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The map label for this gene is rocD [H]

Identifier: 148267391

GI number: 148267391

Start: 1000838

End: 1002028

Strand: Direct

Name: rocD [H]

Synonym: SaurJH9_0957

Alternate gene names: 148267391

Gene position: 1000838-1002028 (Clockwise)

Preceding gene: 148267390

Following gene: 148267392

Centisome position: 34.43

GC content: 35.77

Gene sequence:

>1191_bases
ATGACTAAATCTGAAAAAATTATTGAGTTAACAAATCATTACGGAGCACATAATTATTTACCATTGCCAATTGTCATTTC
AGAAGCTGAAGGGGTATGGGTTAAAGATCCTGAAGGCAATAAATATATGGATATGTTATCTGCATATTCCGCTGTTAACC
AAGGTCATAGACATCCGAAAATTATTCAAGCATTAAAAGATCAAGCTGATAAAGTGACTCTAGTTTCACGTGCTTTTCAT
AGTGATAACTTAGGTGAATGGTACGAAAAAATTTGTAAACTGGCAGGTAAAGATAAAGCTTTACCAATGAATACAGGTGC
TGAAGCAGTAGAAACAGCTTTGAAAGCAGCACGACGCTGGGCATACGATGTTAAAGGAATTGAGCCAAATAAAGCAGAAA
TCATTGCATTTAATGGTAACTTCCATGGTCGAACAATGGCGCCAGTTTCATTATCTTCAGAAGCAGAATACCAACGTGGT
TATGGTCCGTTATTAGATGGATTTAGAAAAGTTGATTTTGGAGATGTAGATGCATTGGAAGCTGCAATTAATGAAAATAC
TGCAGCAGTTTTAGTAGAACCAATTCAAGGTGAAGCGGGTATAAATATACCGCCAGAAGGATATTTGAAAGCAATTAGAG
AATTATGTGATGAACATAATGTCTTATTTATTGCTGACGAAATCCAAGCAGGATTAGGTCGTTCGGGTAAATTATTTGCT
ACGGATTGGGATAATGTAAAACCTGATGTCTATATTTTAGGTAAAGCACTAGGTGGTGGTGTCTTCCCAATTTCTGTTGT
ATTAGCAGATAAAGAAGTATTAGATGTCTTTACACCTGGCTCACATGGTTCAACATTTGGTGGTAATCCACTTGCTTGTG
CTGCATCAATTGCTGCATTAGATGTTATCGTTGATGAGGATTTACCAGGGCGCTCTTTAGAATTAGGAGATTATTTTAAA
GAACAATTAAAGCAAATTGATCATCCATCAATTAAAGAAGTCCGTGGACGTGGTTTGTTTATAGGTGTGGAACTTAATGA
AAGTGCTAGACCATATTGTGAAGCTTTGAAAGAAGAAGGCTTATTATGTAAAGAAACGCATGATACTGTCATTCGTTTTG
CACCACCATTAATTATTACTAAAGAAGAATTGGACCTTGCACTTGAAAAAATAAGACATGTATTTCAATAA

Upstream 100 bases:

>100_bases
CATCTTTTTTGGTGGAAAAGTATCTGCTTTGAAAACTAATGTAATTATTTGGATAATGTTTCATGTATAATAGTTATAAA
TGATGAAAAGGGGAGATATG

Downstream 100 bases:

>100_bases
TGTCAAAAAGTTGTAACAATCAGTTTGTAAGGGCTTTAAAAAGGAATACGTTATGTTACAATATGTTTGAAAGCGAAATC
ATTAGGTAAAGAAGAGGCGA

Product: ornithine--oxo-acid transaminase

Products: NA

Alternate protein names: OAT 2; Ornithine--oxo-acid aminotransferase 2 [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFH
SDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
YGPLLDGFRKVDFGDVDALEAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFK
EQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ

Sequences:

>Translated_396_residues
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFH
SDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
YGPLLDGFRKVDFGDVDALEAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFK
EQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>Mature_395_residues
TKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHS
DNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGY
GPLLDGFRKVDFGDVDALEAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFAT
DWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKE
QLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=393, Percent_Identity=49.618320610687, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=46.9798657718121, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI13994255, Length=431, Percent_Identity=29.4663573085847, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=28.0952380952381, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=28.0927835051546, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=27.3809523809524, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI24119277, Length=411, Percent_Identity=26.7639902676399, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI145693181, Length=374, Percent_Identity=37.1657754010695, Blast_Score=257, Evalue=8e-70,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=36.8146214099217, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1788044, Length=379, Percent_Identity=36.1477572559367, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=34.75, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=33.0097087378641, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786991, Length=408, Percent_Identity=29.656862745098, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786349, Length=298, Percent_Identity=27.8523489932886, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=49.8721227621483, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=47.037037037037, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71981843, Length=173, Percent_Identity=47.9768786127168, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=31.4814814814815, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=425, Percent_Identity=28.7058823529412, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=416, Percent_Identity=25.9615384615385, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=49.2682926829268, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6324432, Length=372, Percent_Identity=33.0645161290323, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=406, Percent_Identity=25.615763546798, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=371, Percent_Identity=27.4932614555256, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=49.492385786802, Blast_Score=403, Evalue=1e-112,
Organism=Drosophila melanogaster, GI161085790, Length=431, Percent_Identity=29.6983758700696, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28574759, Length=424, Percent_Identity=29.7169811320755, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI21356575, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281366494, Length=421, Percent_Identity=25.1781472684086, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667139, Length=421, Percent_Identity=25.1781472684086, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667143, Length=421, Percent_Identity=25.1781472684086, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 43419; Mature: 43288

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPK
CCCCCHHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRW
HHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALE
HHHCCCCCCCCEEEEEECCCCCCCEECCEECCCCCHHHCCCCHHHHHHHCCCCCCHHHHH
AAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAAL
ECCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCHHHHHHHHHHE
DVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
CEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPK
CCCCHHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRW
HHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALE
HHHCCCCCCCCEEEEEECCCCCCCEECCEECCCCCHHHCCCCHHHHHHHCCCCCCHHHHH
AAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAAL
ECCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCHHHHHHHHHHE
DVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
CEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA