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The map label for this gene is murA [H]

Identifier: 146343410

GI number: 146343410

Start: 6891217

End: 6892506

Strand: Reverse

Name: murA [H]

Synonym: BRADO6639

Alternate gene names: 146343410

Gene position: 6892506-6891217 (Counterclockwise)

Preceding gene: 146343411

Following gene: 146343409

Centisome position: 92.44

GC content: 68.29

Gene sequence:

>1290_bases
ATGGATCGCATTCGCATCGTCGGCGGCAACCCGCTTCACGGCACCATTCCGATTTCGGGCGCGAAGAACGCCGCTTTGCC
GCTGATGATCGCGGGCCTGCTGACACCGGAGACGCTGATCCTGGACAACGTCCCCCGCCTCGCCGACGTCGCGCAGCTGC
AGCGCATTCTCGGCAATCACGGCGTGGACATCATGTCCGTCGGCAAGCGCCCCGGCGATGGCCAGTACCAGGGCCAGACC
TTGCAGATCTCGGCGGCCAGCATCATCGACACCACCGCGCCTTATGAGCTGGTGTCGCGGATGCGCGCCAGCTTCTGGGT
GATCGCGCCGCTGCTCGCGCGCATGCACGAGGCGCGGGTGTCGCTGCCCGGCGGCTGCGCTATCGGCACGCGGCCGGTGG
ATCTCCTGATCATGGCGCTCACGAGGCTCGGCGCCAGCATCGACATTGACGCCGGCTACGTCGTCGCCAAGGCGCCAGGC
GGCCTGCGCGGCGGCACGATCGATTTCCCCAAGGTCACCGTCGGCGGCACCCATGTTGCGGTCATGGCAGCGAGCCTCGC
CAAGGGTACGACGGTCGTCACCAATGCCGCGTGCGAGCCGGAGATCTCCGATCTCGCCGACTGCTTGAACAAGATGGGCG
CACGCATCTCCGGCGCCGGTACGCCTGTTATCGAGATCGAGGGCGTGGCCTCGCTGCATGGCGCGCGGCACACGGTGCTG
CCGGATCGCATCGAGGCCGGCACCTACGCGATCGCCACCGCCATGACCGGCGGCGACGTCCAGCTTGCCGGCGCGCGGCC
GGAGCTGCTGCAGTCCGCGCTCGACGTGCTGGCCGAGGCTGGCGCGGAGATCTCCAGCGATGCGGAGGGTATTCGCGTGG
TGCGCAATGGCCACGGCATCCGCCCGGTGCAGGTCACCACCGCGCCGTTTCCCGGCTTCCCGACCGATCTCCAGGCGCAG
CTGATGGCGCTGATGGTGCGGGCGCAGGGCGCCTCGGCGATCACCGAGACCATCTTTGAAAACCGTTTCATGCACGTCCA
GGAACTCGCCCGCTTCGGCGCGCGTATCAGTCTGGACGGCGAGACCGCGCGGATCGAGGGCATCTCGACCCTGCGCGGCG
CGCCTGTGATGGCGACCGACCTGCGCGCCTCGGTGTCGCTGGTGATTGCGGGGCTGGCGGCGGAAGGCGAGACCATGATC
AATCGCGTCTACCATCTCGATCGCGGCTTCGAGCGGCTGGAGGACAAGCTGAAGGCCTGCGGCGCGACGATCGAGCGCAT
TCGCGAATGA

Upstream 100 bases:

>100_bases
GAGGATGCGACCTGCCGTTGCGAACCCATCAAATCGCCGTAATGTCGGTCCTGTTGCGCCAACCTTAGGCAAATCTCCCG
GCCAGCTCGATAGGACCAGC

Downstream 100 bases:

>100_bases
GATGAGGATGATGTCGTGACCGACCGGCTCAAACTGATCGCGCTCGACGCCGACGATCTCGCCGTGATTTCCGCCCACGT
CCAAGATGCGCGGGTGCAGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDRIRIVGGNPLHGTIPISGAKNAALPLMIAGLLTPETLILDNVPRLADVAQLQRILGNHGVDIMSVGKRPGDGQYQGQT
LQISAASIIDTTAPYELVSRMRASFWVIAPLLARMHEARVSLPGGCAIGTRPVDLLIMALTRLGASIDIDAGYVVAKAPG
GLRGGTIDFPKVTVGGTHVAVMAASLAKGTTVVTNAACEPEISDLADCLNKMGARISGAGTPVIEIEGVASLHGARHTVL
PDRIEAGTYAIATAMTGGDVQLAGARPELLQSALDVLAEAGAEISSDAEGIRVVRNGHGIRPVQVTTAPFPGFPTDLQAQ
LMALMVRAQGASAITETIFENRFMHVQELARFGARISLDGETARIEGISTLRGAPVMATDLRASVSLVIAGLAAEGETMI
NRVYHLDRGFERLEDKLKACGATIERIRE

Sequences:

>Translated_429_residues
MDRIRIVGGNPLHGTIPISGAKNAALPLMIAGLLTPETLILDNVPRLADVAQLQRILGNHGVDIMSVGKRPGDGQYQGQT
LQISAASIIDTTAPYELVSRMRASFWVIAPLLARMHEARVSLPGGCAIGTRPVDLLIMALTRLGASIDIDAGYVVAKAPG
GLRGGTIDFPKVTVGGTHVAVMAASLAKGTTVVTNAACEPEISDLADCLNKMGARISGAGTPVIEIEGVASLHGARHTVL
PDRIEAGTYAIATAMTGGDVQLAGARPELLQSALDVLAEAGAEISSDAEGIRVVRNGHGIRPVQVTTAPFPGFPTDLQAQ
LMALMVRAQGASAITETIFENRFMHVQELARFGARISLDGETARIEGISTLRGAPVMATDLRASVSLVIAGLAAEGETMI
NRVYHLDRGFERLEDKLKACGATIERIRE
>Mature_429_residues
MDRIRIVGGNPLHGTIPISGAKNAALPLMIAGLLTPETLILDNVPRLADVAQLQRILGNHGVDIMSVGKRPGDGQYQGQT
LQISAASIIDTTAPYELVSRMRASFWVIAPLLARMHEARVSLPGGCAIGTRPVDLLIMALTRLGASIDIDAGYVVAKAPG
GLRGGTIDFPKVTVGGTHVAVMAASLAKGTTVVTNAACEPEISDLADCLNKMGARISGAGTPVIEIEGVASLHGARHTVL
PDRIEAGTYAIATAMTGGDVQLAGARPELLQSALDVLAEAGAEISSDAEGIRVVRNGHGIRPVQVTTAPFPGFPTDLQAQ
LMALMVRAQGASAITETIFENRFMHVQELARFGARISLDGETARIEGISTLRGAPVMATDLRASVSLVIAGLAAEGETMI
NRVYHLDRGFERLEDKLKACGATIERIRE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=430, Percent_Identity=48.6046511627907, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44974; Mature: 44974

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGNPLHGTIPISGAKNAALPLMIAGLLTPETLILDNVPRLADVAQLQRILGNH
CCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHCCC
GVDIMSVGKRPGDGQYQGQTLQISAASIIDTTAPYELVSRMRASFWVIAPLLARMHEARV
CCEEEECCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLPGGCAIGTRPVDLLIMALTRLGASIDIDAGYVVAKAPGGLRGGTIDFPKVTVGGTHVA
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCEEEECCCHHH
VMAASLAKGTTVVTNAACEPEISDLADCLNKMGARISGAGTPVIEIEGVASLHGARHTVL
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCEECCCCCCEEEECCHHHHCCCCCCCC
PDRIEAGTYAIATAMTGGDVQLAGARPELLQSALDVLAEAGAEISSDAEGIRVVRNGHGI
CCHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
RPVQVTTAPFPGFPTDLQAQLMALMVRAQGASAITETIFENRFMHVQELARFGARISLDG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
ETARIEGISTLRGAPVMATDLRASVSLVIAGLAAEGETMINRVYHLDRGFERLEDKLKAC
CCEEECCHHHHCCCCEEEHHHHHHEEHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GATIERIRE
HHHHHHHCC
>Mature Secondary Structure
MDRIRIVGGNPLHGTIPISGAKNAALPLMIAGLLTPETLILDNVPRLADVAQLQRILGNH
CCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHCCC
GVDIMSVGKRPGDGQYQGQTLQISAASIIDTTAPYELVSRMRASFWVIAPLLARMHEARV
CCEEEECCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLPGGCAIGTRPVDLLIMALTRLGASIDIDAGYVVAKAPGGLRGGTIDFPKVTVGGTHVA
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCEEEECCCHHH
VMAASLAKGTTVVTNAACEPEISDLADCLNKMGARISGAGTPVIEIEGVASLHGARHTVL
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCEECCCCCCEEEECCHHHHCCCCCCCC
PDRIEAGTYAIATAMTGGDVQLAGARPELLQSALDVLAEAGAEISSDAEGIRVVRNGHGI
CCHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
RPVQVTTAPFPGFPTDLQAQLMALMVRAQGASAITETIFENRFMHVQELARFGARISLDG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
ETARIEGISTLRGAPVMATDLRASVSLVIAGLAAEGETMINRVYHLDRGFERLEDKLKAC
CCEEECCHHHHCCCCEEEHHHHHHEEHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GATIERIRE
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA