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The map label for this gene is ggt [H]

Identifier: 148266634

GI number: 148266634

Start: 233153

End: 235159

Strand: Direct

Name: ggt [H]

Synonym: SaurJH9_0194

Alternate gene names: 148266634

Gene position: 233153-235159 (Clockwise)

Preceding gene: 148266633

Following gene: 148266637

Centisome position: 8.02

GC content: 37.82

Gene sequence:

>2007_bases
ATGGTCATTAACTTAAATGACAAACAGACAAAAACATCTAAAGAAGGGTTAATTTCCGTATCACATCCTCTTGCGGCTAA
AATTGGTAAGGATGTATTAGATCAAGGTGGCAACGCCATGGATGCCGTGATTGCAATTCAACTGGCATTGAATGTGGTAG
AACCATTTGCATCAGGTATTGGTGGTGGCGGGTACTTGCTATATTATGAGCAAAGTACTGGCAGTATAACTGCGTTTGAT
GCACGTGAGACAGCACCTGAACATGTAGACAAACAATTTTATCTAGATGATTCAGGCGAATATAAATCATTTTTTGATAT
GACTACACATGGTAAAACTGTCGCTGTGCCAGCAATTCCAAAGCTGTTTGATTATATTCACAAGCGTTATGCTAAATTGT
CATTGGAAGATTTAATTAATCCTGCAATTGAACTAGCCATTGAAGGTCATGCAGCCAATTGGGCTACTGAAAAATATTCG
CGCCAGCAACACGCACGATTGACAAAGTATCATGAAACGGCACAAGTATTTACGCATGAAAATCAATATTGGCGTGAAGG
TGATTGGATTGTACAACCCGAATTAGGTAAGACATTTCAAATATTAAGAGAACAAGGGTTTAATGCATTTTATAAAGGTG
ACATTGCGAAACAATTAGTCAATGTTGTTAAAGCATGTGGTGGGACAATCATTTTAGAGGATCTAGCCAATTATGACATT
CAGATTAAAGCGCCAATCAGTGCGACATTTAAAGACTATGACATTTATTCAATGGGACCATCTAGTTCTGGCGGTATCAC
GGTCATTCAAATATTGAAGTTATTAGAACATGTCGATTTACCATCTATGGGTCCAAGATCTGTCGATTACTTGCATCATT
TGATACAAGCGATGCATTTAGCATATAGTGATCGCGCGCAATACTTGGCGGATGATAATTTTCATGAGGTGCCTGTACAG
TCATTAATTGATGACGATTATTTAAAAGCACGCAGTACGCTCATTAATAGCAATAAAGCAAATATTGATATAGAGCATGG
TGTTGTGTCTGATTGCATTAGTCATACAGATGTTGAAGAAAATCATACCGAAACAACTCATTTTTGTGTGATTGATAAGG
AAGGTAATATTGCTTCATTTACGACATCAATTGGTATGATTTATGGTTCAGGTATCACGATTCCAGGCTACGGTGTGTTA
TTGAATACGACAATGGATGGCTTTGATGTAGTAGATGGTGGTATTAACGAAATTGCACCATATAAACGACCACTAAGTAA
CATGGCTCCAACGATTGTGATGCATCACGGGAAGCCGATATTAACAGTAGGTGCACCTGGTGCCATAAGTATCATTGCTA
GTGTTGCGCAAACATTAATCAATGTATTAGTGTTTGGCATGGATATTCAGCAGGCTATAGATGAACCTAGAATTTATAGT
AGCCATCCTAATCGCATTGAATGGGAGCCTCAATTTTCACAATCTACAATATTAGCATTGATTGCACGTGGACATGCAAT
GGAACATAAACCAGATGCCTATATTGGAGATGTACATGGGTTACAGGTTGACTTGAATACACGTGACGCGTCGGGAGGTG
CTGATGATACGAGGGAAGGCACAGTGATAGGTGGCGATGTATTATCAATTAGAAAACAACCATTACCTAGTCCGAAAATA
TACGATAATGACACCCATCGAGTATATTTCAATGATATGCAGTTGCCATTATATGCTGAACAAGTGCGGTGGATGCATGA
CAAATATTGGGTTGATGAAAGTGTTATTAGAATCATTTTCCCTGAAGTTAGTGTGCATATTGAAGATTTAAGAAGTTATG
AAATCGCCGGAAAAAATTATATAGATATTGCCTGGTTGGCACGGAAGAAAGGTTATCAAGTTACCTTAAAGGATGACAGT
TTATACTTAACTGATGAAACATATCATTCAGTGAAAGCAAACACAAATGCATACTATAGATATGATCGAGATAGTATCAC
AAGATAA

Upstream 100 bases:

>100_bases
GTCGATACTGGTAACGAGCAACGTCAAGATTTAGAAAAAGTAGAAAAAGCCATTAATCAATAATGTTTTAAATATTTAAC
AGAAAGTAGGAGGATATAGT

Downstream 100 bases:

>100_bases
TTTATGTATTTGATATATAGTTTGAAGTGGATTTTGATTTTTGTTGAACGAAAGGGTTCGATTTCAAACTTTAGAGTGAT
GCTTGAGTGTAGTAATGTTG

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVIAIQLALNVVEPFASGIGGGGYLLYYEQSTGSITAFD
ARETAPEHVDKQFYLDDSGEYKSFFDMTTHGKTVAVPAIPKLFDYIHKRYAKLSLEDLINPAIELAIEGHAANWATEKYS
RQQHARLTKYHETAQVFTHENQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQLVNVVKACGGTIILEDLANYDI
QIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLEHVDLPSMGPRSVDYLHHLIQAMHLAYSDRAQYLADDNFHEVPVQ
SLIDDDYLKARSTLINSNKANIDIEHGVVSDCISHTDVEENHTETTHFCVIDKEGNIASFTTSIGMIYGSGITIPGYGVL
LNTTMDGFDVVDGGINEIAPYKRPLSNMAPTIVMHHGKPILTVGAPGAISIIASVAQTLINVLVFGMDIQQAIDEPRIYS
SHPNRIEWEPQFSQSTILALIARGHAMEHKPDAYIGDVHGLQVDLNTRDASGGADDTREGTVIGGDVLSIRKQPLPSPKI
YDNDTHRVYFNDMQLPLYAEQVRWMHDKYWVDESVIRIIFPEVSVHIEDLRSYEIAGKNYIDIAWLARKKGYQVTLKDDS
LYLTDETYHSVKANTNAYYRYDRDSITR

Sequences:

>Translated_668_residues
MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVIAIQLALNVVEPFASGIGGGGYLLYYEQSTGSITAFD
ARETAPEHVDKQFYLDDSGEYKSFFDMTTHGKTVAVPAIPKLFDYIHKRYAKLSLEDLINPAIELAIEGHAANWATEKYS
RQQHARLTKYHETAQVFTHENQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQLVNVVKACGGTIILEDLANYDI
QIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLEHVDLPSMGPRSVDYLHHLIQAMHLAYSDRAQYLADDNFHEVPVQ
SLIDDDYLKARSTLINSNKANIDIEHGVVSDCISHTDVEENHTETTHFCVIDKEGNIASFTTSIGMIYGSGITIPGYGVL
LNTTMDGFDVVDGGINEIAPYKRPLSNMAPTIVMHHGKPILTVGAPGAISIIASVAQTLINVLVFGMDIQQAIDEPRIYS
SHPNRIEWEPQFSQSTILALIARGHAMEHKPDAYIGDVHGLQVDLNTRDASGGADDTREGTVIGGDVLSIRKQPLPSPKI
YDNDTHRVYFNDMQLPLYAEQVRWMHDKYWVDESVIRIIFPEVSVHIEDLRSYEIAGKNYIDIAWLARKKGYQVTLKDDS
LYLTDETYHSVKANTNAYYRYDRDSITR
>Mature_668_residues
MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVIAIQLALNVVEPFASGIGGGGYLLYYEQSTGSITAFD
ARETAPEHVDKQFYLDDSGEYKSFFDMTTHGKTVAVPAIPKLFDYIHKRYAKLSLEDLINPAIELAIEGHAANWATEKYS
RQQHARLTKYHETAQVFTHENQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQLVNVVKACGGTIILEDLANYDI
QIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLEHVDLPSMGPRSVDYLHHLIQAMHLAYSDRAQYLADDNFHEVPVQ
SLIDDDYLKARSTLINSNKANIDIEHGVVSDCISHTDVEENHTETTHFCVIDKEGNIASFTTSIGMIYGSGITIPGYGVL
LNTTMDGFDVVDGGINEIAPYKRPLSNMAPTIVMHHGKPILTVGAPGAISIIASVAQTLINVLVFGMDIQQAIDEPRIYS
SHPNRIEWEPQFSQSTILALIARGHAMEHKPDAYIGDVHGLQVDLNTRDASGGADDTREGTVIGGDVLSIRKQPLPSPKI
YDNDTHRVYFNDMQLPLYAEQVRWMHDKYWVDESVIRIIFPEVSVHIEDLRSYEIAGKNYIDIAWLARKKGYQVTLKDDS
LYLTDETYHSVKANTNAYYRYDRDSITR

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=540, Percent_Identity=28.3333333333333, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI73915090, Length=540, Percent_Identity=28.3333333333333, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI73915096, Length=540, Percent_Identity=28.3333333333333, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI73915094, Length=540, Percent_Identity=28.3333333333333, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI113429324, Length=538, Percent_Identity=27.6951672862454, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI113429326, Length=544, Percent_Identity=27.9411764705882, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI153266885, Length=517, Percent_Identity=25.531914893617, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI153266901, Length=517, Percent_Identity=25.3384912959381, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI153266907, Length=516, Percent_Identity=23.8372093023256, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI109148539, Length=517, Percent_Identity=24.9516441005803, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI30581157, Length=189, Percent_Identity=32.8042328042328, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI30581155, Length=189, Percent_Identity=32.8042328042328, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI218505805, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789856, Length=512, Percent_Identity=34.5703125, Blast_Score=308, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI212646519, Length=504, Percent_Identity=30.5555555555556, Blast_Score=188, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI193208245, Length=508, Percent_Identity=31.1023622047244, Blast_Score=188, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI193208247, Length=508, Percent_Identity=31.1023622047244, Blast_Score=188, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI72000294, Length=504, Percent_Identity=30.5555555555556, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17506189, Length=522, Percent_Identity=26.8199233716475, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17542894, Length=515, Percent_Identity=27.7669902912621, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI72001497, Length=264, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72001495, Length=264, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323330, Length=510, Percent_Identity=29.8039215686275, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24642670, Length=522, Percent_Identity=28.1609195402299, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24642666, Length=522, Percent_Identity=28.1609195402299, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI45551474, Length=522, Percent_Identity=28.1609195402299, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI161077878, Length=522, Percent_Identity=28.1609195402299, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI161077880, Length=522, Percent_Identity=28.1609195402299, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI161077496, Length=525, Percent_Identity=26.8571428571429, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI18859893, Length=538, Percent_Identity=27.6951672862454, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI18859741, Length=523, Percent_Identity=27.151051625239, Blast_Score=153, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 74609; Mature: 74609

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVIAIQLALNVVEPFASGI
CEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
GGGGYLLYYEQSTGSITAFDARETAPEHVDKQFYLDDSGEYKSFFDMTTHGKTVAVPAIP
CCCEEEEEEECCCCCEEEECCCCCCHHHCCCEEEECCCCCCCHHEEEECCCCEEECCCHH
KLFDYIHKRYAKLSLEDLINPAIELAIEGHAANWATEKYSRQQHARLTKYHETAQVFTHE
HHHHHHHHHHHHCCHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECC
NQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQLVNVVKACGGTIILEDLANYDI
CCCEECCCEEECCCCCHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCEEEEEHHHCCCE
QIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLEHVDLPSMGPRSVDYLHHLIQAMHL
EEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AYSDRAQYLADDNFHEVPVQSLIDDDYLKARSTLINSNKANIDIEHGVVSDCISHTDVEE
HHHCCHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCC
NHTETTHFCVIDKEGNIASFTTSIGMIYGSGITIPGYGVLLNTTMDGFDVVDGGINEIAP
CCCCCEEEEEEECCCCEEEEEHHEEEEEECCCCCCCCCEEEECCCCCCHHCCCCHHHCCC
YKRPLSNMAPTIVMHHGKPILTVGAPGAISIIASVAQTLINVLVFGMDIQQAIDEPRIYS
CCCCHHHCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
SHPNRIEWEPQFSQSTILALIARGHAMEHKPDAYIGDVHGLQVDLNTRDASGGADDTREG
CCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCC
TVIGGDVLSIRKQPLPSPKIYDNDTHRVYFNDMQLPLYAEQVRWMHDKYWVDESVIRIIF
EEECCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEE
PEVSVHIEDLRSYEIAGKNYIDIAWLARKKGYQVTLKDDSLYLTDETYHSVKANTNAYYR
CCCEEEHHHHHHEEECCCCEEEEEEEECCCCCEEEEECCCEEEECCHHHHEECCCCEEEE
YDRDSITR
ECCCCCCC
>Mature Secondary Structure
MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVIAIQLALNVVEPFASGI
CEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
GGGGYLLYYEQSTGSITAFDARETAPEHVDKQFYLDDSGEYKSFFDMTTHGKTVAVPAIP
CCCEEEEEEECCCCCEEEECCCCCCHHHCCCEEEECCCCCCCHHEEEECCCCEEECCCHH
KLFDYIHKRYAKLSLEDLINPAIELAIEGHAANWATEKYSRQQHARLTKYHETAQVFTHE
HHHHHHHHHHHHCCHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECC
NQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQLVNVVKACGGTIILEDLANYDI
CCCEECCCEEECCCCCHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCEEEEEHHHCCCE
QIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLEHVDLPSMGPRSVDYLHHLIQAMHL
EEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AYSDRAQYLADDNFHEVPVQSLIDDDYLKARSTLINSNKANIDIEHGVVSDCISHTDVEE
HHHCCHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCC
NHTETTHFCVIDKEGNIASFTTSIGMIYGSGITIPGYGVLLNTTMDGFDVVDGGINEIAP
CCCCCEEEEEEECCCCEEEEEHHEEEEEECCCCCCCCCEEEECCCCCCHHCCCCHHHCCC
YKRPLSNMAPTIVMHHGKPILTVGAPGAISIIASVAQTLINVLVFGMDIQQAIDEPRIYS
CCCCHHHCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
SHPNRIEWEPQFSQSTILALIARGHAMEHKPDAYIGDVHGLQVDLNTRDASGGADDTREG
CCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCC
TVIGGDVLSIRKQPLPSPKIYDNDTHRVYFNDMQLPLYAEQVRWMHDKYWVDESVIRIIF
EEECCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEE
PEVSVHIEDLRSYEIAGKNYIDIAWLARKKGYQVTLKDDSLYLTDETYHSVKANTNAYYR
CCCEEEHHHHHHEEECCCCEEEEEEEECCCCCEEEEECCCEEEECCHHHHEECCCCEEEE
YDRDSITR
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA