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The map label for this gene is 148360487

Identifier: 148360487

GI number: 148360487

Start: 1044833

End: 1045384

Strand: Reverse

Name: 148360487

Synonym: LPC_2427

Alternate gene names: NA

Gene position: 1045384-1044833 (Counterclockwise)

Preceding gene: 148360486

Following gene: 148360499

Centisome position: 29.23

GC content: 37.68

Gene sequence:

>552_bases
ATGCGTAAATTACCAAGACCTTTTTACGAACGTGATACCATTCTGGTTGCAAAAGAACTCTTAGGTAAATATTTGGTTCA
TCATGATGGATTGGAAGAGAAGATTGGGCGCATTGTAGAAGTCGAAGCCTACCTTGGGCAACATGATTTGGCCTGCCATT
CATCAAAAGGATTGACTAAAAGAACTAAAGTTATGTTTGGACCAGCAGGCTATGCGTATGTTTATCTAATTTATGGCATG
TATTATTGCATGAACGTAGTCACCGAAAAGGAGGGGATAGGTTCAGCAGTATTAATACGTGCCCTGGAGCCTATCAAAAA
CATTCAAGACAGAACTCAAGGACCAGGATTATTGTCCAAAGCTATGCGCATTGACTCCAAACTGAATCATCGTGATTTAT
TAAGCAATGATTTTTATATTGCTGAGCCAAACAGTCCAACTGATTTTACCATTATAGAAAAGCCCAGAATTGGGGTTCAT
TATGCTAAAGAATGGGCTAATGAGTTATTAAGGTTTTATATTAAAGACAATCCTTATATTTCGAAAACCTGA

Upstream 100 bases:

>100_bases
ACTGAATGTATCTGGGGTTGGGCAACATAAATTAGCTCGTTATGGCCATTATTTTCTCGAAGCCTTAAACGAATTTTCAG
AAGTCGAGTGAGATTCCGTT

Downstream 100 bases:

>100_bases
TTAGGCCTCGTGCATAACCTGTCTCTTTCATTTTATTGCCGCATTGCAAAGATTTCTGTGATGCTCAGGGTATGTAAAAA
GCGTATTATCGTATTAATAA

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MRKLPRPFYERDTILVAKELLGKYLVHHDGLEEKIGRIVEVEAYLGQHDLACHSSKGLTKRTKVMFGPAGYAYVYLIYGM
YYCMNVVTEKEGIGSAVLIRALEPIKNIQDRTQGPGLLSKAMRIDSKLNHRDLLSNDFYIAEPNSPTDFTIIEKPRIGVH
YAKEWANELLRFYIKDNPYISKT

Sequences:

>Translated_183_residues
MRKLPRPFYERDTILVAKELLGKYLVHHDGLEEKIGRIVEVEAYLGQHDLACHSSKGLTKRTKVMFGPAGYAYVYLIYGM
YYCMNVVTEKEGIGSAVLIRALEPIKNIQDRTQGPGLLSKAMRIDSKLNHRDLLSNDFYIAEPNSPTDFTIIEKPRIGVH
YAKEWANELLRFYIKDNPYISKT
>Mature_183_residues
MRKLPRPFYERDTILVAKELLGKYLVHHDGLEEKIGRIVEVEAYLGQHDLACHSSKGLTKRTKVMFGPAGYAYVYLIYGM
YYCMNVVTEKEGIGSAVLIRALEPIKNIQDRTQGPGLLSKAMRIDSKLNHRDLLSNDFYIAEPNSPTDFTIIEKPRIGVH
YAKEWANELLRFYIKDNPYISKT

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=200, Percent_Identity=36.5, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI62632765, Length=200, Percent_Identity=36.5, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI62632771, Length=200, Percent_Identity=36.5, Blast_Score=117, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: NA

Molecular weight: Translated: 21027; Mature: 21027

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLPRPFYERDTILVAKELLGKYLVHHDGLEEKIGRIVEVEAYLGQHDLACHSSKGLTK
CCCCCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHCCEEEHHHHHCCCCCCCCCCCCCCH
RTKVMFGPAGYAYVYLIYGMYYCMNVVTEKEGIGSAVLIRALEPIKNIQDRTQGPGLLSK
HHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
AMRIDSKLNHRDLLSNDFYIAEPNSPTDFTIIEKPRIGVHYAKEWANELLRFYIKDNPYI
HHHHHCCCCHHHHHCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
SKT
CCC
>Mature Secondary Structure
MRKLPRPFYERDTILVAKELLGKYLVHHDGLEEKIGRIVEVEAYLGQHDLACHSSKGLTK
CCCCCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHCCEEEHHHHHCCCCCCCCCCCCCCH
RTKVMFGPAGYAYVYLIYGMYYCMNVVTEKEGIGSAVLIRALEPIKNIQDRTQGPGLLSK
HHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
AMRIDSKLNHRDLLSNDFYIAEPNSPTDFTIIEKPRIGVHYAKEWANELLRFYIKDNPYI
HHHHHCCCCHHHHHCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
SKT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA