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The map label for this gene is ispD1 [H]

Identifier: 148266676

GI number: 148266676

Start: 286701

End: 287417

Strand: Direct

Name: ispD1 [H]

Synonym: SaurJH9_0236

Alternate gene names: 148266676

Gene position: 286701-287417 (Clockwise)

Preceding gene: 148266675

Following gene: 148266677

Centisome position: 9.86

GC content: 32.91

Gene sequence:

>717_bases
ATGATTTATGCAGGTATTTTAGCAGGAGGTATTGGTTCGAGAATGGGGAACGTGCCATTACCAAAACAATTTTTAGATAT
TGATAATAAACCGATTTTAATCCATACAATTGAGAAGTTCATTTTAGTGAGTGAATTTAATGAGATTATTATCGCAACGC
CAGCACAGTGGATTTCCCATACACAGGATATTTTAAAAAAATATAACATTACAGATCAACGTGTCAAAGTAGTTGCAGGT
GGTACGGATCGAAACGAAACAATTATGAACATTATCGACCATATTCGCAATGTAAATGGAATTAATAATGATGATGTGAT
TGTAACTCATGATGCCGTAAGACCATTTTTAACTCAACGTATTATTAAAGAGAACATTGAAGTAGCAGCAAAATATGGTG
CAGTAGATACAGTCATTGAAGCAATTGATACGATTGTAATGTCTAAAGATAAACAGAACATACACAGTATCCCTGTAAGG
AATGAAATGTATCAAGGCCAAACACCACAATCATTTAATATTAAATTATTACAAGATAGTTATCGCGCCTTAAGTAGTGA
ACAAAAAGAAATCTTATCAGATGCATGTAAAATAATTGTCGAATCTGGACATGCAGTTAAATTGGTACGTGGAGAACTAT
ACAACATTAAAGTGACAACACCGTATGATTTAAAAGTAGCAAATGCCATTATTCAAGGTGATATTGCCGATGATTAA

Upstream 100 bases:

>100_bases
ATTAATAAAAGAGGCAAGTGAGCAATAGGTTAGGCTTATGTGCGGGCATAGGTCAGTAATGTATAAATGGAAATGATGTA
ATGACAGAATGGAGGACAAC

Downstream 100 bases:

>100_bases
TCAAGTATATCAACTCGTTGCACCGAGACAGTTCGACGTCACATATAATAATGTTGATATTTATGGTAATCATGTCATCG
TAAGACCTTTATACTTGTCT

Product: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Products: NA

Alternate protein names: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase 1; MEP cytidylyltransferase 1; MCT 1 [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAG
GTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVR
NEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD

Sequences:

>Translated_238_residues
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAG
GTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVR
NEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
>Mature_238_residues
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAG
GTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVR
NEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD

Specific function: Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) [H]

COG id: COG1211

COG function: function code I; 4-diphosphocytidyl-2-methyl-D-erithritol synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispD family [H]

Homologues:

Organism=Homo sapiens, GI157412259, Length=241, Percent_Identity=26.1410788381743, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI157671913, Length=230, Percent_Identity=24.7826086956522, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1789104, Length=232, Percent_Identity=26.7241379310345, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001228
- InterPro:   IPR018294 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.60 [H]

Molecular weight: Translated: 26575; Mature: 26575

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01295 ISPD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISH
CEEEEEECCCHHHHCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHCCCCEEEECCHHHHHH
TQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQR
HHHHHHHCCCCCHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHH
IIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVRNEMYQGQTPQSFNIKLLQDS
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHCCCCCCCCEEEEHHHH
YRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISH
CEEEEEECCCHHHHCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHCCCCEEEECCHHHHHH
TQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQR
HHHHHHHCCCCCHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHH
IIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVRNEMYQGQTPQSFNIKLLQDS
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHCCCCCCCCEEEEHHHH
YRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA