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The map label for this gene is fabZ

Identifier: 148360876

GI number: 148360876

Start: 602743

End: 603195

Strand: Direct

Name: fabZ

Synonym: LPC_2836

Alternate gene names: 148360876

Gene position: 602743-603195 (Clockwise)

Preceding gene: 148360877

Following gene: 148360875

Centisome position: 16.85

GC content: 39.29

Gene sequence:

>453_bases
ATGAACGAATCGATAGATATAAATCAAATTTTTACTTTGTTACCACACCGCTACCCATTTATTCTGGTTGATAGAGTGAT
AGATTACAAAGTAATGGAATATTTGATTGCAATCAAAAATGTGACTATTAATGAGAACTTCTTTACCGGGCATTTTCCAG
GAAATCCTATTATGCCTGGGGTACTAATGCTTGAGGCCTTAGCCCAAGCTTGTGGCATTTTAGCCAATTTGTCTCGCCAA
CCCAAAGAAGGGTATGAGTTTCTGCATTATTTTGCTGGTATTGACAATGCTCGGTTCAAGCAAGTAGTGATTCCCGGGGA
TCAGTTGCGATTAGAGGTGAGACTGGCTGGACAAAAAAGAGATTTTTGGCGTATGCACGGAGAAGCTTATATTGGTGATA
AATTGGCTTGTTCCGCAGACTTATTAAGCGCAGCAAAGGAAATTAAAAAGTGA

Upstream 100 bases:

>100_bases
GAAGTAACATTATTTTTGAAATTTTTAATTGATTAGAATGAGCTAAACCAAGATAATGAGCCATTTTGTAATGCAATAGG
CGATTAATGAGAACTAGGGT

Downstream 100 bases:

>100_bases
TAGATGAAAGAGCAATGATTCACCCATCGGCGAAGCTGGCAAGTGGAGTGTCAATAGGCCCTGGAACAGTGATAGGCGCT
GATGTTGAGATTGGTGAAAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQACGILANLSRQ
PKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLAGQKRDFWRMHGEAYIGDKLACSADLLSAAKEIKK

Sequences:

>Translated_150_residues
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQACGILANLSRQ
PKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLAGQKRDFWRMHGEAYIGDKLACSADLLSAAKEIKK
>Mature_150_residues
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPGVLMLEALAQACGILANLSRQ
PKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLAGQKRDFWRMHGEAYIGDKLACSADLLSAAKEIKK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=143, Percent_Identity=51.7482517482517, Blast_Score=152, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_LEGPA (Q5X7N3)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_122910.1
- ProteinModelPortal:   Q5X7N3
- SMR:   Q5X7N3
- STRING:   Q5X7N3
- GeneID:   3119298
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0572
- LegioList:   lpp0572
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   LPNE297246:LPP0572-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17100; Mature: 17100

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: ACT_SITE 51-51

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPG
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCEEECCCCCCCCCHH
VLMLEALAQACGILANLSRQPKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLAGQKR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCC
DFWRMHGEAYIGDKLACSADLLSAAKEIKK
HHHHHCCCEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNESIDINQIFTLLPHRYPFILVDRVIDYKVMEYLIAIKNVTINENFFTGHFPGNPIMPG
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCEEECCCCCCCCCHH
VLMLEALAQACGILANLSRQPKEGYEFLHYFAGIDNARFKQVVIPGDQLRLEVRLAGQKR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCC
DFWRMHGEAYIGDKLACSADLLSAAKEIKK
HHHHHCCCEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA