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The map label for this gene is pyrR

Identifier: 148267689

GI number: 148267689

Start: 1302361

End: 1302888

Strand: Direct

Name: pyrR

Synonym: SaurJH9_1257

Alternate gene names: 148267689

Gene position: 1302361-1302888 (Clockwise)

Preceding gene: 148267688

Following gene: 148267690

Centisome position: 44.81

GC content: 34.09

Gene sequence:

>528_bases
ATGTCTGAACGTATTATAATGGATGATGCCGCAATACAACGTACAGTGACGAGAATCGCTCACGAAATTTTGGAGTATAA
CAAAGGTACTGATAATTTAATTCTTTTAGGTATCAAAACAAGAGGTGAATATTTAGCGAATCGTATACAAGATAAAATTC
ATCAAATTGAGCAACAACGTATACCTACTGGAACAATTGATATTACATACTTTAGAGATGATATAGAGCACATGTCATCA
CTTACGACAAAAGACGCAATAGACATCGACACAGATATTACAGATAAAGTAGTCATCATTATTGATGATGTGCTGTATAC
TGGTCGAACGGTTCGTGCTTCACTTGATGCTATTTTGCTAAATGCTAGACCTATTAAAATTGGTTTAGCTGCTTTGGTTG
ATCGAGGACATCGTGAGTTACCAATTCGAGCAGATTTTGTTGGTAAAAATATACCTACTTCTAAAGAGGAAACGGTAAGT
GTCTATTTAGAAGAAATGGATCAAAGAAATGCAGTTATAATTAAATAA

Upstream 100 bases:

>100_bases
ACGATTCTTCTATGTAAATAGGCTGATTGTATATACTAAACCTCATGTCGATATTAAAGACATGAGGTTTTTTGTTTCTA
AATTTTGAAAGGGTGAGAAT

Downstream 100 bases:

>100_bases
TACCCCTTTTAATTCAGTACGAGAGACTGAAAAAGGTGGGGGAGTTGAATGATAAATAAGTTTTCATATGCTTGTTTATC
TAATAATACCCTCATGTTCG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSS
LTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVS
VYLEEMDQRNAVIIK

Sequences:

>Translated_175_residues
MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSS
LTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVS
VYLEEMDQRNAVIIK
>Mature_174_residues
SERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSSL
TTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVSV
YLEEMDQRNAVIIK

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_STAA1 (A7X1E5)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441778.1
- ProteinModelPortal:   A7X1E5
- SMR:   A7X1E5
- STRING:   A7X1E5
- EnsemblBacteria:   EBSTAT00000004231
- GeneID:   5561053
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1188
- eggNOG:   COG2065
- GeneTree:   EBGT00050000024018
- HOGENOM:   HBG641958
- OMA:   IAHEVLE
- ProtClustDB:   PRK05205
- BioCyc:   SAUR418127:SAHV_1188-MONOMER
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 19855; Mature: 19724

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQR
CCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHC
IPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILL
CCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHCCCHHHHHHHEEEE
NARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVSVYLEEMDQRNAVIIK
CCCCHHHHHHHHHCCCCCCCCEEHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQR
CCCEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHC
IPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILL
CCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHCCCHHHHHHHEEEE
NARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVSVYLEEMDQRNAVIIK
CCCCHHHHHHHHHCCCCCCCCEEHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA