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The map label for this gene is gluD [H]

Identifier: 148267392

GI number: 148267392

Start: 1002095

End: 1003381

Strand: Direct

Name: gluD [H]

Synonym: SaurJH9_0958

Alternate gene names: 148267392

Gene position: 1002095-1003381 (Clockwise)

Preceding gene: 148267391

Following gene: 148267396

Centisome position: 34.48

GC content: 36.91

Gene sequence:

>1287_bases
TTGAAAGCGAAATCATTAGGTAAAGAAGAGGCGAAAAGGATCATGACTGAGAACAATAATTTAGTAACTTCTACTCAAGG
AATTATTAAAGAAGCATTGCATAAATTGGGATTTGACGAAGGAATGTACGATTTAATTAAAGAACCTTTAAGAATGTTAC
AAGTGCGTATCCCTGTACGAATGGATGATGGCACAGTTAAAACATTCACAGGTTACCGTGCGCAACATAATGATGCTGTT
GGACCAACAAAAGGGGGCGTGCGTTTCCACCCAGATGTTGATGAAGAAGAAGTAAAAGCATTATCAATGTGGATGACTTT
GAAATGTGGCATTGTAAACTTACCATACGGTGGTGGTAAGGGTGGTATCGTTTGTGATCCACGTCAAATGAGCATTCATG
AAGTTGAACGTTTATCACGCGGATATGTAAGAGCAATTTCACAATTCGTAGGTCCGAACAAAGATATTCCAGCACCAGAT
GTATTTACAAACTCACAAATTATGGCTTGGATGATGGATGAATATAGTGCATTAGATAAATTTAATTCACCAGGTTTCAT
CACAGGTAAACCAATTGTATTGGGTGGTTCTCATGGACGCGACAGATCAACTGCACTAGGTGTAGTTATTGCAATTGAAC
AAGCTGCAAAACGTCGTAATATGCAAATTGAAGGTGCCAAGGTTGTTATTCAAGGTTTCGGTAATGCCGGAAGTTTCTTA
GCTAAATTCTTATATGATTTAGGTGCAAAAATTGTAGGTATCTCTGATGCTTACGGTGCATTACACGATCCAAATGGCTT
AGATATAGATTATTTATTAGACCGTCGTGATAGTTTTGGTACGGTAACAAATTTATTTGAAGAAACAATCTCAAATAAAG
AATTGTTTGAATTAGATTGTGACATTTTAGTACCAGCGGCTATTTCAAACCAAATTACAGAAGACAATGCACATGATATT
AAAGCTAGTATCGTTGTTGAAGCTGCTAATGGACCTACAACACCAGAAGCAACACGTATTTTAACTGAACGTGGTATATT
ATTAGTTCCAGACGTATTAGCAAGTGCTGGTGGTGTAACGGTTTCTTACTTCGAATGGGTACAAAATAATCAAGGTTATT
ATTGGTCTGAAGAAGAAGTAAATGAAAAGCTACGTGAAAAATTAGAAGCGGCATTTGACACGATTTACGAATTGTCTCAA
AATCGAAAAATAGATATGAGACTTGCAGCATATATCATAGGTATTAAACGTACAGCAGAAGCAGCTAGATATCGTGGTTG
GGCATAA

Upstream 100 bases:

>100_bases
TGCACTTGAAAAAATAAGACATGTATTTCAATAATGTCAAAAAGTTGTAACAATCAGTTTGTAAGGGCTTTAAAAAGGAA
TACGTTATGTTACAATATGT

Downstream 100 bases:

>100_bases
TTAATTATCATATGTGATTTAACGAGCTTGGGACAGAAAACAAAGCCCTAAGCTCGTTAATTTTATTTTAGCAGCAGTTG
ACTGTAAAACAATGCCCGTG

Product: Glu/Leu/Phe/Val dehydrogenase, C terminal

Products: NA

Alternate protein names: NAD-GDH [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKAKSLGKEEAKRIMTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAV
GPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPD
VFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFL
AKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDI
KASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQ
NRKIDMRLAAYIIGIKRTAEAARYRGWA

Sequences:

>Translated_428_residues
MKAKSLGKEEAKRIMTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAV
GPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPD
VFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFL
AKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDI
KASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQ
NRKIDMRLAAYIIGIKRTAEAARYRGWA
>Mature_428_residues
MKAKSLGKEEAKRIMTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAV
GPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPD
VFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFL
AKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDI
KASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQ
NRKIDMRLAAYIIGIKRTAEAARYRGWA

Specific function: Unknown

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

Organism=Homo sapiens, GI31377775, Length=342, Percent_Identity=39.766081871345, Blast_Score=271, Evalue=9e-73,
Organism=Homo sapiens, GI4885281, Length=342, Percent_Identity=39.4736842105263, Blast_Score=268, Evalue=6e-72,
Organism=Escherichia coli, GI1788059, Length=402, Percent_Identity=30.8457711442786, Blast_Score=179, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17544676, Length=346, Percent_Identity=40.7514450867052, Blast_Score=262, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6319256, Length=386, Percent_Identity=29.5336787564767, Blast_Score=149, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6324951, Length=399, Percent_Identity=27.5689223057644, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45553475, Length=382, Percent_Identity=39.0052356020942, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI45549226, Length=346, Percent_Identity=40.1734104046243, Blast_Score=268, Evalue=7e-72,
Organism=Drosophila melanogaster, GI24649283, Length=330, Percent_Identity=40.9090909090909, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24649460, Length=281, Percent_Identity=39.5017793594306, Blast_Score=212, Evalue=4e-55,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 9362 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR014362
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.2 [H]

Molecular weight: Translated: 47332; Mature: 47332

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00074 GLFV_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKSLGKEEAKRIMTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVR
CCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECCEE
MDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGK
ECCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHEEECCEEECCCCCCC
GGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDK
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
FNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFL
CCCCCEECCCCEEEECCCCCCCHHHEEEEEEEHHHHHHCCCEECCCEEEEEECCCHHHHH
AKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDC
HHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECC
DILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVT
CEEECHHHCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCEEECHHHHCCCCCE
VSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAE
EHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHH
AARYRGWA
HHHCCCCC
>Mature Secondary Structure
MKAKSLGKEEAKRIMTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVR
CCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECCEE
MDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGK
ECCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHEEECCEEECCCCCCC
GGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDK
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
FNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFL
CCCCCEECCCCEEEECCCCCCCHHHEEEEEEEHHHHHHCCCEECCCEEEEEECCCHHHHH
AKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDC
HHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECC
DILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVT
CEEECHHHCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCEEECHHHHCCCCCE
VSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAE
EHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHH
AARYRGWA
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA