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The map label for this gene is pdhB [H]

Identifier: 148267587

GI number: 148267587

Start: 1196536

End: 1197513

Strand: Direct

Name: pdhB [H]

Synonym: SaurJH9_1154

Alternate gene names: 148267587

Gene position: 1196536-1197513 (Clockwise)

Preceding gene: 148267586

Following gene: 148267588

Centisome position: 41.16

GC content: 38.34

Gene sequence:

>978_bases
ATGGCACAAATGACAATGGTTCAAGCGATTAATGATGCGCTTAAAACTGAACTTAAAAATGACCAAGATGTTTTAATTTT
TGGTGAAGACGTTGGTGTTAACGGCGGTGTTTTCCGTGTTACTGAAGGACTACAAAAAGAATTTGGTGAAGATAGAGTAT
TCGATACACCTTTAGCTGAATCAGGTATTGGTGGTTTAGCGATGGGTCTTGCAGTTGAAGGATTCCGTCCGGTTATGGAA
GTACAATTCTTAGGTTTCGTATTCGAAGTATTTGATGCGATTGCTGGACAAATTGCACGTACTCGTTTCCGTTCAGGCGG
TACTAAAACTGCACCTGTAACAATTCGTAGCCCATTTGGTGGTGGCGTACACACACCAGAATTACACGCAGATAACTTAG
AAGGTATTTTAGCTCAATCTCCAGGTCTAAAGGTTGTTATTCCTTCAGGCCCATACGATGCGAAAGGTTTATTAATTTCT
TCTATTAGAAGTAATGACCCAGTCGTATACTTAGAGCATATGAAATTGTATCGTTCATTCCGTGAAGAAGTACCTGAAGA
AGAATATACAATTGACATTGGTAAGGCTAATGTGAAAAAAGAAGGTAATGACATTTCAATCATCACATACGGTGCAATGG
TTCAAGAATCAATGAAAGCTGCAGAAGAACTTGAAAAAGATGGTTATTCTGTTGAAGTAATTGACTTACGTACTGTTCAA
CCAATCGATGTTGACACAATTGTAGCTTCAGTTGAAAAAACTGGTCGTGCAGTTGTAGTTCAAGAAGCACAACGTCAAGC
TGGTGTTGGTGCAGCAGTTGTAGCTGAATTAAGTGAACGTGCAATCCTTTCATTAGAAGCACCTATTGGAAGAGTTGCAG
CAGCAGATACAATTTATCCATTCACTCAAGCTGAAAATGTTTGGTTACCAAACAAAAATGACATCATCGAAAAAGCAAAA
GAAACTTTAGAATTTTAA

Upstream 100 bases:

>100_bases
ACAAACTGTTACTTCTCTAATGGAAATTATGTATGAAGATATGCCTCAAAACTTAGCAGAACAATATGAAATTTACAAAG
AGAAGGAGTCGAAGTAAGCC

Downstream 100 bases:

>100_bases
TACATTTTAAAAGTTAACGAAGTTAGCGTATTTTAGTCTCATTGATTAAAATGAAATGTTTAATTTACGAAATCTTAGGA
GGGCAAAAACGTGGCATTTG

Product: transketolase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVME
VQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLIS
SIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQ
PIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAK
ETLEF

Sequences:

>Translated_325_residues
MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVME
VQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLIS
SIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQ
PIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAK
ETLEF
>Mature_324_residues
AQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEV
QFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISS
IRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQP
IDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAKE
TLEF

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=325, Percent_Identity=41.2307692307692, Blast_Score=257, Evalue=8e-69,
Organism=Homo sapiens, GI34101272, Length=325, Percent_Identity=41.2307692307692, Blast_Score=257, Evalue=8e-69,
Organism=Homo sapiens, GI156564403, Length=326, Percent_Identity=36.8098159509202, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI291084858, Length=326, Percent_Identity=35.2760736196319, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI225637461, Length=254, Percent_Identity=29.5275590551181, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI225637463, Length=254, Percent_Identity=29.5275590551181, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI225637459, Length=254, Percent_Identity=29.5275590551181, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI133778974, Length=97, Percent_Identity=39.1752577319588, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17506935, Length=325, Percent_Identity=39.0769230769231, Blast_Score=240, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17538422, Length=327, Percent_Identity=36.3914373088685, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6319698, Length=326, Percent_Identity=39.5705521472393, Blast_Score=225, Evalue=7e-60,
Organism=Drosophila melanogaster, GI160714828, Length=326, Percent_Identity=38.9570552147239, Blast_Score=247, Evalue=8e-66,
Organism=Drosophila melanogaster, GI160714832, Length=325, Percent_Identity=38.7692307692308, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI21358145, Length=326, Percent_Identity=38.0368098159509, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24650940, Length=326, Percent_Identity=38.0368098159509, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24650943, Length=90, Percent_Identity=43.3333333333333, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24650945, Length=90, Percent_Identity=43.3333333333333, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 35247; Mature: 35115

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAE
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCCCCCCCCHH
SGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFG
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCC
GGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLYRSF
CCCCCCCCCCCCCCHHEECCCCCEEEECCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHH
REEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQ
HHHCCCCCEEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
PIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYP
CCCHHHHHHHHHHCCCEEEEEHHHHHCCCCHHHHHHHHHHHEEEECCCCCHHHHHCCCCC
FTQAENVWLPNKNDIIEKAKETLEF
CCCCCCEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAE
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCCCCCCCCHH
SGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFG
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCC
GGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLYRSF
CCCCCCCCCCCCCCHHEECCCCCEEEECCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHH
REEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQ
HHHCCCCCEEEEECCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
PIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYP
CCCHHHHHHHHHHCCCEEEEEHHHHHCCCCHHHHHHHHHHHEEEECCCCCHHHHHCCCCC
FTQAENVWLPNKNDIIEKAKETLEF
CCCCCCEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA