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The map label for this gene is fabI [H]

Identifier: 148267443

GI number: 148267443

Start: 1063173

End: 1063943

Strand: Direct

Name: fabI [H]

Synonym: SaurJH9_1009

Alternate gene names: 148267443

Gene position: 1063173-1063943 (Clockwise)

Preceding gene: 148267442

Following gene: 148267445

Centisome position: 36.58

GC content: 35.41

Gene sequence:

>771_bases
ATGTTAAATCTTGAAAACAAAACATATGTCATCATGGGAATCGCTAATAAGCGTAGTATTGCTTTTGGTGTCGCTAAAGT
TTTAGATCAATTAGGTGCTAAATTAGTATTTACTTACCGTAAAGAACGTAGCCGTAAAGAGCTTGAAAAATTATTAGAAC
AATTAAATCAACCAGAAGCGCACTTATATCAAATTGATGTTCAAAGCGATGAAGAGGTTATTAATGGTTTTGAGCAAATT
GGTAAAGATGTTGGCAATATTGATGGTGTATATCATTCAATCGCATTTGCTAATATGGAAGACTTACGCGGACGCTTTTC
TGAAACTTCACGTGAAGGCTTCTTGTTAGCTCAAGACATTAGTTCTTACTCATTAACAATTGTGGCTCATGAAGCTAAAA
AATTAATGCCAGAAGGTGGTAGCATTGTTGCAACAACATATTTAGGTGGCGAATTCGCAGTTCAAAATTATAATGTGATG
GGTGTTGCTAAAGCGAGCTTAGAAGCAAATGTTAAATATTTAGCATTAGACTTAGGTCCTGATAATATTCGCGTTAATGC
AATTTCAGCTGGTCCAATCCGTACATTAAGTGCAAAAGGTGTGGGTGGTTTCAATACAATTCTTAAAGAAATCGAAGAGC
GTGCACCTTTAAAACGTAACGTTGATCAAGTAGAAGTAGGTAAAACAGCGGCTTACTTATTAAGTGACTTATCAAGTGGC
GTTACAGGTGAAAATATTCATGTAGATAGCGGATTCCACGCAATTAAATAA

Upstream 100 bases:

>100_bases
GTCATAATAGTGTTAAAATGTATTGACGAATAAAAAGTTAGTTAAAACTGGGATTAGATATTCTATCCGTTAAATTAATT
ATTATAAGGAGTTATCTTAC

Downstream 100 bases:

>100_bases
TATCATTCAACAGCTTTGTTCACGTTATCATATATGTGAGCAAAGCTTTTTTGCTTTTATAATAATCGGACTGATGGAAA
ATTATTTGATATTTCATCTG

Product: enoyl-(acyl carrier protein) reductase

Products: NA

Alternate protein names: Cold shock-induced protein 15; CSI15; NADH-dependent enoyl-ACP reductase; Vegetative protein 241; VEG241 [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQI
GKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVM
GVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSG
VTGENIHVDSGFHAIK

Sequences:

>Translated_256_residues
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQI
GKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVM
GVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSG
VTGENIHVDSGFHAIK
>Mature_256_residues
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQI
GKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVM
GVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSG
VTGENIHVDSGFHAIK

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=26.1410788381743, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787545, Length=250, Percent_Identity=44, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=26.7924528301887, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 27992; Mature: 27992

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCCCE
HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI
EEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECC
SSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGP
CCEEEEEEEECHHHHCCCCCCEEEEEEECCEEEEECCCEEEEEECCHHCCEEEEEEEECC
DNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSG
CCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCC
VTGENIHVDSGFHAIK
CCCCEEEECCCCCCCC
>Mature Secondary Structure
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCCCE
HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI
EEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECC
SSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGP
CCEEEEEEEECHHHHCCCCCCEEEEEEECCEEEEECCCEEEEEECCHHCCEEEEEEEECC
DNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSG
CCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCC
VTGENIHVDSGFHAIK
CCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 8755892; 9298659 [H]