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The map label for this gene is serB [H]

Identifier: 147674858

GI number: 147674858

Start: 2055035

End: 2056021

Strand: Reverse

Name: serB [H]

Synonym: VC0395_A1924

Alternate gene names: 147674858

Gene position: 2056021-2055035 (Counterclockwise)

Preceding gene: 147673694

Following gene: 147673564

Centisome position: 67.99

GC content: 49.65

Gene sequence:

>987_bases
GTGGACATGGATGCTTTAACAACTTTACCGATCAAAAAACACACAACGCTACTCAATCGTTTTCCTGAAACGCGTTTTGT
CACCCAATTAGCGAAAAAACGTGCCAGTTGGATTGTGTTTGGACATTACCTAACTCCCGCTCAATTTGAAGACATGGATT
TCTTCACCAATCGCTTCAATGCCATCTTAGATATGTGGAAAGTGGGACGTTATGAAGTCGCATTGATGGACGGTGAGCTG
ACGTCTGAGCATGAAACCATTCTTAAAGCGCTAGAACTCGATTACGCGCGGATTCAGGATGTGCCCGATCTCACCAAGCC
GGGGTTAATTGTGCTGGATATGGACTCGACCGCGATCCAGATCGAATGCATTGATGAAATTGCTAAGCTTGCGGGAGTCG
GGGAAGAGGTCGCTGAAGTCACTGAGCGCGCGATGCAAGGTGAGCTGGATTTTGAGCAGAGTTTACGTTTGCGAGTCAGT
AAACTTAAAGATGCTCCGGAGCAGATCCTAAGCCAAGTACGCGAAACCCTGCCGTTAATGCCTGAATTACCCGAGCTGGT
GGCAACGCTGCATGCCTTTGGTTGGAAAGTCGCGATCGCCTCGGGCGGCTTTACCTACTTCTCTGATTATCTCAAAGAGC
AGTTGTCGCTAGACTATGCACAGTCTAACACTCTAGAAATTGTGAGCGGCAAACTGACTGGACAGGTGCTGGGAGAGGTA
GTCTCCGCGCAAACCAAAGCGGATATTTTGCTGACGCTTGCTCAGCAATACGATGTGGAAATTCATAACACGGTAGCGGT
TGGCGATGGCGCAAATGATTTGGTGATGATGGCGGCCGCAGGGCTTGGGGTGGCATACCATGCCAAACCTAAGGTTGAAG
CCAAGGCGCAAACGGCGGTGCGTTTTGCAGGATTAGGTGGCGTCGTGTGTATCCTTTCTGCCGCACTGGTCGCTCAGCAA
AAACTGAGTTGGAAAAGTAAGCCTTAG

Upstream 100 bases:

>100_bases
CCATGATGAGAGAAACCTACAAAAAACCAACTGCGCTCATATTGAGACTTGCGTTTTTAAATTGCAATAGGGTAACGTCT
GGCTATACCGAATAAGGAAA

Downstream 100 bases:

>100_bases
CCGACACATGGAACTTAGGTTAATCAAATAAGCCACGTTCAGTGACGTGGCTTATGTTTGGAAGAGATATCCCCTTCCTA
CTTGAAGCTGCAGGAGTGTT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MDMDALTTLPIKKHTTLLNRFPETRFVTQLAKKRASWIVFGHYLTPAQFEDMDFFTNRFNAILDMWKVGRYEVALMDGEL
TSEHETILKALELDYARIQDVPDLTKPGLIVLDMDSTAIQIECIDEIAKLAGVGEEVAEVTERAMQGELDFEQSLRLRVS
KLKDAPEQILSQVRETLPLMPELPELVATLHAFGWKVAIASGGFTYFSDYLKEQLSLDYAQSNTLEIVSGKLTGQVLGEV
VSAQTKADILLTLAQQYDVEIHNTVAVGDGANDLVMMAAAGLGVAYHAKPKVEAKAQTAVRFAGLGGVVCILSAALVAQQ
KLSWKSKP

Sequences:

>Translated_328_residues
MDMDALTTLPIKKHTTLLNRFPETRFVTQLAKKRASWIVFGHYLTPAQFEDMDFFTNRFNAILDMWKVGRYEVALMDGEL
TSEHETILKALELDYARIQDVPDLTKPGLIVLDMDSTAIQIECIDEIAKLAGVGEEVAEVTERAMQGELDFEQSLRLRVS
KLKDAPEQILSQVRETLPLMPELPELVATLHAFGWKVAIASGGFTYFSDYLKEQLSLDYAQSNTLEIVSGKLTGQVLGEV
VSAQTKADILLTLAQQYDVEIHNTVAVGDGANDLVMMAAAGLGVAYHAKPKVEAKAQTAVRFAGLGGVVCILSAALVAQQ
KLSWKSKP
>Mature_328_residues
MDMDALTTLPIKKHTTLLNRFPETRFVTQLAKKRASWIVFGHYLTPAQFEDMDFFTNRFNAILDMWKVGRYEVALMDGEL
TSEHETILKALELDYARIQDVPDLTKPGLIVLDMDSTAIQIECIDEIAKLAGVGEEVAEVTERAMQGELDFEQSLRLRVS
KLKDAPEQILSQVRETLPLMPELPELVATLHAFGWKVAIASGGFTYFSDYLKEQLSLDYAQSNTLEIVSGKLTGQVLGEV
VSAQTKADILLTLAQQYDVEIHNTVAVGDGANDLVMMAAAGLGVAYHAKPKVEAKAQTAVRFAGLGGVVCILSAALVAQQ
KLSWKSKP

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=173, Percent_Identity=28.9017341040462, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1790849, Length=283, Percent_Identity=54.0636042402827, Blast_Score=298, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI115534454, Length=238, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534456, Length=238, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534458, Length=240, Percent_Identity=32.0833333333333, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=43.6893203883495, Blast_Score=169, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24661601, Length=217, Percent_Identity=27.6497695852535, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 36146; Mature: 36146

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMDALTTLPIKKHTTLLNRFPETRFVTQLAKKRASWIVFGHYLTPAQFEDMDFFTNRFN
CCCCHHEECCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
AILDMWKVGRYEVALMDGELTSEHETILKALELDYARIQDVPDLTKPGLIVLDMDSTAIQ
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEE
IECIDEIAKLAGVGEEVAEVTERAMQGELDFEQSLRLRVSKLKDAPEQILSQVRETLPLM
EHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
PELPELVATLHAFGWKVAIASGGFTYFSDYLKEQLSLDYAQSNTLEIVSGKLTGQVLGEV
CCHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHCCHHCCCCCEEEEECHHHHHHHHHH
VSAQTKADILLTLAQQYDVEIHNTVAVGDGANDLVMMAAAGLGVAYHAKPKVEAKAQTAV
HHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHH
RFAGLGGVVCILSAALVAQQKLSWKSKP
HHHCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDMDALTTLPIKKHTTLLNRFPETRFVTQLAKKRASWIVFGHYLTPAQFEDMDFFTNRFN
CCCCHHEECCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
AILDMWKVGRYEVALMDGELTSEHETILKALELDYARIQDVPDLTKPGLIVLDMDSTAIQ
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEE
IECIDEIAKLAGVGEEVAEVTERAMQGELDFEQSLRLRVSKLKDAPEQILSQVRETLPLM
EHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
PELPELVATLHAFGWKVAIASGGFTYFSDYLKEQLSLDYAQSNTLEIVSGKLTGQVLGEV
CCHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHCCHHCCCCCEEEEECHHHHHHHHHH
VSAQTKADILLTLAQQYDVEIHNTVAVGDGANDLVMMAAAGLGVAYHAKPKVEAKAQTAV
HHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHH
RFAGLGGVVCILSAALVAQQKLSWKSKP
HHHCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]