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The map label for this gene is rlmM [H]

Identifier: 148360742

GI number: 148360742

Start: 735199

End: 736062

Strand: Reverse

Name: rlmM [H]

Synonym: LPC_2691

Alternate gene names: 148360742

Gene position: 736062-735199 (Counterclockwise)

Preceding gene: 148360741

Following gene: 148360751

Centisome position: 20.58

GC content: 41.32

Gene sequence:

>864_bases
ATGGAACTGCCTTATCATTTCTCTACTGTCTATGTGTCAAAACCAGAGTTTATAGAAGCACTTTCTGAGGAGTTAGGCGA
GGTATCCAATAAAATAGGCTCTCTCGTTTTTTCTCCTCATCAGAAGCTTGATGTTTGTTTTGCACTGGATGTATGGCTTG
AACCTGAGATAGTAACCTTTCAATCCATTTCAGAAGCAGCAAAAATATTGAGGCAAGCCGGAAAATTCTGGTATTTGCAC
CCTGTTACTGAAATTCGCCGATCACGCTTGATTGAGGAACAACTTCGCAAGTGCCCATCACTAATGTCCCATTTTCCAGT
TACAAGTGACATTCCACCCATAGGTGTATTTAGTCTTCTTGATAGAAACACTCTGCTCTTTAGCGCCAAACGACTAAAAA
AATGGCCGGATGGACAATGTTATTTTATTGAAGACAAAGTCAATCCCCCAAACCGGGCTTATTTAAAATTATGGGAAGCC
TTGTTCCTGTTAAATAAATACCCTCTCCCTGGTGAAACAGTTTTAGATTTGGGCGCATCCCCGGGAGGTTGGACATATGT
GATGCAATCACTCGGAACCCAAGTCACTTCGGTCGACAAAGCAGAACTGGATACAAAAATCATGGCGCTTCCCAGAGTCA
GTTTTTTAAAGCAAAGCGCCTTTGCCTTAGATCCCGAACAACTCACAGAGTCTTATGACTGGGTACTTTCCGATGTTGCC
TGCTATCCTGACAGAGCCTACACCCTCATCAAAAAATGGATAGCATCAAAAAAAGCAAAACAGTTGATTTTTACCATCAA
ACTACAGGGACTAACTGACTTAAACACATCAAACGATTTCAATCCATACCTAATTCCAAAGTAA

Upstream 100 bases:

>100_bases
GTCAAGCGCTAATCGAGACAAAAATATAGAAAAAGAATACAAAATCGCCTAAATTACAGCATTTGACTTTGTCGCCATTA
ACCTGTGAGCGTTATTTATC

Downstream 100 bases:

>100_bases
TCAATCTGTTTTATACAAAACATGAAGTCACGTTTTTTTATCCAGTATAAACATAAGCAGGATTTAGTGATTATGTCTGC
AAAAATATCATAATGACGAG

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MELPYHFSTVYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEA
LFLLNKYPLPGETVLDLGASPGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGLTDLNTSNDFNPYLIPK

Sequences:

>Translated_287_residues
MELPYHFSTVYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEA
LFLLNKYPLPGETVLDLGASPGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGLTDLNTSNDFNPYLIPK
>Mature_287_residues
MELPYHFSTVYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTFQSISEAAKILRQAGKFWYLH
PVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLLDRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEA
LFLLNKYPLPGETVLDLGASPGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGLTDLNTSNDFNPYLIPK

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=128, Percent_Identity=28.125, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 32757; Mature: 32757

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPYHFSTVYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTF
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCEEHH
QSISEAAKILRQAGKFWYLHPVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLL
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEALFLLNKYPLPGETVLDLGAS
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
PGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGLTDLNTSNDFNPYLIPK
HCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MELPYHFSTVYVSKPEFIEALSEELGEVSNKIGSLVFSPHQKLDVCFALDVWLEPEIVTF
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCEEHH
QSISEAAKILRQAGKFWYLHPVTEIRRSRLIEEQLRKCPSLMSHFPVTSDIPPIGVFSLL
HHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DRNTLLFSAKRLKKWPDGQCYFIEDKVNPPNRAYLKLWEALFLLNKYPLPGETVLDLGAS
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
PGGWTYVMQSLGTQVTSVDKAELDTKIMALPRVSFLKQSAFALDPEQLTESYDWVLSDVA
CCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CYPDRAYTLIKKWIASKKAKQLIFTIKLQGLTDLNTSNDFNPYLIPK
HCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA