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The map label for this gene is pgk

Identifier: 148267233

GI number: 148267233

Start: 875658

End: 876848

Strand: Direct

Name: pgk

Synonym: SaurJH9_0798

Alternate gene names: 148267233

Gene position: 875658-876848 (Clockwise)

Preceding gene: 148267232

Following gene: 148267234

Centisome position: 30.13

GC content: 34.68

Gene sequence:

>1191_bases
ATGGCTAAAAAAATTGTTTCTGATTTAGATCTTAAAGGTAAAACAGTCCTAGTACGTGCTGATTTTAACGTACCTTTAAA
AGACGGTGAAATTACTAATGACAACCGTATCGTTCAAGCTTTACCTACAATTCAATACATCATCGAACAAGGTGGTAAAA
TCGTACTATTTTCACATTTAGGTAAAGTGAAAGAAGAAAGTGATAAAGCAAAATTAACTTTACGTCCAGTTGCTGAAGAC
TTATCTAAGAAATTAGATAAAGAAGTTGTTTTCGTACCAGAAACACGCGGCGAAAAACTTGAAGCTGCTATTAAAGACCT
TAAAGAAGGCGACGTATTATTAGTTGAAAATACACGTTATGAAGATTTAGACGGTAAAAAAGAATCTAAAAATGATCCAG
AATTAGGTAAATACTGGGCATCTTTAGGTGATGTGTTTGTAAATGATGCTTTTGGTACTGCGCATCGTGAGCATGCATCT
AATGTTGGTATTTCTACACATTTAGAAACTGCAGCTGGATTCTTAATGGATAAAGAAATTAAGTTTATTGGTGGCGTAGT
TAACGATCCACATAAACCAGTTGTTGCTATTTTAGGTGGAGCAAAAGTATCTGACAAAATTAATGTCATCAAAAACTTAG
TTAACATAGCTGATAAAATTATCATCGGCGGAGGTATGGCTTATACTTTCTTAAAAGCGCAAGGTAAAGAAATTGGTATT
TCATTATTAGAAGAAGATAAAATCGACTTCGCAAAAGATTTATTAGAAAAACATGGTGATAAAATTGTATTACCAGTAGA
CACTAAAGTTGCTAAAGAATTTTCTAATGATGCCAAAATCACTGTAGTACCATCTGATTCAATTCCAGCAGACCAAGAAG
GTATGGATATTGGACCAAACACTGTAAAATTATTTGCAGATGAATTAGAAGGTGCGCACACTGTTGTATGGAATGGACCT
ATGGGTGTATTCGAGTTCAGTAACTTTGCACAAGGTACAATTGGTGTATGTAAAGCAATTGCAAACCTTAAAGATGCAAT
TACGATTATCGGTGGCGGTGATTCAGCTGCAGCAGCAATCTCTTTAGGTTTTGAAAATGACTTCACTCATATTTCAACTG
GTGGCGGCGCGTCATTAGAGTACCTAGAAGGTAAAGAATTGCCTGGTATCAAAGCAATCAATAATAAATAA

Upstream 100 bases:

>100_bases
AACTATTTAGCATTAATTAAAGCTTATGAGTAAGCGGGGAGCACAAACGCTTCTCCGCTTATTTTTATATAAAATTTCCT
AATTACAAGGAGGAAACACC

Downstream 100 bases:

>100_bases
TAAAGTGATAGTTTAAAGTGATGTGGCATGTTTGTTTAACATTGTTACGGGAAAACAGTCACAAGATGACATCGTGTTTC
ATCACTTTTCAAAAATATTT

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAED
LSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHAS
NVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGI
SLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGP
MGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK

Sequences:

>Translated_396_residues
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAED
LSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHAS
NVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGI
SLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGP
MGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>Mature_395_residues
AKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDL
SKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASN
VGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGIS
LLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPM
GVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI4505763, Length=406, Percent_Identity=44.0886699507389, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI31543397, Length=415, Percent_Identity=42.6506024096386, Blast_Score=309, Evalue=2e-84,
Organism=Escherichia coli, GI1789294, Length=392, Percent_Identity=43.8775510204082, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17508823, Length=413, Percent_Identity=47.2154963680387, Blast_Score=345, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6319857, Length=413, Percent_Identity=46.0048426150121, Blast_Score=325, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24581203, Length=410, Percent_Identity=43.1707317073171, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI17136394, Length=409, Percent_Identity=43.520782396088, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_STAA1 (A7WZS6)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441360.1
- ProteinModelPortal:   A7WZS6
- STRING:   A7WZS6
- EnsemblBacteria:   EBSTAT00000004778
- GeneID:   5559411
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0770
- eggNOG:   COG0126
- GeneTree:   EBGT00050000025307
- HOGENOM:   HBG453500
- OMA:   NCAIILP
- ProtClustDB:   PRK00073
- BioCyc:   SAUR418127:SAHV_0770-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 42602; Mature: 42471

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 36-36 BINDING 119-119 BINDING 156-156 BINDING 206-206 BINDING 294-294 BINDING 325-325

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHL
CCCHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEEECC
GKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRY
CCHHCCCCCCEEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCC
EDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEI
CCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHCCCCCEEHHHHHHHHHHCCCH
KFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGI
HEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCEECE
SLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPN
EEECCCCHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
TVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAI
HHEEEHHHCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEE
SLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
EECCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
AKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHL
CCHHHHHCCCCCCEEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEEECC
GKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRY
CCHHCCCCCCEEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCC
EDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEI
CCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHCCCCCEEHHHHHHHHHHCCCH
KFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGI
HEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCEECE
SLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPN
EEECCCCHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
TVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAI
HHEEEHHHCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEE
SLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
EECCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA