Click here to switch to the map view.

The map label for this gene is iolCB [H]

Identifier: 148359187

GI number: 148359187

Start: 1894378

End: 1896264

Strand: Reverse

Name: iolCB [H]

Synonym: LPC_1081

Alternate gene names: 148359187

Gene position: 1896264-1894378 (Counterclockwise)

Preceding gene: 148359188

Following gene: 148359186

Centisome position: 53.02

GC content: 38.37

Gene sequence:

>1887_bases
ATGAAACAGTTTCCCGGATTTTATTTTGATAAGAATAGAGCAATCGATTTGATTTGTATGGGACGCGTAGCAGTTGATCT
CTACGCGGAGCAAATAGGATTGGATTTGAAGGATGTTGCAAGCTTTAAAAAATATTTGGGTGGTTGTGCAGGAAATATTG
CCGTTGGAGCTGCCCGATTAGGATTAAAAAGCCAGATGTTTTCCTGTGTTGGCTCAGATGAGTTAGGTAAGTTTCTGAAA
GAAGAATTGGAACGTGAGGGAGTTAATATTGAGTTATTATCGGAAACAGATAATCATTTAACTGGCCTTGTACTTTTGGG
CATTAAGCCTCCCTCCAATTTCCCTCTGCTTTTTTATCGTAATGATTGCGCAGATATGCAGATTAAATCAGATCAAATTA
GTTTTACTGATTTAAAAAATGCAAAGGCATTATTGATAACGGGCACTGGTTTATCCACAGAATCAATGAAAAATACTACC
CTGGAAGTAGTTCATTTAGCCCGAAAAGCAGAAACGACAATAGTTTTTGATCTCGATTATAGACCTGTCCTTTGGCGGTT
AACTGTGATTGGTAATGGGGAAAGTCGTTATTGCCAGAATGAATATGTAACTCAAGTGTATCAACAAGTTTTGCCTTTAT
GCGATTTGATTGTTGGGACTGAAGAGGAAATATGTATTGCAGGCGGTTCGAATGATATTGAAGTTTCATTAATCAATATC
AGGCAGCGAACCGATGCGCCAATAGTTGTTAAATTAGGAGAGAAGGGTGCTCGTGTTCATTTTGGAACAGACAAAGGTCT
ATTACAGGCAAAATCTTTTCCTGTTGAAGTATTGAATGTTTTGGGAGCAGGTGATGGTTTTATGTCCGGCCTTTTATCTG
GTTTGCTGCAAGGGAAATCATGGGAGCAAGCAGTAACCTATGCTAATGCTTGTGGTGCCTTGGTCGTGACTCGTCATGGT
TGCGCTCCTGCAATTCCATACAAGGAAGAATTGGACTATTTTATTCAAGAATATGAGCATGATCCTGAAATATGGAGCAG
CTCTCAGTTAACACAACTGCATGAGAAATTAAGTAAAAATCAAAAGACACAGTTGCTTATTAAAAATCCATGTGGATTTG
CCGATGGTTTAAATTCGATTGTAACGATGCAAGATTCACCTACAGCAATGAGTTTTAGTTCTCTTAAATTAAATAAGGGG
CAAAGCCATCAATTTAACTCAAGTTATGAATTTGCAGCCCTCTTAATGACAGGAAAAGTTGTTTTCCAGTATGGCTCTTA
TAGCCAGGAGGTTGAACGTACAGATTATTTTTCTCAATCACCGTATGTCTTGCACTGCTCAAAGAATGAAGTAAGTTCAG
TAATCGCTCTGACTGATTGTGAAATTTTATTAATGGAAACGGAAAACGAAAATTTATTTTCTCCGATTTTATTTGATGCA
TCCAATATGCTTGAGCTAGACAATAGGGGAGAAGGAGTTCTTGAAAATACTTCATATCGACTTGTCAGAACGGTATTTGA
TAAACGAAACAGACCCGAATCTAATTTGGTAGTTGGGGAAATTATTACGTTTCAAGGGCGTTGGTCAAGTTATCCTTCAC
ATTATCATCAACAACCTGAAATTTACCATTACAGGTTTTCAGAGCCTCAAGGCTATGCTTTTGGCGAAAATGGTAAAGAG
GTGATGCGAATTGAACACTATGATACCTACCAGATTGCCAATAATCAGGAACATGCTCATTGTGCAGCGCCCGGTTATGC
ACTTTATACACTGTGGTTTATCCGGCATTTAAATAATAACGCATATACCTTGCCTACCTTCATAAAAGACCATGAATGGA
CAAGGACAAGCAGGGCAAATTTAAGAGCATGGCAACAGAAACAGTAG

Upstream 100 bases:

>100_bases
CCCGTTTCAGGATTGGATGGACTACAAGCCTTGCGCATTGCAAAAGCAGCGAAACAATCTTTAGAAACGCATCTCCCGGT
AGTATTGAGTTGAGGCCGCT

Downstream 100 bases:

>100_bases
TAATCCTTATCTGCAGTATGATTTTGAGAGTTAAATAAATGAAGATTAAATTAACTATGGCTCAGGCCCTATTAAGATTT
TTAGCTAATCAGTATGTCGT

Product: IolC/IolB transferase kinase protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARLGLKSQMFSCVGSDELGKFLK
EELEREGVNIELLSETDNHLTGLVLLGIKPPSNFPLLFYRNDCADMQIKSDQISFTDLKNAKALLITGTGLSTESMKNTT
LEVVHLARKAETTIVFDLDYRPVLWRLTVIGNGESRYCQNEYVTQVYQQVLPLCDLIVGTEEEICIAGGSNDIEVSLINI
RQRTDAPIVVKLGEKGARVHFGTDKGLLQAKSFPVEVLNVLGAGDGFMSGLLSGLLQGKSWEQAVTYANACGALVVTRHG
CAPAIPYKEELDYFIQEYEHDPEIWSSSQLTQLHEKLSKNQKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKG
QSHQFNSSYEFAALLMTGKVVFQYGSYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA
SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPEIYHYRFSEPQGYAFGENGKE
VMRIEHYDTYQIANNQEHAHCAAPGYALYTLWFIRHLNNNAYTLPTFIKDHEWTRTSRANLRAWQQKQ

Sequences:

>Translated_628_residues
MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARLGLKSQMFSCVGSDELGKFLK
EELEREGVNIELLSETDNHLTGLVLLGIKPPSNFPLLFYRNDCADMQIKSDQISFTDLKNAKALLITGTGLSTESMKNTT
LEVVHLARKAETTIVFDLDYRPVLWRLTVIGNGESRYCQNEYVTQVYQQVLPLCDLIVGTEEEICIAGGSNDIEVSLINI
RQRTDAPIVVKLGEKGARVHFGTDKGLLQAKSFPVEVLNVLGAGDGFMSGLLSGLLQGKSWEQAVTYANACGALVVTRHG
CAPAIPYKEELDYFIQEYEHDPEIWSSSQLTQLHEKLSKNQKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKG
QSHQFNSSYEFAALLMTGKVVFQYGSYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA
SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPEIYHYRFSEPQGYAFGENGKE
VMRIEHYDTYQIANNQEHAHCAAPGYALYTLWFIRHLNNNAYTLPTFIKDHEWTRTSRANLRAWQQKQ
>Mature_628_residues
MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARLGLKSQMFSCVGSDELGKFLK
EELEREGVNIELLSETDNHLTGLVLLGIKPPSNFPLLFYRNDCADMQIKSDQISFTDLKNAKALLITGTGLSTESMKNTT
LEVVHLARKAETTIVFDLDYRPVLWRLTVIGNGESRYCQNEYVTQVYQQVLPLCDLIVGTEEEICIAGGSNDIEVSLINI
RQRTDAPIVVKLGEKGARVHFGTDKGLLQAKSFPVEVLNVLGAGDGFMSGLLSGLLQGKSWEQAVTYANACGALVVTRHG
CAPAIPYKEELDYFIQEYEHDPEIWSSSQLTQLHEKLSKNQKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKG
QSHQFNSSYEFAALLMTGKVVFQYGSYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA
SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPEIYHYRFSEPQGYAFGENGKE
VMRIEHYDTYQIANNQEHAHCAAPGYALYTLWFIRHLNNNAYTLPTFIKDHEWTRTSRANLRAWQQKQ

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=294, Percent_Identity=24.4897959183673, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790193, Length=305, Percent_Identity=22.9508196721311, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 70699; Mature: 70699

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARL
CCCCCCCEECCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHH
GLKSQMFSCVGSDELGKFLKEELEREGVNIELLSETDNHLTGLVLLGIKPPSNFPLLFYR
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCCCEEEEE
NDCADMQIKSDQISFTDLKNAKALLITGTGLSTESMKNTTLEVVHLARKAETTIVFDLDY
CCCCCCEEECCCEEEEECCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHCCEEEEEEECC
RPVLWRLTVIGNGESRYCQNEYVTQVYQQVLPLCDLIVGTEEEICIAGGSNDIEVSLINI
CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEE
RQRTDAPIVVKLGEKGARVHFGTDKGLLQAKSFPVEVLNVLGAGDGFMSGLLSGLLQGKS
ECCCCCCEEEEECCCCCEEEECCCCCCEECCCCCHHHHHHHCCCCHHHHHHHHHHHCCCC
WEQAVTYANACGALVVTRHGCAPAIPYKEELDYFIQEYEHDPEIWSSSQLTQLHEKLSKN
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
QKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKGQSHQFNSSYEFAALLMTGKV
CCEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEECEE
VFQYGSYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA
EEEECCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCHHEECC
SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPE
CCEEEECCCCCCCEECCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHCCCCC
IYHYRFSEPQGYAFGENGKEVMRIEHYDTYQIANNQEHAHCAAPGYALYTLWFIRHLNNN
EEEEEECCCCCCEECCCCCEEEEEECCCEEEECCCCCCCEECCCCHHHHHHHHHHHHCCC
AYTLPTFIKDHEWTRTSRANLRAWQQKQ
CEECCHHHCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARL
CCCCCCCEECCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHH
GLKSQMFSCVGSDELGKFLKEELEREGVNIELLSETDNHLTGLVLLGIKPPSNFPLLFYR
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCCCEEEEE
NDCADMQIKSDQISFTDLKNAKALLITGTGLSTESMKNTTLEVVHLARKAETTIVFDLDY
CCCCCCEEECCCEEEEECCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHCCEEEEEEECC
RPVLWRLTVIGNGESRYCQNEYVTQVYQQVLPLCDLIVGTEEEICIAGGSNDIEVSLINI
CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEE
RQRTDAPIVVKLGEKGARVHFGTDKGLLQAKSFPVEVLNVLGAGDGFMSGLLSGLLQGKS
ECCCCCCEEEEECCCCCEEEECCCCCCEECCCCCHHHHHHHCCCCHHHHHHHHHHHCCCC
WEQAVTYANACGALVVTRHGCAPAIPYKEELDYFIQEYEHDPEIWSSSQLTQLHEKLSKN
HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
QKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKGQSHQFNSSYEFAALLMTGKV
CCEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEECEE
VFQYGSYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA
EEEECCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCHHEECC
SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPE
CCEEEECCCCCCCEECCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHCCCCC
IYHYRFSEPQGYAFGENGKEVMRIEHYDTYQIANNQEHAHCAAPGYALYTLWFIRHLNNN
EEEEEECCCCCCEECCCCCEEEEEECCCEEEECCCCCCCEECCCCHHHHHHHHHHHHCCC
AYTLPTFIKDHEWTRTSRANLRAWQQKQ
CEECCHHHCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]