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The map label for this gene is pgi

Identifier: 148267396

GI number: 148267396

Start: 1008005

End: 1009336

Strand: Direct

Name: pgi

Synonym: SaurJH9_0962

Alternate gene names: 148267396

Gene position: 1008005-1009336 (Clockwise)

Preceding gene: 148267392

Following gene: 148267397

Centisome position: 34.68

GC content: 33.56

Gene sequence:

>1332_bases
ATGACTCATATTCAATTAGATTTTAGTAAAACGTTAGAATTTTTCGGTGAACACGAATTAAAACAACAACAAGAAATTGT
TAAATCAATTCACAAAACAATTCATGAAGGTACTGGTGCAGGTAGTGACTTCTTAGGCTGGGTTGATTTACCAGTTGATT
ACGACAAAGAAGAATTTTCAAGAATTGTTGAAGCATCAAAACGCATTAAAGAAAATTCTGATGTTTTAGTAGTCATCGGT
ATTGGTGGTTCTTACTTAGGTGCACGTGCAGCAATCGAAATGTTAACGTCATCATTTAGAAACAGCAATGAATACCCTGA
AATTGTATTTGTTGGTAATCACTTATCATCAACATATACGAAAGAGTTAGTTGATTATTTAGCAGACAAAGATTTCTCTG
TAAACGTTATTTCTAAATCTGGTACAACTACAGAACCAGCAGTTGCATTTAGATTGTTCAAACAATTAGTTGAAGAAAGA
TACGGTAAAGAAGAAGCACAAAAACGTATATTTGCAACAACGGATAAAGAAAAAGGTGCTTTAAAACAGTTGGCTACAAA
CGAAGGTTATGAAACGTTTATCGTACCTGATGATGTAGGTGGAAGATATTCTGTTTTAACAGCAGTAGGATTATTACCAA
TTGCAACAGCTGGAATTAACATCGAAGCTATGATGATTGGTGCTGCAAAAGCACGTGAAGAATTATCTTCAGATAAATTA
GAAGACAACATTGCATACCAATATGCGACAATTCGAAACATTTTATATGCAAAAGGTTATACAACAGAAATGTTGATTAA
CTATGAACCATCTATGCAATACTTTAATGAATGGTGGAAACAATTATTTGGTGAATCAGAAGGTAAAGACTTCAAAGGTA
TCTATCCTTCAAGTGCCAACTACACAACTGATTTACATTCTTTAGGTCAATATGTACAAGAAGGCCGTCGTTTCTTATTC
GAAACAGTGGTAAAAGTAAATCATCCTAAATATGATATTACTATTGAAAAAGATAGTGATGATCTAGACGGATTAAATTA
TTTGGCTGGTAAAACAATCGACGAAGTTAACACAAAAGCATTCGAAGGTACATTATTAGCGCATACTGATGGTGGTGTTC
CTAACATGGTAGTGAACATTCCACAATTAGATGAAGAAACTTTCGGTTATGTCGTATACTTCTTCGAACTTGCTTGTGCA
ATGAGTGGATACCAATTAGGTGTAAATCCATTTAACCAACCTGGTGTAGAAGCATATAAACAAAACATGTTCGCATTATT
AGGTAAACCTGGTTTTGAAGACTTGAAAAAAGAATTAGAAGAGCGTTTATAA

Upstream 100 bases:

>100_bases
TAAATATCAATTTTATTGATTAAGTACAAACTTGTGAATTGAATCGCAAACGTAAACTTAGTAAAATTAAGATATTAAAT
GAAACAGGAGGCTTTTATAG

Downstream 100 bases:

>100_bases
AATACATTACTTCAATGATTAGTGAAGTTTGAAAAGATAGAACTAGACGTTAACTATTTAAAGCATATTTTCGAGGTTGT
CATTACAAATGTAAAAATGT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIG
IGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEER
YGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKL
EDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLF
ETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACA
MSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL

Sequences:

>Translated_443_residues
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIG
IGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEER
YGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKL
EDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLF
ETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACA
MSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>Mature_442_residues
THIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGI
GGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERY
GKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLE
DNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFE
TVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAM
SGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Caenorhabditis elegans, GI71996708, Length=419, Percent_Identity=26.0143198090692, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996703, Length=419, Percent_Identity=26.0143198090692, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319673, Length=375, Percent_Identity=24.2666666666667, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_STAA1 (A7X0H6)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441547.1
- ProteinModelPortal:   A7X0H6
- SMR:   A7X0H6
- STRING:   A7X0H6
- EnsemblBacteria:   EBSTAT00000005214
- GeneID:   5561694
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0957
- eggNOG:   COG0166
- GeneTree:   EBGT00050000024507
- HOGENOM:   HBG615843
- OMA:   YVNDRAY
- ProtClustDB:   PRK14097
- BioCyc:   SAUR418127:SAHV_0957-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 49795; Mature: 49663

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 285-285 ACT_SITE 306-306 ACT_SITE 420-420

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFS
CCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHH
RIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYT
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHH
KELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGA
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHEEECCCCHHHH
LKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKL
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHH
EDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSAN
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
YTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCCCHHHHCCHH
FEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYK
HCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHH
QNMFALLGKPGFEDLKKELEERL
HHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
THIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFS
CEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHH
RIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYT
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHH
KELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGA
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHEEECCCCHHHH
LKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKL
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHH
EDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSAN
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
YTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCCCHHHHCCHH
FEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYK
HCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHH
QNMFALLGKPGFEDLKKELEERL
HHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA