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The map label for this gene is rocD1 [H]

Identifier: 148266610

GI number: 148266610

Start: 202989

End: 204173

Strand: Reverse

Name: rocD1 [H]

Synonym: SaurJH9_0170

Alternate gene names: 148266610

Gene position: 204173-202989 (Counterclockwise)

Preceding gene: 148266611

Following gene: 148266609

Centisome position: 7.02

GC content: 37.55

Gene sequence:

>1185_bases
ATGAATTCAATCATTGAATTAACTGATTATTATAGCTCTAATAATTATGCACCACTTAAGCTTGTCATTTCTAAAGGTAA
AGGTGTCAAAGTTTGGGATACTGATGGCAAACAATATATAGATTGCATTTCGGGTTTTTCAGTTGCAAACCAAGGCCATT
GTCATCCAACAATTGTTAAAGCGATGACAGAACAAGCTTCAAAGTTGTCTATCATTTCACGTGTCCTTTATAGTGACAAT
CTCGGGAAATGGGAAGAAAAAATTTGTCATCTTGCTAAGAAAGACAAAGTACTCTCCCTTAACTCTGGTACTGAAGCTGT
TGAAGCAGCCATTAAAATTGCTAGAAAATGGGGCTCTGAAGTTAAAGGCATTACTGACGGACAAGTTGAAATCATCGCTA
TGAATAACAATTTTCACGGTCGTACACTTGGCTCATTATCACTATCTAACCACGACGCATATAAAGCAGGATTTCACCCC
CTACTTCAAGGCACTACAACTGTAGATTTTGGAGACATTGAACAATTAACACAAGCTATTTCACCGAATACAGCAGCAAT
TATTTTGGAACCAATTCAAGGTGAAGGTGGCGTTAATATACCACCGAAAGGATATATTCAAGCTGTGCGTCAACTATGTG
ATAAACATCAAATATTAATGATTGCAGATGAAATTCAAGTTGGTCTTGGTAGAACTGGGAAATGGTTTGCGATGGAATGG
GAACAAGTTGTTCCAGACATTTATATTTTAGGTAAGGCATTGGGTGGCGGCTTATACCCTGTATCTGCTGTACTTGCAAA
TAATGATGTCATGCGTGTTCTAACACCAGGTACACATGGTTCAACATTTGGTGGTAACCCTTTAGCCATTGCAATATCGA
CGGCAGCGCTTGATGTACTTAAAGATGAACAACTGGTTGAACGATCAGAACGCTTAGGTTCATTTTTATTAAAAGCGTTG
CTACAACTTAAACATCCTAGTATTAAAGAAATTAGAGGTCGTGGTTTATTTATAGGCATAGAGCTTAACACAGATGCTGC
ACCTTTTGTGGATCAACTGATTCAACGTGGAATCTTATGCAAAGACACGCATCGTACTATCATTCGATTGTCTCCACCTC
TAGTTATTGATAAAGAGGAAATCCATCAAATTGTTGCAGCTTTTCAAGACGTTTTTAAAAATTAA

Upstream 100 bases:

>100_bases
ATCTTTATATTATTAAATTTACATTTGACACTTATATTGAACAACTGTAATATATTAATATTAATTCTTTAAATTGTATA
AATATAAAGGAGGGAGACCG

Downstream 100 bases:

>100_bases
CAATTAATCATTTATATATGACATAGGAGGGATTCATGATGATTACAGTAGGTATCGTTGGCGGTAGCGGTTATGGCGCA
ATTGAATTAATTCGATTGTT

Product: ornithine aminotransferase

Products: NA

Alternate protein names: OAT 1; Ornithine--oxo-acid aminotransferase 1 [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVKAMTEQASKLSIISRVLYSDN
LGKWEEKICHLAKKDKVLSLNSGTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHP
LLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILMIADEIQVGLGRTGKWFAMEW
EQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVLKDEQLVERSERLGSFLLKAL
LQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVFKN

Sequences:

>Translated_394_residues
MNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVKAMTEQASKLSIISRVLYSDN
LGKWEEKICHLAKKDKVLSLNSGTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHP
LLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILMIADEIQVGLGRTGKWFAMEW
EQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVLKDEQLVERSERLGSFLLKAL
LQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVFKN
>Mature_394_residues
MNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVKAMTEQASKLSIISRVLYSDN
LGKWEEKICHLAKKDKVLSLNSGTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHP
LLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILMIADEIQVGLGRTGKWFAMEW
EQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVLKDEQLVERSERLGSFLLKAL
LQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVFKN

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=389, Percent_Identity=45.5012853470437, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI284507298, Length=289, Percent_Identity=46.7128027681661, Blast_Score=271, Evalue=7e-73,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=31.0262529832936, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI37574042, Length=406, Percent_Identity=30.5418719211823, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI13994255, Length=453, Percent_Identity=28.476821192053, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI226442709, Length=372, Percent_Identity=30.1075268817204, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI226442705, Length=411, Percent_Identity=29.1970802919708, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=23.4192037470726, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=23.4192037470726, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=23.4192037470726, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI145693181, Length=372, Percent_Identity=39.7849462365591, Blast_Score=260, Evalue=9e-71,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=35.9580052493438, Blast_Score=257, Evalue=8e-70,
Organism=Escherichia coli, GI1788044, Length=379, Percent_Identity=37.467018469657, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=35.4430379746835, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=32.6633165829146, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=29.126213592233, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786349, Length=321, Percent_Identity=31.4641744548287, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=383, Percent_Identity=44.9086161879896, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25144274, Length=385, Percent_Identity=36.8831168831169, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI32564660, Length=421, Percent_Identity=30.166270783848, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71981843, Length=171, Percent_Identity=40.9356725146199, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=29.3706293706294, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17541228, Length=413, Percent_Identity=27.1186440677966, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6323470, Length=399, Percent_Identity=43.3583959899749, Blast_Score=327, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6324432, Length=403, Percent_Identity=33.4987593052109, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=436, Percent_Identity=27.5229357798165, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=375, Percent_Identity=26.9333333333333, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=47.6190476190476, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI161085790, Length=433, Percent_Identity=27.9445727482679, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574759, Length=416, Percent_Identity=28.6057692307692, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21356575, Length=431, Percent_Identity=30.1624129930394, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=25.9953161592506, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=25.9953161592506, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=25.9953161592506, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 43057; Mature: 43057

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVK
CCCCEEEHHHHCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHH
AMTEQASKLSIISRVLYSDNLGKWEEKICHLAKKDKVLSLNSGTEAVEAAIKIARKWGSE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCHH
VKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHPLLQGTTTVDFGDIEQLTQAI
CCCCCCCCEEEEEECCCCCCCEECEEECCCCCCHHHCCHHHHCCCCEECCCCHHHHHHHH
SPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILMIADEIQVGLGRTGKWFAMEW
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEEEH
EQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVL
HHHCCHHEEEHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEHHHHHHH
KDEQLVERSERLGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILC
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCEE
KDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVFKN
ECCCCEEEEECCCEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVK
CCCCEEEHHHHCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHH
AMTEQASKLSIISRVLYSDNLGKWEEKICHLAKKDKVLSLNSGTEAVEAAIKIARKWGSE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCHH
VKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHPLLQGTTTVDFGDIEQLTQAI
CCCCCCCCEEEEEECCCCCCCEECEEECCCCCCHHHCCHHHHCCCCEECCCCHHHHHHHH
SPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILMIADEIQVGLGRTGKWFAMEW
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEEEH
EQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVL
HHHCCHHEEEHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEHHHHHHH
KDEQLVERSERLGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILC
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCEE
KDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVFKN
ECCCCEEEEECCCEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA