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The map label for this gene is lytM [H]

Identifier: 148266637

GI number: 148266637

Start: 237269

End: 237847

Strand: Direct

Name: lytM [H]

Synonym: SaurJH9_0197

Alternate gene names: 148266637

Gene position: 237269-237847 (Clockwise)

Preceding gene: 148266634

Following gene: 148266638

Centisome position: 8.16

GC content: 35.92

Gene sequence:

>579_bases
ATGACAAAGCGACCAAAACGTATTTTGGCAACAATTATCATTTTTCTTTCACTATTATTTACGATTATTTATATAGATGA
CATTCAAAAATGGTTTAACCAATATACCGATAAATTGACACAAAATCATAAAGGACAAGGACACTCAAAATGGGAAGACT
TTTTTAGAGGGAGTAGGATTACTGAGACTTTTGGCAAATATCAACATTCACCATTTGATGGTAAGCATTATGGCATTGAT
TTTGCATTGCCAAAAGGTACACCAATTAAAGCGCCGACGAATGGTAAAGTAACACGTATCTTTAATAATGAATTAGGCGG
CAAGGTATTACAGATTGCCGAAGACAATGGAGAATATCACCAGTGGTATCTACACTTAGACAAATATAATGTCAAAGTAG
GTGATCGAGTTAAAGCAGGTGATATTATTGCATATTCAGGCAATACAGGTAAACAAACGACAGGCGCACATTTACATTTT
CAAAGAATGAAGGGTGGCGTAGGTAATGCATATGCAGAAGATCCTAAACCGTTTATCGAGCAGTTACCTGATGGGGAACG
TAGCCTATATGATTTGTAG

Upstream 100 bases:

>100_bases
TATTTGGCAGTACTACTAAAGTATGAGTGCATTTAATTATGAAATAGTTGATTTAGAATATATACTTAATACCCAAAATA
TATGAAGGATGGATGCCACT

Downstream 100 bases:

>100_bases
TTATAGAAGAGTGCCCGCAGTCTAAAAAATTAAGCAATCATTGTGTGAGTATGATACTTACATAATGGTTGCTTTTTTCA
ATGAAAATCGTAATGCTAAG

Product: peptidase M23B

Products: NA

Alternate protein names: Autolysin lytM [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNHKGQGHSKWEDFFRGSRITETFGKYQHSPFDGKHYGID
FALPKGTPIKAPTNGKVTRIFNNELGGKVLQIAEDNGEYHQWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHF
QRMKGGVGNAYAEDPKPFIEQLPDGERSLYDL

Sequences:

>Translated_192_residues
MTKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNHKGQGHSKWEDFFRGSRITETFGKYQHSPFDGKHYGID
FALPKGTPIKAPTNGKVTRIFNNELGGKVLQIAEDNGEYHQWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHF
QRMKGGVGNAYAEDPKPFIEQLPDGERSLYDL
>Mature_191_residues
TKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNHKGQGHSKWEDFFRGSRITETFGKYQHSPFDGKHYGIDF
ALPKGTPIKAPTNGKVTRIFNNELGGKVLQIAEDNGEYHQWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHFQ
RMKGGVGNAYAEDPKPFIEQLPDGERSLYDL

Specific function: Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

Organism=Escherichia coli, GI87081989, Length=106, Percent_Identity=39.622641509434, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: =3.4.24.75 [H]

Molecular weight: Translated: 21965; Mature: 21834

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNHKGQGHSKWEDFFRGSRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHH
TETFGKYQHSPFDGKHYGIDFALPKGTPIKAPTNGKVTRIFNNELGGKVLQIAEDNGEYH
HHHHHHHCCCCCCCCEECEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCEE
QWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHFQRMKGGVGNAYAEDPKPFIE
EEEEEEECEEEEECCEECCCCEEEECCCCCCCCCCCCEEHHHHCCCCCCCCCCCCCHHHH
QLPDGERSLYDL
HCCCCCHHHCCC
>Mature Secondary Structure 
TKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNHKGQGHSKWEDFFRGSRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHH
TETFGKYQHSPFDGKHYGIDFALPKGTPIKAPTNGKVTRIFNNELGGKVLQIAEDNGEYH
HHHHHHHCCCCCCCCEECEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCEE
QWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHFQRMKGGVGNAYAEDPKPFIE
EEEEEEECEEEEECCEECCCCEEEECCCCCCCCCCCCEEHHHHCCCCCCCCCCCCCHHHH
QLPDGERSLYDL
HCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9171409; 8095258; 10220159; 12791130 [H]