Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 148359402

GI number: 148359402

Start: 2158191

End: 2160065

Strand: Reverse

Name: ppiD [H]

Synonym: LPC_1300

Alternate gene names: 148359402

Gene position: 2160065-2158191 (Counterclockwise)

Preceding gene: 148359403

Following gene: 148359398

Centisome position: 60.4

GC content: 35.79

Gene sequence:

>1875_bases
ATGTTGCAGAAGTTAAATGAACACATTCAGGGTGTAGTAGCGTGGTTAGTTATTATATTAATTGCTATTACCTTTACACT
TTTTGGTGTTGATTATTATTTTCAATCTCTACAAATATCCGATGCAAAGGTAATAGTTAATGATAAACCAATTACCATGC
AAGCGTTTGAAACGAACTACAGACGTACGCGTGCTCAGCAAGATTTACCACAGATGACTGCCGCTGATGAAAAAAATCTG
CAAAATCAAGTATTAAATCAAATGATAACGAATGAGGTGAGTATTCAGGCTGCCAGGAAATATGGATTTGAGGTTAGTCC
AGAACAAGCCAATGCGGCCATAGTGCAAATACCTCAATTCCAGGAGGATGGACATTTTTCAGCACAACGATATCAACAAG
CTTTGAGTGGAGCTTTGTTTACTCCAGAGACTTTCCAGAATGAAGTAAGGCAAGGCATGTTGCTTAATCAACAACGTTTT
GCGTTTATGGGAACATCATTTGCTTTATCAGATGAAATAAAGCGTTTTGTCAGATTGTACATGCAGACCAGGGATTATGA
TTATTTGACGGTACCTTCTGATCGCTTTGAACAACAGGCGAAGATTTCAGAAGATGATATCAAGAGTTATTATAACCAAC
ACCATAAAAAATTTATGACTTCAGAGCAAGTTACATTGGATTATGTGCTTTTGACTATGCATGATATCAAGTCACAAATA
AAGATATCACCCGACGAAATTAAAAGCTATTATGAAGAAAACAAAAGTAACTACCTAACTCCTGCTCAATGGCGGGTTGC
CCATATTTTATTTGCAGTTCCAGAAAATGCCACCAAGGAAGAACAAGATTCAATTAAGCAAAAAGCCGATGAGGTTTATA
GCGATTTAAAAAAGCATCCAGAACAATTTGATAAATATGTTGCTTCCAAATCTGATGACAAGTTATCTATAGCCAATAAG
GGTATTCTTCCCTGGATTACTGGCGGGCAAAATGAATATGGCAGAGTACTTTCCAATTTAACTAGACCAGGGGAAATTTC
TACACCAGTACAAACAAAATATGGTTATGAAATTTTTAAGCTGATTGCTTACAAACCAGTTACAACTAAATCTTTGCAAG
AAGTTGAAAACATTATAAAGGATCAACTAACCAGCGATATGGCTCAGGCAAAATACGCTCAAGTTTTAGAGCAATTAACA
GATTTAAGTTATCAAACTCCTGATTCACTTGATCCGGTTTTGGATTCATTAAAGCTGAAAATGCAACATACAGAGCCTTT
TTCTCGTGATGGTGGCAAGCAACCTATTACCAAAAATAAGCAGGTTATCCATGCAGCATTCAGCACTGATGTTTTAGAAC
TAGGGAATAATAGCGAGCCTATACAGATTGATAATGACTCTGTAATAGTTTTACGAGTGAAGAAACATATACCTTCAAGA
GAACAAACCTTGGATGAAGTGCGAGATCAGATTAAAAAAATACTTGCAAAACAGTATGGGGATGCTAAAGCAAAAGAAAT
TGGTAGTAGTTTGCTTCACCCCGTTGAAGATAAGCAACAGCAGGAATTAATCGCTAACAATCAATTCGAATGGCATTCTG
TAGAGAATGCTTCCAGGGATAGTGATAAAGCAAATTCTTTAATTAATGATTTAGCATTTAATTTATTACGTCCAGAAAGC
CGAGACGGAGTAATTTTAGACAACGGCGATTATGTTGTTGTTAAATTAAAACGAATTAATGATGGAAAATTAAGCTCTCT
GGATCAAGAGCAAAGAGATAGCTTGATACAGCAAATAGAAGCTAGCTATGGAATGATGGATTATGATTTATATGTTAATA
ACTTGCTTCATCATGCGAAAATAGAAAGGAAATAG

Upstream 100 bases:

>100_bases
ACTCCGCCAGATAAACGCGCTGAAAGGCGCGTTTTTTTTATCAGCTTATGGTAGAATCGGTTTCATCAAGCATTGTTAAT
ATCAAAATGGATCTCGGGAC

Downstream 100 bases:

>100_bases
GATAAGAAAATGGCTGTTCCTTACGAAATTAAGGGATGGCCAGATATCGAGAATTCTTCAGTTTTTGCCTATAGTTTTTC
TCTGTGAGGCTTTTTCAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSLQISDAKVIVNDKPITMQAFETNYRRTRAQQDLPQMTAADEKNL
QNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQFQEDGHFSAQRYQQALSGALFTPETFQNEVRQGMLLNQQRF
AFMGTSFALSDEIKRFVRLYMQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLTMHDIKSQI
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYSDLKKHPEQFDKYVASKSDDKLSIANK
GILPWITGGQNEYGRVLSNLTRPGEISTPVQTKYGYEIFKLIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLT
DLSYQTPDSLDPVLDSLKLKMQHTEPFSRDGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EQTLDEVRDQIKKILAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRDSDKANSLINDLAFNLLRPES
RDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIEASYGMMDYDLYVNNLLHHAKIERK

Sequences:

>Translated_624_residues
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSLQISDAKVIVNDKPITMQAFETNYRRTRAQQDLPQMTAADEKNL
QNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQFQEDGHFSAQRYQQALSGALFTPETFQNEVRQGMLLNQQRF
AFMGTSFALSDEIKRFVRLYMQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLTMHDIKSQI
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYSDLKKHPEQFDKYVASKSDDKLSIANK
GILPWITGGQNEYGRVLSNLTRPGEISTPVQTKYGYEIFKLIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLT
DLSYQTPDSLDPVLDSLKLKMQHTEPFSRDGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EQTLDEVRDQIKKILAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRDSDKANSLINDLAFNLLRPES
RDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIEASYGMMDYDLYVNNLLHHAKIERK
>Mature_624_residues
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSLQISDAKVIVNDKPITMQAFETNYRRTRAQQDLPQMTAADEKNL
QNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQFQEDGHFSAQRYQQALSGALFTPETFQNEVRQGMLLNQQRF
AFMGTSFALSDEIKRFVRLYMQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLTMHDIKSQI
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYSDLKKHPEQFDKYVASKSDDKLSIANK
GILPWITGGQNEYGRVLSNLTRPGEISTPVQTKYGYEIFKLIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLT
DLSYQTPDSLDPVLDSLKLKMQHTEPFSRDGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EQTLDEVRDQIKKILAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRDSDKANSLINDLAFNLLRPES
RDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIEASYGMMDYDLYVNNLLHHAKIERK

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=639, Percent_Identity=25.8215962441315, Blast_Score=169, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71644; Mature: 71644

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSLQISDAKVIVNDKPITMQAFETNY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCEEHHHHHHH
RRTRAQQDLPQMTAADEKNLQNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQF
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
QEDGHFSAQRYQQALSGALFTPETFQNEVRQGMLLNQQRFAFMGTSFALSDEIKRFVRLY
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHH
MQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLTMHDIKSQI
HHHCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYSDLKKHP
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCH
EQFDKYVASKSDDKLSIANKGILPWITGGQNEYGRVLSNLTRPGEISTPVQTKYGYEIFK
HHHHHHHHCCCCCCEECCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLTDLSYQTPDSLDPVLDSLKLK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
MQHTEPFSRDGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
HHCCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHCCCH
EQTLDEVRDQIKKILAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
SDKANSLINDLAFNLLRPESRDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIE
CHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
ASYGMMDYDLYVNNLLHHAKIERK
HHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSLQISDAKVIVNDKPITMQAFETNY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCEEHHHHHHH
RRTRAQQDLPQMTAADEKNLQNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQF
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
QEDGHFSAQRYQQALSGALFTPETFQNEVRQGMLLNQQRFAFMGTSFALSDEIKRFVRLY
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHH
MQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLTMHDIKSQI
HHHCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYSDLKKHP
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCH
EQFDKYVASKSDDKLSIANKGILPWITGGQNEYGRVLSNLTRPGEISTPVQTKYGYEIFK
HHHHHHHHCCCCCCEECCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLTDLSYQTPDSLDPVLDSLKLK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
MQHTEPFSRDGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
HHCCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHCCCH
EQTLDEVRDQIKKILAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
SDKANSLINDLAFNLLRPESRDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIE
CHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
ASYGMMDYDLYVNNLLHHAKIERK
HHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]