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The map label for this gene is alaS [H]

Identifier: 148360741

GI number: 148360741

Start: 736309

End: 736953

Strand: Reverse

Name: alaS [H]

Synonym: LPC_2690

Alternate gene names: 148360741

Gene position: 736953-736309 (Counterclockwise)

Preceding gene: 148360740

Following gene: 148360742

Centisome position: 20.61

GC content: 39.69

Gene sequence:

>645_bases
ATGGAAAAAATTTTTTGGTCTAATCCCTACCAGCATACACTCGATACCAAGATAATCTCAGTTAATGGCAACGAGATCCT
ATTGGAAAAAACCATCGCGTTTTCATTTTCAGGAGGACAGGAAAGCGATAGAGCATTCATCAATGGCCTTGAAGTACTCA
GTTCACGAATAGATGGAAATCTTATTTATTATACCCTGCCTGATGACCATAATCTTGCGCCCAATGATGTAATCACCATA
ACTATAGATTGGCCTCGAAGACACCGGCTGATGCGTCTTCATTTTGCAGCAGAACTGATTCTGGAACTTGTAACCAGAAC
CAGTATGCTTGAAAAAGTAGGAGCTCACATCTCGGAATCCAAAGCTCGAATAGATTTTAAAGCGAATTTTAATATCTCTT
CTATTTTTAGCCAGCTGCTTGATGAATATAATGCCATCATTAGACAAGATCTTGTTATCCATAAAGGATACCATGATGTG
ACAAATCAACGTCGGTTTTGGAAAATTGACGGTTTTGCTGAAGTGCCTTGTGGGGGAACACATGTTCATTCCACTTCAGA
AGTGGGTTTTATTCGTCTCAAACGCTCGCATCCTGGCAAAGCTATTGAACGCATTGAAATAACCCTGATGGATGATAGTA
GATAA

Upstream 100 bases:

>100_bases
CCTTATGTGGCAGTTTGCTTATTGTATTGATTCATATCAAAACAAGAGCTTATGCAGCTCCAGGATTTATAAAAAAGACT
TCATTGACAGGAGTGTAGCT

Downstream 100 bases:

>100_bases
TGCACCTCACAGATAAGCTGATTGTTTTGCTTTGGGGCAAGGTGAGAATGTTGTGGGGCATGGAGTTTATATACATTGAA
TGAACGTTGCTGAAACGTTT

Product: alanyl tRNA synthetase

Products: NA

Alternate protein names: AlaX-M; Alanyl-tRNA deacylase AlaX-M [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MEKIFWSNPYQHTLDTKIISVNGNEILLEKTIAFSFSGGQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDVITI
TIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHISESKARIDFKANFNISSIFSQLLDEYNAIIRQDLVIHKGYHDV
TNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSHPGKAIERIEITLMDDSR

Sequences:

>Translated_214_residues
MEKIFWSNPYQHTLDTKIISVNGNEILLEKTIAFSFSGGQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDVITI
TIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHISESKARIDFKANFNISSIFSQLLDEYNAIIRQDLVIHKGYHDV
TNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSHPGKAIERIEITLMDDSR
>Mature_214_residues
MEKIFWSNPYQHTLDTKIISVNGNEILLEKTIAFSFSGGQESDRAFINGLEVLSSRIDGNLIYYTLPDDHNLAPNDVITI
TIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHISESKARIDFKANFNISSIFSQLLDEYNAIIRQDLVIHKGYHDV
TNQRRFWKIDGFAEVPCGGTHVHSTSEVGFIRLKRSHPGKAIERIEITLMDDSR

Specific function: Functions in trans to edit the amino acid moiety from mischarged charged Gly-tRNA(Ala) and Ser-tRNA(Ala) [H]

COG id: COG2872

COG function: function code R; Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-M subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018165
- InterPro:   IPR018164
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF01411 tRNA-synt_2c; PF07973 tRNA_SAD [H]

EC number: NA

Molecular weight: Translated: 24550; Mature: 24550

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIFWSNPYQHTLDTKIISVNGNEILLEKTIAFSFSGGQESDRAFINGLEVLSSRIDGN
CCCEECCCCCCCCCCEEEEEECCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
LIYYTLPDDHNLAPNDVITITIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHISES
EEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KARIDFKANFNISSIFSQLLDEYNAIIRQDLVIHKGYHDVTNQRRFWKIDGFAEVPCGGT
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHCCCCEEEEECCEEECCCCCC
HVHSTSEVGFIRLKRSHPGKAIERIEITLMDDSR
EECCCCCCEEEEEECCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MEKIFWSNPYQHTLDTKIISVNGNEILLEKTIAFSFSGGQESDRAFINGLEVLSSRIDGN
CCCEECCCCCCCCCCEEEEEECCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
LIYYTLPDDHNLAPNDVITITIDWPRRHRLMRLHFAAELILELVTRTSMLEKVGAHISES
EEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KARIDFKANFNISSIFSQLLDEYNAIIRQDLVIHKGYHDVTNQRRFWKIDGFAEVPCGGT
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHCCCCEEEEECCEEECCCCCC
HVHSTSEVGFIRLKRSHPGKAIERIEITLMDDSR
EECCCCCCEEEEEECCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]