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The map label for this gene is clpX

Identifier: 148284535

GI number: 148284535

Start: 918454

End: 919707

Strand: Direct

Name: clpX

Synonym: OTBS_0948

Alternate gene names: 148284535

Gene position: 918454-919707 (Clockwise)

Preceding gene: 148284520

Following gene: 148284540

Centisome position: 43.18

GC content: 32.54

Gene sequence:

>1254_bases
ATGGCTAAAAAAATTGACAATAAAGCATTGTCCTGTTCGTTTTGTTGTAAAAATCAAAATGAAGTTAAAAAATTAATAGC
TGGCTTTTCAGGCTTTATTTGCGATGAATGCATTGAGCTATGTATTCATCTAATTGAGGAAGAGCGTAAATCTAATTTAG
CTATATCTAACTATTCAAAATTACCACCAAAAAAAATATATGAAGCAATTAATGCTCATGTTGTAGGGCAGCAGCAGGCT
GCTAAAATTCTAGCTGTGGCTGTTTATATTCAGTGTATAAGGTTTGAGCATCGAGAATTAGCTGATCTTGTAGCAAAATC
TAATGTGTTGCTTATTGGACCTACTGGTTGCGGTAAGACTTTAATAGCACAAACTTTAGCAAAGATAATTAATGTACCAT
TTGCAATGGCTGATGCTACTTCGTTAACTGAAGCGGGCTATGTAGGAGAGGATGTTGAGAATATTATTCTAAGACTATTA
CAAGCAGCAGATTTTAATGTTGAAAGAGCCCAAAAAGGGATCATATATATTGATGAAATAGATAAAATTGCCCGCAAGTC
AGAAAACCCTTCTATTACAAGAGATGTATCTGGCGAAGGAGTACAGCAAGCTTTATTAAAAATTATGGAGGGAACTATTG
CATTGGTGCCTCCTCAAGGAGGGAGAAAGCATCCTCAGCAAGATTTTATTCAAATAGATACAACTAATATGTTATTCATA
TGCGGAGGTGCTTTTACTGGAATTGAAAAAATTATTGAAGCCAGAACTTCACAAAGTACTATAGGATTTGAAGCAACAGT
GAAATCAAAACATGATCAAGATTATAATCAAATTCTGAATAATCTTGAAGCTGATGATTTAACTAAATTTGGATTAATTC
CTGAATTTTTGGGTAGATTACCTGTAATTGCTACATTATCTGATCTAAATCAACAGTCTTTAGTAGATATATTAACAAAA
CCTAAAAATGCTTTAGTAAAGCAATATCAGAAACTTTTTGAACTTGATGGAGCAGAGTTGATTTTTGAAGAAGAAGCGCT
AATAGCAATTGCCCAAAAGGCATTAGCAAAAAAAACTGGTGCTAGAGGGTTACGTGCAATTTTAGAATGCGTATTATTAG
ATACAATGTTTGAGTTAAGCAATCTTAAAAATATGCAAGTAATAATCACAGCTGATATTGTCAAAAATAATCTAAAGCCT
ATTATAAAGCCTAAACTGCAAAAAAAATCAGTGAAAAAAAAAGTTACAGCTTAA

Upstream 100 bases:

>100_bases
CTTGAAAATTATGATTTATATATATATAGTAATCAAAAGGTAGTTTATTAAAAATCAAAATATAAGACCACTATAAATTT
CTAAATAACAATATTAAGTT

Downstream 100 bases:

>100_bases
ACAAATCAGTGCAATTTAGTTAAGACAATTTCTTTCTTATGGTTTTGGCAAAGTAAGAAGAAAGCTTTTTTAAGATATAG
CTTTTTTAATAAAGCTGAAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSKLPPKKIYEAINAHVVGQQQA
AKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKTLIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLL
QAADFNVERAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQDFIQIDTTNMLFI
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRLPVIATLSDLNQQSLVDILTK
PKNALVKQYQKLFELDGAELIFEEEALIAIAQKALAKKTGARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKP
IIKPKLQKKSVKKKVTA

Sequences:

>Translated_417_residues
MAKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSKLPPKKIYEAINAHVVGQQQA
AKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKTLIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLL
QAADFNVERAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQDFIQIDTTNMLFI
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRLPVIATLSDLNQQSLVDILTK
PKNALVKQYQKLFELDGAELIFEEEALIAIAQKALAKKTGARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKP
IIKPKLQKKSVKKKVTA
>Mature_416_residues
AKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSKLPPKKIYEAINAHVVGQQQAA
KILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKTLIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLLQ
AADFNVERAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQDFIQIDTTNMLFIC
GGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRLPVIATLSDLNQQSLVDILTKP
KNALVKQYQKLFELDGAELIFEEEALIAIAQKALAKKTGARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKPI
IKPKLQKKSVKKKVTA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=319, Percent_Identity=48.2758620689655, Blast_Score=295, Evalue=5e-80,
Organism=Escherichia coli, GI1786642, Length=413, Percent_Identity=58.1113801452784, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=42.4528301886792, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=44.8717948717949, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI71982905, Length=297, Percent_Identity=46.1279461279461, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=392, Percent_Identity=36.2244897959184, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=38.1526104417671, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319704, Length=415, Percent_Identity=36.6265060240964, Blast_Score=230, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24648289, Length=312, Percent_Identity=47.7564102564103, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24648291, Length=312, Percent_Identity=47.7564102564103, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_ORITB (A5CDP2)

Other databases:

- EMBL:   AM494475
- RefSeq:   YP_001248625.1
- ProteinModelPortal:   A5CDP2
- STRING:   A5CDP2
- GeneID:   5219535
- GenomeReviews:   AM494475_GR
- KEGG:   ots:OTBS_0948
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   OTSU357244:OTBS_0948-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45976; Mature: 45845

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSK
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
LPPKKIYEAINAHVVGQQQAAKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKT
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
LIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLLQAADFNVERAQKGIIYIDEI
HHHHHHHHHHCCCHHHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEHHH
DKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQDFIQIDTTNMLFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHCCEEEECCCEEEE
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRL
ECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHCCC
PVIATLSDLNQQSLVDILTKPKNALVKQYQKLFELDGAELIFEEEALIAIAQKALAKKTG
CHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHC
ARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKPIIKPKLQKKSVKKKVTA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSK
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
LPPKKIYEAINAHVVGQQQAAKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKT
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
LIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLLQAADFNVERAQKGIIYIDEI
HHHHHHHHHHCCCHHHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEHHH
DKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQDFIQIDTTNMLFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHCCEEEECCCEEEE
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRL
ECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHCCC
PVIATLSDLNQQSLVDILTKPKNALVKQYQKLFELDGAELIFEEEALIAIAQKALAKKTG
CHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHC
ARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKPIIKPKLQKKSVKKKVTA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA