| Definition | Staphylococcus aureus subsp. aureus JH9, complete genome. |
|---|---|
| Accession | NC_009487 |
| Length | 2,906,700 |
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The map label for this gene is uvrA [H]
Identifier: 148267219
GI number: 148267219
Start: 856985
End: 859831
Strand: Direct
Name: uvrA [H]
Synonym: SaurJH9_0783
Alternate gene names: 148267219
Gene position: 856985-859831 (Clockwise)
Preceding gene: 148267218
Following gene: 148267220
Centisome position: 29.48
GC content: 35.55
Gene sequence:
>2847_bases ATGAAAGAACCATCCATAGTAGTAAAAGGTGCTCGTGCGCATAACTTGAAAGATATTGATATCGAACTACCTAAAAATAA ATTAATTGTTATGACAGGTTTATCTGGGTCAGGTAAATCGTCATTAGCATTCGATACTATATATGCTGAAGGACAACGAC GTTATGTTGAATCATTAAGTGCCTATGCGCGTCAATTTTTAGGCCAAATGGACAAACCAGATGTTGATACAATTGAAGGA TTATCGCCAGCAATTTCAATAGATCAAAAAACAACAAGTAAAAATCCAAGATCAACTGTAGCAACAGTAACAGAAATATA TGATTATATACGTTTGTTATATGCACGTGTTGGTAAACCTTACTGTCCAAATCACAATATAGAAATTGAATCGCAAACAG TACAACAAATGGTTGACCGCATTATGGAATTAGAGGCACGTACAAAGATTCAATTATTAGCACCTGTCATCGCTCATCGT AAAGGTAGTCATGAAAAGCTAATCGAAGATATTGGTAAAAAAGGTTATGTACGTTTAAGAATCGATGGCGAAATTGTTGA TGTAAATGATGTACCTACTTTAGATAAGAACAAGAATCATACAATAGAAGTTGTTGTAGACCGATTAGTTGTTAAAGATG GAATTGAAACACGACTAGCTGACTCTATAGAAACTGCGTTAGAGCTTTCAGAAGGACAATTAACAGTTGATGTCATTGAC GGGGAAGACCTTAAGTTTTCAGAAAGCCATGCTTGTCCTATATGTGGATTTTCAATCGGAGAGTTAGAACCAAGAATGTT TAGCTTTAACAGTCCTTTTGGTGCTTGTCCGACATGTGATGGCTTAGGCCAAAAGTTAACAGTCGATGTAGACTTGGTTG TTCCCGACAAAGATAAGACGCTAAACGAAGGTGCAATAGAACCTTGGATACCGACGAGTTCTGATTTTTATCCAACATTG TTAAAACGTGTTTGTGAAGTTTATAAAATCAATATGGATAAACCTTTTAAAAAGTTAACAGAACGTCAACGTGATATTTT ATTGTATGGTTCTGGTGACAAAGAAATTGAATTTACATTTACACAACGTCAAGGTGGTACTAGAAAACGAACAATGGTTT TCGAGGGTGTAGTTCCTAATATAAGTAGACGATTCCATGAATCTCCTTCAGAATATACACGTGAAATGATGAGTAAATAT ATGACCGAACTACCTTGTGAAACTTGTCATGGAAAGCGATTGAGTCGTGAAGCGTTATCTGTTTATGTAGGTGGTTTAAA TATTGGTGAAGTAGTCGAATATTCAATCAGTCAAGCGCTGAACTATTATAAAAACATTGATTTGTCAGAACAAGATCAAG CGATTGCAAATCAAATATTGAAAGAAATTATTTCCCGACTCACTTTTTTAAATAATGTGGGACTTGAATATTTAACGCTA AACAGAGCTTCAGGTACACTTTCAGGTGGTGAAGCACAACGTATTCGATTGGCAACGCAAATTGGGTCGCGTTTGACTGG TGTCTTATATGTATTAGATGAGCCATCAATTGGACTGCATCAAAGAGATAATGATCGATTAATTAATACACTTAAAGAAA TGAGAGATTTAGGAAATACTTTAATTGTAGTTGAACACGATGATGATACAATGCGTGCGGCTGATTACTTAGTGGATATA GGGCCTGGTGCTGGTGAACATGGAGGACAAATTGTGTCTAGTGGGACACCTCAAAAGGTAATGAAAGATAAAAAATCATT AACAGGACAATACTTGAGTGGTAAGAAACGTATTGACGTACCTGAATATCGCAGACCGGCTTCAGATCGTAAAATTTCTA TACGTGGAGCTAGAAGCAACAATCTTAAAGGGATTGATGTGGACATACCACTATCAATCATGACGGTTGTTACAGGTGTA TCAGGTTCTGGTAAAAGCTCATTAGTAAATGAAGTATTATACAAATCATTAGCTCAAAAAATTAATAAATCTAAAGTAAA GCCAGGATTGTACGATAAGATTGAAGGTATTGATCAACTTGATAAAATTATTGATATTGATCAATCACCGATAGGTAGAA CGCCACGCTCTAATCCAGCAACATATACTGGTGTGTTTGATGATATACGTGATGTGTTTGCGCAAACAAATGAAGCTAAA ATTCGAGGATATCAAAAAGGGCGTTTTAGTTTTAATGTAAAAGGTGGACGCTGTGAAGCTTGTAAAGGTGACGGTATTAT TAAAATTGAAATGCATTTTTTACCTGATGTTTATGTTCCTTGTGAAGTGTGTGATGGTAAACGATATAATCGTGAGACAC TAGAGGTTACTTACAAAGGTAAAAATATTGCTGACATTTTAGAAATGACTGTTGAAGAAGCAACACAATTTTTTGAAAAT ATTCCTAAGATTAAGCGCAAGTTACAAACACTAGTTGATGTTGGTCTTGGATACGTCACATTAGGTCAACAAGCTACAAC GTTATCAGGTGGTGAGGCTCAACGTGTGAAACTTGCATCTGAACTTCATAAACGTTCAACTGGTAAATCTATTTATATCC TAGACGAACCAACAACAGGGTTACATGTTGACGATATTAGCAGATTATTAAAAGTATTAAATCGATTAGTTGAAAATGGT GACACTGTTGTAATTATTGAACATAACCTAGATGTTATCAAAACAGCAGACTATATTATCGACTTAGGTCCTGAAGGTGG TAGTGGCGGTGGTACTATTGTTGCGACTGGCACACCCGAAGATATTGCTCAGACAAAGTCATCATATACAGGAAAGTATT TAAAAGAAGTACTTGAACGAGATAAACAAAATACTGAAGATAAATAA
Upstream 100 bases:
>100_bases GAAAAAGAAATGAAACAAGCAGCGAAAGATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAA AGCAGAAGGGTGACAAGTAA
Downstream 100 bases:
>100_bases GATTAAAAGAAGTGAAGGGTGTTGTAAATTTACCCTTCACTTCTTTTTATTAATTTAGTAATGAATAGTAGAAAGAAAAG ATGCGTAAAAAGAATTATGT
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 948; Mature: 948
Protein sequence:
>948_residues MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI GPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGV SGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
Sequences:
>Translated_948_residues MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI GPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGV SGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK >Mature_948_residues MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI GPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGV SGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=938, Percent_Identity=57.9957356076759, Blast_Score=1124, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 105370; Mature: 105370
Theoretical pI: Translated: 6.28; Mature: 6.28
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCCEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH AYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKP HHHHHHHCCCCCCCCCHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC YCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLR CCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEE IDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID ECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEEC GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKT CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCCC LNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTF CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEE TQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALS EECCCCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHH VYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL HEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNT ECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCE LIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDV EEEEECCCCHHHHHHHEEECCCCCCCCCCEECCCCCHHHHHHHHHHHCCHHHCCCCCCCC PEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQK CHHCCCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH INKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCHH IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKG CCCEECCEEEEEECCCEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCEEEEEEECC KNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLAS CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCHHHHHHHH ELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYII HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCEEE DLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK EECCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCC >Mature Secondary Structure MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCCEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH AYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKP HHHHHHHCCCCCCCCCHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC YCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLR CCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEE IDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID ECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEEC GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKT CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCCC LNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTF CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEE TQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALS EECCCCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHH VYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL HEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNT ECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCE LIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDV EEEEECCCCHHHHHHHEEECCCCCCCCCCEECCCCCHHHHHHHHHHHCCHHHCCCCCCCC PEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQK CHHCCCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH INKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCHH IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKG CCCEECCEEEEEECCCEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCEEEEEEECC KNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLAS CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCHHHHHHHH ELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYII HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCEEE DLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK EECCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA