Click here to switch to the map view.

The map label for this gene is hupB [H]

Identifier: 148359403

GI number: 148359403

Start: 2160323

End: 2160601

Strand: Reverse

Name: hupB [H]

Synonym: LPC_1303

Alternate gene names: 148359403

Gene position: 2160601-2160323 (Counterclockwise)

Preceding gene: 148359404

Following gene: 148359402

Centisome position: 60.41

GC content: 39.78

Gene sequence:

>279_bases
ATGAATAAGAGTGAATTAGTTGATGCTATAGCAAGCGGTTCAGGTTTGACCAAAGCTGACGCAAGCAGAGTTCTTGAAAC
TTTTATGGCTACTGTAACTGATGTCTTAAAGAAAGGCGATCAAGTTGTAATACCTGGTTTTGGTTCTTTTTCAACAGGTA
ATCGTTCAGCACGTACTGGCAGAAACCCACAGACTGGAAAAACAATCCAAATTAAAGCGTCACGGGTTGCCAAATTTAAA
GCAGGTAAAAACCTGAAAGAAGCGGTACAACAAGCTTAA

Upstream 100 bases:

>100_bases
CTACTGGCGGGCTCTGCAAGGATGTACGAACTTGACTGGAGCAGTTGAATCTGTTTAAATCAGCTCCGGAATATGGATGA
TTAACTGTAAAGGGGAAAAG

Downstream 100 bases:

>100_bases
GTTTTCAGGGTGCTTAGCTCAGCTGGGAGAGCATCGCCCTTACAAGGCGAGGGTCGTAGGTTCGATCCCTACAGCACCCA
CCAAGAAATGGAGTGGTAGT

Product: hypothetical protein

Products: NA

Alternate protein names: HU-1; NS1 [H]

Number of amino acids: Translated: 92; Mature: 92

Protein sequence:

>92_residues
MNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTGRNPQTGKTIQIKASRVAKFK
AGKNLKEAVQQA

Sequences:

>Translated_92_residues
MNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTGRNPQTGKTIQIKASRVAKFK
AGKNLKEAVQQA
>Mature_92_residues
MNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTGRNPQTGKTIQIKASRVAKFK
AGKNLKEAVQQA

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=55.5555555555556, Blast_Score=105, Evalue=6e-25,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=50, Blast_Score=93, Evalue=3e-21,
Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=38.0434782608696, Blast_Score=75, Evalue=8e-16,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=38.4615384615385, Blast_Score=65, Evalue=6e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9683; Mature: 9683

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC
RNPQTGKTIQIKASRVAKFKAGKNLKEAVQQA
CCCCCCCEEEEEHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MNKSELVDAIASGSGLTKADASRVLETFMATVTDVLKKGDQVVIPGFGSFSTGNRSARTG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC
RNPQTGKTIQIKASRVAKFKAGKNLKEAVQQA
CCCCCCCEEEEEHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550432 [H]