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The map label for this gene is hprK

Identifier: 148267220

GI number: 148267220

Start: 860495

End: 861427

Strand: Direct

Name: hprK

Synonym: SaurJH9_0784

Alternate gene names: 148267220

Gene position: 860495-861427 (Clockwise)

Preceding gene: 148267219

Following gene: 148267221

Centisome position: 29.6

GC content: 35.37

Gene sequence:

>933_bases
ATGTTAACGACAGAAAAACTAGTTGAAACATTAAAGTTAGATTTAATCGCTGGTGAAGAAGGACTATCGAAGCCAATTAA
AAATGCTGATATATCAAGACCAGGCTTAGAGATGGCAGGTTATTTTTCACATTATGCGTCAGATAGAATACAACTATTAG
GAACAACGGAACTATCGTTTTACAATTTATTACCAGATAAGGATCGCGCAGGTCGTATGCGTAAACTATGCAGACCAGAA
ACGCCTGCAATTATTGTGACACGTGGATTGCAGCCACCAGAAGAATTAGTTGAAGCTGCAAAAGAATTAAATACCCCACT
TATAGTTGCTAAAGATGCGACTACAAGTTTAATGAGTCGCTTAACAACGTTTTTAGAGCATGCACTTGCAAAGACGACAT
CTTTACATGGTGTTTTAGTAGATGTTTACGGTGTTGGTGTACTAATTACCGGTGATTCAGGAATAGGTAAAAGTGAGACT
GCGTTGGAATTAGTTAAACGTGGGCATAGATTAGTAGCAGATGATAATGTAGAAATACGTCAAATTAATAAAGATGAACT
AATAGGGAAACCACCAAAGTTAATAGAACATCTATTAGAAATACGTGGACTAGGTATTATCAATGTTATGACTTTATTTG
GCGCGGGTTCAATATTAACTGAAAAACGAATTAGATTAAATATTAATTTGGAAAACTGGAACAAGCAAAAGTTATATGAC
CGCGTAGGTCTTAATGAAGAGACGCTAAGTATTTTAGATACTGAAATCACTAAAAAAACAATACCTGTAAGACCTGGTAG
AAATGTTGCGGTAATTATTGAGGTCGCTGCAATGAACTATCGATTAAATATCATGGGCATTAACACTGCCGAAGAATTTA
GTGAAAGATTAAATGAAGAAATTATCAAGAACAGTCATAAGAGTGAGGAGTAG

Upstream 100 bases:

>100_bases
ATTAATATTTATTTTAGCTTTTCAATGTAGATTGGTGTTATATTTTTGATATGATAAGAAGAGATGTAAGAGTAGGGATA
AATACAATTGAGGTGAACCC

Downstream 100 bases:

>100_bases
GTTGAATGGGTATTGTATTTAACTATATAGATCCTGTGGCATTTAACTTAGGACCACTGAGTGTACGATGGTATGGAATT
ATCATTGCTGTCGGAATATT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPE
TPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSET
ALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYD
RVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE

Sequences:

>Translated_310_residues
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPE
TPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSET
ALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYD
RVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>Mature_310_residues
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPE
TPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSET
ALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYD
RVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_STAA1 (A7WZQ8)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441347.1
- ProteinModelPortal:   A7WZQ8
- SMR:   A7WZQ8
- STRING:   A7WZQ8
- EnsemblBacteria:   EBSTAT00000003428
- GeneID:   5561264
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0757
- eggNOG:   COG1493
- GeneTree:   EBGT00050000025026
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   SAUR418127:SAHV_0757-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34482; Mature: 34482

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: ACT_SITE 136-136 ACT_SITE 157-157 ACT_SITE 175-175 ACT_SITE 241-241

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSF
CCCHHHHHHHHHHHEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCE
YNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSR
EECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHH
LTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIR
HHHHHHHHHHHHHHHCEEEEEEECCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCEEE
QINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYD
ECCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEECCEEEEEEEECCCCHHHHHH
RVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEE
HHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCEEEEEEECCCHHHHHHHHHHH
IIKNSHKSEE
HHHCCCCCCC
>Mature Secondary Structure
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSF
CCCHHHHHHHHHHHEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCE
YNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSR
EECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHH
LTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIR
HHHHHHHHHHHHHHHCEEEEEEECCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCEEE
QINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYD
ECCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEECCEEEEEEEECCCCHHHHHH
RVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEE
HHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCEEEEEEECCCHHHHHHHHHHH
IIKNSHKSEE
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA