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The map label for this gene is gapA1

Identifier: 148267232

GI number: 148267232

Start: 874509

End: 875519

Strand: Direct

Name: gapA1

Synonym: SaurJH9_0797

Alternate gene names: 148267232

Gene position: 874509-875519 (Clockwise)

Preceding gene: 148267231

Following gene: 148267233

Centisome position: 30.09

GC content: 37.98

Gene sequence:

>1011_bases
ATGGCAGTAAAAGTAGCAATTAATGGTTTTGGTAGAATTGGTCGTTTAGCATTCAGAAGAATTCAAGAAGTAGAAGGTCT
TGAAGTTGTAGCAGTAAACGACTTAACAGATGACGACATGTTAGCGCATTTATTAAAATATGACACTATGCAAGGTCGTT
TCACAGGTGAAGTAGAGGTAGTTGATGGTGGTTTCCGCGTAAATGGTAAAGAAGTTAAATCATTCAGTGAACCAGATGCA
AGCAAATTACCTTGGAAAGACTTAAATATCGATGTAGTGTTAGAATGTACTGGTTTCTACACTGATAAAGATAAAGCACA
AGCTCATATTGAAGCAGGCGCTAAAAAAGTATTAATCTCAGCACCAGCTACTGGTGACTTAAAAACAATCGTATTCAACA
CTAACCACCAAGAGTTAGACGGTTCTGAAACAGTTGTTTCAGGTGCTTCATGTACTACAAACTCATTAGCACCAGTTGCT
AAAGTTTTAAACGATGACTTTGGTTTAGTTGAAGGTTTAATGACTACAATTCACGCTTACACAGGTGATCAAAATACACA
AGACGCACCTCACAGAAAAGGTGACAAACGTCGTGCTCGTGCAGCGGCAGAAAACATCATCCCTAACTCAACAGGTGCTG
CTAAAGCTATCGGTAAAGTTATTCCTGAAATCGATGGTAAATTAGATGGTGGTGCACAACGTGTTCCTGTAGCTACAGGT
TCATTAACTGAATTAACAGTAGTATTAGAAAAACAAGACGTAACAGTTGAACAAGTTAACGAAGCTATGAAAAATGCTTC
AAACGAATCATTCGGTTACACTGAAGACGAAATCGTTTCTTCAGACGTTGTAGGTATGACTTACGGTTCATTATTCGACG
CTACACAAACTCGTGTAATGTCAGTTGGCGACCGTCAATTAGTTAAAGTTGCAGCTTGGTATGATAACGAAATGTCATAT
ACTGCACAATTAGTTCGTACATTAGCATACTTAGCTGAACTTTCTAAATAA

Upstream 100 bases:

>100_bases
ACAGTGTTAATCACTGATGAAGCCGCAGCAAAGATAATACTTGAATAAGAGATAAAAAGTTTAATACTTTTTAAATATCA
TTTTAAAGGAGGCCATTATA

Downstream 100 bases:

>100_bases
TTTTAGTATAGTTTTTATTCAAATACGCTAGTGCTCAGAACTATTTAGCATTAATTAAAGCTTATGAGTAAGCGGGGAGC
ACAAACGCTTCTCCGCTTAT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH 1

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDA
SKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVA
KVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATG
SLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSY
TAQLVRTLAYLAELSK

Sequences:

>Translated_336_residues
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDA
SKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVA
KVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATG
SLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSY
TAQLVRTLAYLAELSK
>Mature_335_residues
AVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDAS
KLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAK
VLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGS
LTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYT
AQLVRTLAYLAELSK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=44.6428571428571, Blast_Score=277, Evalue=8e-75,
Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=44.7447447447448, Blast_Score=267, Evalue=1e-71,
Organism=Escherichia coli, GI1788079, Length=337, Percent_Identity=47.1810089020772, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI1789295, Length=343, Percent_Identity=39.3586005830904, Blast_Score=234, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=45.8823529411765, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=45.2941176470588, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17568413, Length=340, Percent_Identity=43.8235294117647, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI32566163, Length=340, Percent_Identity=43.8235294117647, Blast_Score=264, Evalue=6e-71,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=46.7261904761905, Blast_Score=295, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=45.8333333333333, Blast_Score=285, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=45.2380952380952, Blast_Score=283, Evalue=2e-77,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=45.7831325301205, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=45.7831325301205, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=45.4819277108434, Blast_Score=264, Evalue=6e-71,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=45.4819277108434, Blast_Score=264, Evalue=6e-71,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=41.3897280966767, Blast_Score=256, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G3P1_STAAC (Q5HHP5)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185712.1
- ProteinModelPortal:   Q5HHP5
- SMR:   Q5HHP5
- STRING:   Q5HHP5
- EnsemblBacteria:   EBSTAT00000009483
- GeneID:   3238183
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL0838
- TIGR:   SACOL0838
- eggNOG:   COG0057
- GeneTree:   EBGT00050000024492
- HOGENOM:   HBG571736
- OMA:   MKAAANE
- ProtClustDB:   CLSK884889
- BioCyc:   SAUR93062:SACOL0838-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR10836
- PIRSF:   PIRSF000149
- PRINTS:   PR00078
- SMART:   SM00846
- TIGRFAMs:   TIGR01534

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N

EC number: =1.2.1.12

Molecular weight: Translated: 36281; Mature: 36150

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00071 GAPDH; PS00211 ABC_TRANSPORTER_1

Important sites: ACT_SITE 151-151 BINDING 34-34 BINDING 181-181 BINDING 198-198 BINDING 234-234 BINDING 316-316

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEV
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCEECCEEEE
VDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLIS
EECCEEECHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEE
APATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAY
CCCCCCEEEEEECCCCCCCCCCHHEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
TGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATG
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
SLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVM
CCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
SVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
HCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEV
EEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCEECCEEEE
VDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLIS
EECCEEECHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEE
APATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAY
CCCCCCEEEEEECCCCCCCCCCHHEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
TGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATG
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
SLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVM
CCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
SVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
HCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA