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The map label for this gene is purL

Identifier: 148267562

GI number: 148267562

Start: 1169476

End: 1171665

Strand: Direct

Name: purL

Synonym: SaurJH9_1129

Alternate gene names: 148267562

Gene position: 1169476-1171665 (Clockwise)

Preceding gene: 148267561

Following gene: 148267563

Centisome position: 40.23

GC content: 34.93

Gene sequence:

>2190_bases
ATGTCTAAATTTATCGAACCAAGCGTTGAAGAAATTAAACTTGAAAAAGTATATCAAGATATGGGATTAAGTGATCAAGA
ATATGAAAAAGTTTGCGATATTTTAGGCAGACAACCTAACTTTACAGAAACAGGTATCTTTTCTGTTATGTGGAGTGAAC
ATTGCTCTTATAAACATTCTAAACCGTTTTTAAAGCAATTTCCTACGTCAGGTGAGCATGTGCTTATGGGTCCAGGTGAA
GGTGCAGGGGTAGTCGATATAGGTGATAATCAAGCCGTAGTATTTAAAGTAGAGTCTCACAATCATCCATCAGCAATTGA
ACCATATCAAGGGGCTGCTACAGGCGTTGGTGGAATCATTCGTGACATTGTTTCTATTGGGGCTAGACCTATTAATTTGT
TAAACAGTCTTAGATTTGGAGAATTAGATAATAAACAAAACCAAAGATTACTTAAAGGGGTTGTAAAGGGTATCGGAGGT
TATGGTAACTGCATTGGTATTCCAACAACTGCTGGTGAAATCGAATTTGATGAACGTTATGATGGCAATCCACTTGTTAA
TGCAATGTGTGTTGGTGTTATCAATCACGACATGATTCAAAAAGGCACAGCAAAAGGTGTAGGTAATTCGGTCATTTATG
TTGGTTTGAAAACTGGTCGAGATGGTATTCATGGTGCTACTTTTGCATCTGAAGAATTGACGGAAGAAAGCGAAAGTAAA
CGACCTTCTGTACAAATCGGTGATCCATTTGTAGGTAAAAAATTAATGGAAGCAACACTTGAAGCAATTACATTTGATGA
ATTAGTTGGTATTCAAGATATGGGTGCTGCTGGTTTAACATCTTCATCGTCTGAAATGGCGGCAAAAGGTGGTAGTGGGT
TACATTTGAGATTAGAACAAGTGCCAACACGTGAGCCAGGTATTTCTCCTTATGAAATGATGCTTTCAGAAACTCAAGAA
CGTATGTTACTAGTTGTTGAAAAAGGTAATGAACAAAAATTCTTAGATTTATTTGATAAGCACGAATTGGATAGTGCTGT
TATAGGTGAAGTTACAGATACAAATCGTTTTGTTTTAACATATGATGATGAAGTTTATGCTGACATTCCAGTTGAACCAC
TAGCTGATGAAGCACCTGTATATATTTTAGAAGGAGAAGAAAAAGATTATAATACTTCTAAAAATGATTATACACACATC
GATGTTAAAGATACTTTCTTTAAATTACTTAAGCATCCGACTATAGCATCTAAACACTATTTATATGATCAATACGACCA
ACAAGTTGGTGCCAATACGATAATTAAGCCAGGACTTCAAGCATCGGTAGTACGTGTGGAAGGCACAAATAAGGCAATTG
CTTCAACAATTGATGGTGAAGCGCGTTATGTATATAACAATCCATATGAAGGTGGAAAGATGGTAGTAGCTGAAGCTTAT
CGAAATTTAATTGCCGTGGGTGCAACACCATTAGCAATGACAGATTGTTTAAATTATGGTTCTCCTGAAAAGAAAGAAAT
CTATCAACAGTTGATAGATTCAACGAAAGGTATGGCAGAAGCATGCGACATTCTTAAGACACCAGTAGTTTCTGGAAATG
TATCTTTATATAACGAAACGAAAGGTACTTCTATTTTCCCAACACCAGTTGTTGGAATGGTAGGTTTGATTGAAAATGTA
AATTATTTAAATGATTTTGAACCTCAAGTTGGAGATAAATTATATTTAATCGGTGATACTAAGGACGACTTTGGTGGTAG
TCAACTTGAAAAGTTAATTTATGGCAAAGTTAATCATGAATTTGAGTCATTAGATTTGAGTTCAGAAGTTGAAAAAGGTG
AATCAATCAAGACCGCTATTCGTGAAGGACTATTATCACATGTTCAAACAGTTGGTAAAGGTGGCTTACTGATTACCTTA
GCTAAACTAAGTGCGCATTACGGTTTAGGATTAAAATCTTCAATAGATATAACAAATGCACAATTGTTTAGTGAGACACA
AGGCCGATATGTTGTTTCTGTTAAATCAGGTAAAACTTTAAATATTGATAATGCAATAGAAATTGGACTTTTAACAGATA
GTGATAATTTCAAAGTAACAACACCATATACAGAGATTAGTGAAAATGTTTCAGATATTAAACAAATATGGGAAGGGGCA
ATTGCTCAATGTTTAACTACTCAGGATTAA

Upstream 100 bases:

>100_bases
GGCATGATGCCACATCCTGAAAGAGCTTTAGAAACGTTGTTAGGTACTGATAGTGGTGTGAAATTATTTGAAGCGATGGT
AAAAAGTTGGAGGGAACAAC

Downstream 100 bases:

>100_bases
ACGAAGAATGTGGCGTGTTTGGTATTTGGAATCATCCTGAAGCAGCGCAACTAACATATATGGGACTTCATAGTTTGCAA
CATCGTGGTCAAGAAGGTGC

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGE
GAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGG
YGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESK
RPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQE
RMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHI
DVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAY
RNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENV
NYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITL
AKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGA
IAQCLTTQD

Sequences:

>Translated_729_residues
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGE
GAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGG
YGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESK
RPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQE
RMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHI
DVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAY
RNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENV
NYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITL
AKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGA
IAQCLTTQD
>Mature_728_residues
SKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEG
AGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGY
GNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKR
PSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQER
MLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHID
VKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYR
NLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVN
YLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLA
KLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAI
AQCLTTQD

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family

Homologues:

Organism=Escherichia coli, GI48994899, Length=826, Percent_Identity=23.2445520581114, Blast_Score=129, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321498, Length=570, Percent_Identity=24.0350877192982, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURL_STAA1 (A7X0W1)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441651.1
- ProteinModelPortal:   A7X0W1
- STRING:   A7X0W1
- EnsemblBacteria:   EBSTAT00000005168
- GeneID:   5559542
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1061
- eggNOG:   COG0046
- GeneTree:   EBGT00050000025071
- HOGENOM:   HBG311214
- OMA:   YGNSFGV
- ProtClustDB:   PRK01213
- BioCyc:   SAUR418127:SAHV_1061-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00420
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188
- TIGRFAMs:   TIGR01736

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =6.3.5.3

Molecular weight: Translated: 79564; Mature: 79433

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHS
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
KPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERY
HHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCC
DGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHC
RPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQ
CCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHCCCCCEEEEEEC
VPTREPGISPYEMMLSETQERMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLT
CCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCEEEEE
YDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHY
ECCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCC
LYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAY
HHHHHHHHCCCCCEECCCCCEEEEEEECCCCHHHHCCCCCEEEEECCCCCCCEEEHHHHH
RNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNET
HHHEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCEEEEECC
KGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHE
CCCEECCCHHHHHHHHHHCCCHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCC
FESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNA
HHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCCCCCHH
QLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGA
HHHHCCCCCEEEEECCCCEECCCCCEEEEEEECCCCEEEECCHHHHHCCHHHHHHHHHHH
IAQCLTTQD
HHHHHCCCC
>Mature Secondary Structure 
SKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHS
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
KPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERY
HHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCC
DGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHC
RPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQ
CCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHCCCCCEEEEEEC
VPTREPGISPYEMMLSETQERMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLT
CCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCEEEEE
YDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHY
ECCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCC
LYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAY
HHHHHHHHCCCCCEECCCCCEEEEEEECCCCHHHHCCCCCEEEEECCCCCCCEEEHHHHH
RNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNET
HHHEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCEEEEECC
KGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHE
CCCEECCCHHHHHHHHHHCCCHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCC
FESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNA
HHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCCCCCHH
QLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGA
HHHHCCCCCEEEEECCCCEECCCCCEEEEEEECCCCEEEECCHHHHHCCHHHHHHHHHHH
IAQCLTTQD
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA