGAACATTTGTAG
GAAACTATATGACGAGTATAGATATGGAGGGAGCTTCAGTATCTATCATGAAATTAGATGATGAGCTTAAAGAATTACTA
TCAAAAGAAAGTGATACTCCTGCATTTAAAGTTTCAGGACCAGTTGAATCAGTTGAATATATCAGCTTAGAAGATAATAA
TGATATTGAAAATGAAGTTAGTTTTGATTTGGAAACTTGTGAGTGTCATAGCGAAATAAAAGATAAAAAAATCACTTTAG
ATAATATGATTTATATTATAGATAAGATGAGTGAAGTAATAATAGCAAATGAAGTTCACTTCTGTGAATTGGATTCTCAT
GCTGGTGATGGTGATTTCGGTATGAGTGTAGCAAAAGGCTTTAAACAATTAAAAAGAGAATGGAAACATATTCTTAAAGA
AGATAATATGAATATTGGTAAATTCTTAAACGAATGCTCTTTAATAATTATGGAACATTGTGGTGGAGCATCAGGCCCAA
TATGGGGATCAGCATTTAGATCCGCTGGAAAACAAGTTGGAGATAAAAAAGAATTATCAGTTTCAGATTTTGCTCAAATG
ATGCAGGCAGCTGTAAAAGGAATTCAAGCTACAGGAGAACGTTCTTTTGGAAGAGGAGCAGTAGTTGGAGATAAAACTTT
AATTGACGCATTAGTTCCTTGTGCTGATTTGTGGAGTGAGAGTGCTAATAACAATACTTCTATACATGAAGCCTTCCAAA
AAGGTGCCGCTGCAGCAGTTAAAGGTGCAAAAATGACTGAAGAAATAGTAGCTCGTATGGGTAGAGCAGGTACAGTTGGT
GAAAGAAGCATTGGTTACCCAGATGCAGGCGCTTATGGATTAGGAGTTATATTTACAGAAATATCAAATTCATTAAAATA
A

Upstream 100 bases:

>100_bases
TCTATGCCATTTAAGGTAACTCCAGAAGCAGTAGCAGCAGCAATAATAACAGCAGATACTTTAGGTAAAAAATATAAATC
AAATAAATAGAGGTGTAAAC

Downstream 100 bases:

>100_bases
GCCTTCTAATATTATAATAGCTCATACAATATTATAATTTAAAATTTAACCTAAAAACTCCAGTAAACATCTTATTTTTT
ACTGGGGTTTTTATTTTTAC

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASP
SQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAG
AAAELGFSLEKVKSIAEKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDS
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELL
SKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETCECHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSH
AGDGDFGMSVAKGFKQLKREWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAQM
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVG
ERSIGYPDAGAYGLGVIFTEISNSLK

Sequences:

>Translated_586_residues
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASP
SQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAG
AAAELGFSLEKVKSIAEKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDS
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELL
SKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETCECHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSH
AGDGDFGMSVAKGFKQLKREWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAQM
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVG
ERSIGYPDAGAYGLGVIFTEISNSLK
>Mature_586_residues
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASP
SQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAG
AAAELGFSLEKVKSIAEKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDS
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELL
SKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETCECHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSH
AGDGDFGMSVAKGFKQLKREWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAQM
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVG
ERSIGYPDAGAYGLGVIFTEISNSLK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=578, Percent_Identity=31.3148788927336, Blast_Score=279, Evalue=5e-75,
Organism=Escherichia coli, GI87081857, Length=352, Percent_Identity=43.1818181818182, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1787449, Length=179, Percent_Identity=31.2849162011173, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17565018, Length=583, Percent_Identity=31.0463121783877, Blast_Score=273, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6321055, Length=599, Percent_Identity=32.8881469115192, Blast_Score=237, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6323570, Length=593, Percent_Identity=32.8836424957842, Blast_Score=233, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 63297; Mature: 63297

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
GFIGKGMLDAAVCGDIFASPSQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLAS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHCC
EDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAGAAAELGFSLEKVKSIAEKAV
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDS
HHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSI
HHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEEECCHHEEE
DMEGASVSIMKLDDELKELLSKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETC
ECCCCEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCHHCCCHHHH
ECHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSHAGDGDFGMSVAKGFKQLKRE
HHHHHHCCCEEEHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
WKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAQM
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHH
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHH
KGAKMTEEIVARMGRAGTVGERSIGYPDAGAYGLGVIFTEISNSLK
HCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
GFIGKGMLDAAVCGDIFASPSQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLAS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHCC
EDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAGAAAELGFSLEKVKSIAEKAV
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDS
HHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSI
HHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEEECCHHEEE
DMEGASVSIMKLDDELKELLSKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETC
ECCCCEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCHHCCCHHHH
ECHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSHAGDGDFGMSVAKGFKQLKRE
HHHHHHCCCEEEHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
WKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAQM
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHH
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHH
KGAKMTEEIVARMGRAGTVGERSIGYPDAGAYGLGVIFTEISNSLK
HCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]