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The map label for this gene is uhpT [H]

Identifier: 148266646

GI number: 148266646

Start: 247050

End: 248429

Strand: Direct

Name: uhpT [H]

Synonym: SaurJH9_0206

Alternate gene names: 148266646

Gene position: 247050-248429 (Clockwise)

Preceding gene: 148266644

Following gene: 148266650

Centisome position: 8.5

GC content: 36.16

Gene sequence:

>1380_bases
ATGAACTTTTTTGATATCCATAAGATTCCGAACAAAGGCATTCCATTATCGGTACAACGTAAATTATGGCTTAGAAACTT
CATGCAAGCTTTCTTTGTAGTGTTCTTTGTTTATATGGCTATGTATTTAATTCGAAACAACTTTAAGGCGGCCCAACCGT
TTTTAAAAGAGGAAATTGGATTATCTACATTAGAACTTGGTTATATCGGATTAGCATTTAGTATCACGTACGGTTTAGGG
AAAACATTACTTGGATATTTTGTCGATGGACGTAACACAAAACGTATTATCTCGTTCTTACTTATCTTATCTGCGATTAC
AGTTTTAATTATGGGATTTGTTTTAAGTTACTTTGGTTCTGTAATGGGATTATTAATTGTACTTTGGGGACTTAACGGGG
TGTTCCAATCAGTTGGTGGACCTGCAAGTTATTCAACGATTTCAAGATGGGCGCCAAGAACGAAACGTGGCCGATACTTA
GGATTTTGGAATACATCACATAATATCGGTGGTGCCATTGCAGGTGGTGTTGCACTTTGGGGTGCTAATGTATTCTTCCA
TGGAAATGTTATAGGGATGTTCATTTTCCCATCGGTGATTGCATTACTTATTGGTATCGCAACATTATTTATCGGAAAAG
ATGATCCAGAAGAATTAGGATGGAATCGTGCTGAAGAAATTTGGGAAGAGCCGGTCGATAAAGAAAATATTGATTCTCAA
GGTATGACGAAATGGGAGATCTTTAAAAAATATATCCTGGGAAATCCTGTTATATGGATTCTATGTGTTTCAAACGTCTT
TGTATACATTGTACGAATCGGTATTGATAACTGGGCACCGTTATATGTGTCAGAGCATTTACACTTTAGTAAAGGCGATG
CAGTTAATACGATATTCTACTTTGAAATTGGTGCATTAGTTGCAAGTTTATTATGGGGCTACGTATCAGACTTATTAAAA
GGTCGTCGTGCAATTGTAGCTATTGGCTGTATGTTTATGATTACATTTGTTGTCTTATTCTACACAAATGCTACAAGTGT
CATGATGGTTAACATTTCATTGTTTGCATTAGGTGCGTTAATCTTTGGTCCGCAATTATTAATTGGTGTATCATTGACTG
GTTTTGTTCCTAAAAATGCCATCAGTGTAGCAAACGGAATGACAGGTTCATTCGCGTATCTATTCGGTGACTCAATGGCG
AAAGTTGGTTTGGCGGCTATTGCTGATCCAACACGTAACGGTTTAAACATCTTTGGATATACATTAAGTGGATGGACAGA
TGTTTTCATCGTCTTCTATGTTGCATTATTCCTAGGCATGATTCTATTAGGAATCGTTGCTTTCTATGAAGAAAAGAAAA
TTAGAAGTTTAAAAATTTAA

Upstream 100 bases:

>100_bases
TTATGTTCAGTATTTTGGATAATTTAATAATTTTAAGGATATTAAGCGCTTACACCGACGTGATATATTTGGCTTAACGA
AAATGATTGAGGTGACAGAG

Downstream 100 bases:

>100_bases
TATAAATCGGATTAAAAGTATCGCCAATCTATTGCAATATAGTTGGCAATCCTGCCCCGACGGCATGTGCGTGAAGAGAT
GAAAGATACTGCTTCTACCC

Product: sugar phosphate antiporter

Products: Proton [Cytoplasm]; glucose-6-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG
KTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL
GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ
GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLK
GRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMA
KVGLAAIADPTRNGLNIFGYTLSGWTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI

Sequences:

>Translated_459_residues
MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG
KTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL
GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ
GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLK
GRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMA
KVGLAAIADPTRNGLNIFGYTLSGWTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI
>Mature_459_residues
MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLG
KTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL
GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ
GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLK
GRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMA
KVGLAAIADPTRNGLNIFGYTLSGWTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI223717983, Length=418, Percent_Identity=24.4019138755981, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI38093649, Length=418, Percent_Identity=24.1626794258373, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI256219598, Length=382, Percent_Identity=23.0366492146597, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4503847, Length=382, Percent_Identity=23.0366492146597, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI256219483, Length=382, Percent_Identity=23.0366492146597, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI256219543, Length=289, Percent_Identity=23.5294117647059, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI46361976, Length=282, Percent_Identity=24.113475177305, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI2367259, Length=462, Percent_Identity=51.0822510822511, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1788573, Length=456, Percent_Identity=31.5789473684211, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082310, Length=440, Percent_Identity=30, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI2367193, Length=379, Percent_Identity=24.5382585751979, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082320, Length=345, Percent_Identity=22.3188405797101, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17542316, Length=463, Percent_Identity=24.4060475161987, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI133930953, Length=484, Percent_Identity=23.5537190082645, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI133901856, Length=465, Percent_Identity=24.3010752688172, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI133901854, Length=465, Percent_Identity=24.3010752688172, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17564204, Length=386, Percent_Identity=22.7979274611399, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17564202, Length=386, Percent_Identity=22.7979274611399, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24656866, Length=485, Percent_Identity=21.0309278350515, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45550478, Length=485, Percent_Identity=21.0309278350515, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24656861, Length=485, Percent_Identity=21.0309278350515, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50996; Mature: 50996

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
LSTLELGYIGLAFSITYGLGKTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYLGFWNTSHNIGGAIAGGVALW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
GANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHCCCCCCCCCCC
GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFY
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEHH
FEIGALVASLLWGYVSDLLKGRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALGAL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
IFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMAKVGLAAIADPTRNGLNIFGY
HHCCHHHHHEEHCCCCCCHHHHHHCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCEEEEE
TLSGWTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLIRNNFKAAQPFLKEEIG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
LSTLELGYIGLAFSITYGLGKTLLGYFVDGRNTKRIISFLLILSAITVLIMGFVLSYFGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYLGFWNTSHNIGGAIAGGVALW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
GANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEELGWNRAEEIWEEPVDKENIDSQ
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHCCCCCCCCCCC
GMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGIDNWAPLYVSEHLHFSKGDAVNTIFY
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEHH
FEIGALVASLLWGYVSDLLKGRRAIVAIGCMFMITFVVLFYTNATSVMMVNISLFALGAL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
IFGPQLLIGVSLTGFVPKNAISVANGMTGSFAYLFGDSMAKVGLAAIADPTRNGLNIFGY
HHCCHHHHHEEHCCCCCCHHHHHHCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCEEEEE
TLSGWTDVFIVFYVALFLGMILLGIVAFYEEKKIRSLKI
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glucose-6-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glucose-6-phosphate [Periplasm] = Proton [Cytoplasm] + glucose-6-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]