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The map label for this gene is tynA [H]

Identifier: 146343302

GI number: 146343302

Start: 6776651

End: 6778654

Strand: Reverse

Name: tynA [H]

Synonym: BRADO6525

Alternate gene names: 146343302

Gene position: 6778654-6776651 (Counterclockwise)

Preceding gene: 146343303

Following gene: 146343299

Centisome position: 90.91

GC content: 65.72

Gene sequence:

>2004_bases
ATGGAGTCCAACGTGCAGGACATCACCGCCGCCGCGACCGCCGTGGTTCATCCGCTCGACCCTTTGACATCGGACGAGAT
CGCGGCCGCCTGCCGCCCGGTGCATGCGGCCGCCGTCTCCGCGGAGCACTGCCGCTTCCCGATCGTGCGGCTGGAGGAGC
CAGCCAAGGCCGAGCTGATCGCCTGCGAGCGCGGACAGGCGCTGCCGCGCAGGGCCTTCGTGGTGTCGCTCGACATCGCG
AGCGGCGAGTCGGTCGAGCACGTCGTCGATCTCGGCCGCGGCGAGATCGTTGCCCGCAAGGTGGTGCCGAACCGCGAGGC
GCCTTACGGCCAGCCGCCGGTCATGCTCGAAGAGTTCTTCCGCTGTGAGGCCGCGGTCAAGGCCGATGCCGGCTGGCGCA
AGGCGATGCATCGGCGTGGTCTCACCGACAAGGACATCGAGCTGGTGCAGGTCGATCCATTCTCGTCCGGCTTCTTCGAC
CTGCCGTTCGAGCGCGGCGCCCGCATCGTCCGCGCCGTCAGCTATTTCCGCGAGCATCCGCAGGACAATGGCTATGCGCA
TCCGATCGAGGGTGTGGTCGCCGTGGTCGATCTGATCGCCGGCAAGGTGATCGATCTGACCGATCAGGATCCGGTCATCC
CGATCCCGCGCAAGAAGCGCAACTACGGTGCGCATGAGGTGACCTCGCCGCGTACCGGCATCAAGCCGCTCGACATCGAG
CAGCCGCAGGGGCCGAGCTTCACGGTCGACGGCTGGAAGGTCGATTGGCAGAAATGGAGTTTTCGCGTCGGCTTCACGCC
GCGCGAGGGCCTCGTGCTGCATCGGCTGTGCTATCAGGACGGCGAGCGCACCCGCCCGATCATCCATCGCGCCAGCGTCA
CCGAGATGGTCGTGCCTTACGCCGACCCGACCGCCAACCATTTCTGGAAGTCGGCGTTCGACGCCGGCGAATACGGCCTC
GGCATGCTGGCGAATGCGCTGGAGCTCGGCTGCGACTGTCTCGGCAACATCCATTACTTCGACGTGCCCGCCGCCGACAG
CAAGGGCGAGCCGTTCGTGATGCAGAACGCGATCTGCATGCACGAGGAGGACTACGGCGTCCTCTGGAAGCACTATGAGT
TCCGCAACGGCCTGTTCGAGGTGCGGCGCTCGCGCCGCCTCGTCATCAGCTTCTTCGCCACCGTCGGCAACTACGATTAC
GGCTTCTACTGGTATCTGTACCAGGACGGCACCATCCAGCTCGAATGCAAGCTGACCGGCATCATCCAGACCGCGGCGGT
GGCGCCGGGGGCGACCTATCCGTGGGGCGGCATGGTCGACGACAATCTCGGTGGGCCCACGCATCAGCATTTCTTCAACG
CTCGCCTGCACATGGACATCGATGGCGGCGGCAACACCGTCACCGAGCACGAGTTCGTGCCGCGGCCCTGGGGCGGCGAC
AATCCGCACGGCAACGTGTTCGACACCACGAGCCGGGTGCTGGCGCGCGAGCGCGATGCGGCCCGCCTCGCCAATGGCGA
GACCGGACGCTACTGGAAGATCTCCAATCCCAACGCAAAGAACTCAGTGGGTGGCGCGCCGGGCTACAAGCTGATCGTCA
ATCCCAGTCCGGTGATGCTGGCGCAGGAGGGGAGCTTCGTGCGCAGCCGCGGCGGCTTCGCCACCAAGCATGTCTGGGTC
ACCGCCTATGATCCGGCGGAGAAATACGCCAGCGGCGACTATCCGAACGTGCATGGCGGCGGCGACGGTCTGCCGCGCTA
CATCGCGCAGAACCGCAGCATCGAAAACACCGACATCGTGGTCTGGCATTCGTTCGGGCACACTCATGTGTGCAAACCGG
AGGATTTCCCGATCATGCCGGTCGAGTATGCCGGCTTCTTGCTGAAGCCCGTCGGCTTCTTCGCCGCGAATGCCGGCTTC
GACATTCCAGCGGAGCGGAACGCGAAGAGCGTGCTGAGCGCGGACGGGACGTCCGGCACGGAAGGCGGTAGCTGCTGTCA
CTGA

Upstream 100 bases:

>100_bases
TCAAGCTCGCCACCCAGGGCAAGGCGATGGACATCGCCCAGGACCATCGCTGGCTCGCCGGCTTCCGCGCCATCACCGCG
CATCTCTCCTAATCGAACCG

Downstream 100 bases:

>100_bases
GCGCGGTCAACGCATGGCGGAGGAGAGATGCATGCCGGGAACAGGTTAGGCGTCAGCGCGCACCAATACGTTGATGTCGC
AGCCAGAAACCGGCAAAATC

Product: tyramine oxidase

Products: NA

Alternate protein names: Copper amine oxidase; MAOXI [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MESNVQDITAAATAVVHPLDPLTSDEIAAACRPVHAAAVSAEHCRFPIVRLEEPAKAELIACERGQALPRRAFVVSLDIA
SGESVEHVVDLGRGEIVARKVVPNREAPYGQPPVMLEEFFRCEAAVKADAGWRKAMHRRGLTDKDIELVQVDPFSSGFFD
LPFERGARIVRAVSYFREHPQDNGYAHPIEGVVAVVDLIAGKVIDLTDQDPVIPIPRKKRNYGAHEVTSPRTGIKPLDIE
QPQGPSFTVDGWKVDWQKWSFRVGFTPREGLVLHRLCYQDGERTRPIIHRASVTEMVVPYADPTANHFWKSAFDAGEYGL
GMLANALELGCDCLGNIHYFDVPAADSKGEPFVMQNAICMHEEDYGVLWKHYEFRNGLFEVRRSRRLVISFFATVGNYDY
GFYWYLYQDGTIQLECKLTGIIQTAAVAPGATYPWGGMVDDNLGGPTHQHFFNARLHMDIDGGGNTVTEHEFVPRPWGGD
NPHGNVFDTTSRVLARERDAARLANGETGRYWKISNPNAKNSVGGAPGYKLIVNPSPVMLAQEGSFVRSRGGFATKHVWV
TAYDPAEKYASGDYPNVHGGGDGLPRYIAQNRSIENTDIVVWHSFGHTHVCKPEDFPIMPVEYAGFLLKPVGFFAANAGF
DIPAERNAKSVLSADGTSGTEGGSCCH

Sequences:

>Translated_667_residues
MESNVQDITAAATAVVHPLDPLTSDEIAAACRPVHAAAVSAEHCRFPIVRLEEPAKAELIACERGQALPRRAFVVSLDIA
SGESVEHVVDLGRGEIVARKVVPNREAPYGQPPVMLEEFFRCEAAVKADAGWRKAMHRRGLTDKDIELVQVDPFSSGFFD
LPFERGARIVRAVSYFREHPQDNGYAHPIEGVVAVVDLIAGKVIDLTDQDPVIPIPRKKRNYGAHEVTSPRTGIKPLDIE
QPQGPSFTVDGWKVDWQKWSFRVGFTPREGLVLHRLCYQDGERTRPIIHRASVTEMVVPYADPTANHFWKSAFDAGEYGL
GMLANALELGCDCLGNIHYFDVPAADSKGEPFVMQNAICMHEEDYGVLWKHYEFRNGLFEVRRSRRLVISFFATVGNYDY
GFYWYLYQDGTIQLECKLTGIIQTAAVAPGATYPWGGMVDDNLGGPTHQHFFNARLHMDIDGGGNTVTEHEFVPRPWGGD
NPHGNVFDTTSRVLARERDAARLANGETGRYWKISNPNAKNSVGGAPGYKLIVNPSPVMLAQEGSFVRSRGGFATKHVWV
TAYDPAEKYASGDYPNVHGGGDGLPRYIAQNRSIENTDIVVWHSFGHTHVCKPEDFPIMPVEYAGFLLKPVGFFAANAGF
DIPAERNAKSVLSADGTSGTEGGSCCH
>Mature_667_residues
MESNVQDITAAATAVVHPLDPLTSDEIAAACRPVHAAAVSAEHCRFPIVRLEEPAKAELIACERGQALPRRAFVVSLDIA
SGESVEHVVDLGRGEIVARKVVPNREAPYGQPPVMLEEFFRCEAAVKADAGWRKAMHRRGLTDKDIELVQVDPFSSGFFD
LPFERGARIVRAVSYFREHPQDNGYAHPIEGVVAVVDLIAGKVIDLTDQDPVIPIPRKKRNYGAHEVTSPRTGIKPLDIE
QPQGPSFTVDGWKVDWQKWSFRVGFTPREGLVLHRLCYQDGERTRPIIHRASVTEMVVPYADPTANHFWKSAFDAGEYGL
GMLANALELGCDCLGNIHYFDVPAADSKGEPFVMQNAICMHEEDYGVLWKHYEFRNGLFEVRRSRRLVISFFATVGNYDY
GFYWYLYQDGTIQLECKLTGIIQTAAVAPGATYPWGGMVDDNLGGPTHQHFFNARLHMDIDGGGNTVTEHEFVPRPWGGD
NPHGNVFDTTSRVLARERDAARLANGETGRYWKISNPNAKNSVGGAPGYKLIVNPSPVMLAQEGSFVRSRGGFATKHVWV
TAYDPAEKYASGDYPNVHGGGDGLPRYIAQNRSIENTDIVVWHSFGHTHVCKPEDFPIMPVEYAGFLLKPVGFFAANAGF
DIPAERNAKSVLSADGTSGTEGGSCCH

Specific function: The exact function of maoXI is not known [H]

COG id: COG3733

COG function: function code Q; Cu2+-containing amine oxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the copper/topaquinone oxidase family [H]

Homologues:

Organism=Homo sapiens, GI73486661, Length=471, Percent_Identity=26.7515923566879, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI60498982, Length=409, Percent_Identity=27.3838630806846, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI60498984, Length=414, Percent_Identity=27.536231884058, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI4502119, Length=413, Percent_Identity=25.90799031477, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1787651, Length=637, Percent_Identity=32.0251177394035, Blast_Score=329, Evalue=4e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000269
- InterPro:   IPR015798
- InterPro:   IPR016182
- InterPro:   IPR015800
- InterPro:   IPR015801
- InterPro:   IPR015802 [H]

Pfam domain/function: PF01179 Cu_amine_oxid; PF02727 Cu_amine_oxidN2; PF02728 Cu_amine_oxidN3 [H]

EC number: =1.4.3.21 [H]

Molecular weight: Translated: 73595; Mature: 73595

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS01164 COPPER_AMINE_OXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESNVQDITAAATAVVHPLDPLTSDEIAAACRPVHAAAVSAEHCRFPIVRLEEPAKAELI
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHCCHHHCCCCEEEECCCCCCEEE
ACERGQALPRRAFVVSLDIASGESVEHVVDLGRGEIVARKVVPNREAPYGQPPVMLEEFF
EECCCCCCCCEEEEEEEECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
RCEAAVKADAGWRKAMHRRGLTDKDIELVQVDPFSSGFFDLPFERGARIVRAVSYFREHP
HHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHCC
QDNGYAHPIEGVVAVVDLIAGKVIDLTDQDPVIPIPRKKRNYGAHEVTSPRTGIKPLDIE
CCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QPQGPSFTVDGWKVDWQKWSFRVGFTPREGLVLHRLCYQDGERTRPIIHRASVTEMVVPY
CCCCCCEEECCEEEECEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEECCHHEEEEEC
ADPTANHFWKSAFDAGEYGLGMLANALELGCDCLGNIHYFDVPAADSKGEPFVMQNAICM
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEECEEEE
HEEDYGVLWKHYEFRNGLFEVRRSRRLVISFFATVGNYDYGFYWYLYQDGTIQLECKLTG
ECCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCEEEEEEEECCEEEEEEEEEE
IIQTAAVAPGATYPWGGMVDDNLGGPTHQHFFNARLHMDIDGGGNTVTEHEFVPRPWGGD
EEEEHHCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCC
NPHGNVFDTTSRVLARERDAARLANGETGRYWKISNPNAKNSVGGAPGYKLIVNPSPVML
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCEEE
AQEGSFVRSRGGFATKHVWVTAYDPAEKYASGDYPNVHGGGDGLPRYIAQNRSIENTDIV
ECCCCEEECCCCEEEEEEEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEE
VWHSFGHTHVCKPEDFPIMPVEYAGFLLKPVGFFAANAGFDIPAERNAKSVLSADGTSGT
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCCCCCCCC
EGGSCCH
CCCCCCC
>Mature Secondary Structure
MESNVQDITAAATAVVHPLDPLTSDEIAAACRPVHAAAVSAEHCRFPIVRLEEPAKAELI
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHCCHHHCCCCEEEECCCCCCEEE
ACERGQALPRRAFVVSLDIASGESVEHVVDLGRGEIVARKVVPNREAPYGQPPVMLEEFF
EECCCCCCCCEEEEEEEECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
RCEAAVKADAGWRKAMHRRGLTDKDIELVQVDPFSSGFFDLPFERGARIVRAVSYFREHP
HHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHCC
QDNGYAHPIEGVVAVVDLIAGKVIDLTDQDPVIPIPRKKRNYGAHEVTSPRTGIKPLDIE
CCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QPQGPSFTVDGWKVDWQKWSFRVGFTPREGLVLHRLCYQDGERTRPIIHRASVTEMVVPY
CCCCCCEEECCEEEECEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEECCHHEEEEEC
ADPTANHFWKSAFDAGEYGLGMLANALELGCDCLGNIHYFDVPAADSKGEPFVMQNAICM
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEECEEEE
HEEDYGVLWKHYEFRNGLFEVRRSRRLVISFFATVGNYDYGFYWYLYQDGTIQLECKLTG
ECCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCEEEEEEEECCEEEEEEEEEE
IIQTAAVAPGATYPWGGMVDDNLGGPTHQHFFNARLHMDIDGGGNTVTEHEFVPRPWGGD
EEEEHHCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCC
NPHGNVFDTTSRVLARERDAARLANGETGRYWKISNPNAKNSVGGAPGYKLIVNPSPVML
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCEEE
AQEGSFVRSRGGFATKHVWVTAYDPAEKYASGDYPNVHGGGDGLPRYIAQNRSIENTDIV
ECCCCEEECCCCEEEEEEEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEE
VWHSFGHTHVCKPEDFPIMPVEYAGFLLKPVGFFAANAGFDIPAERNAKSVLSADGTSGT
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCCCCCCCC
EGGSCCH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8366046 [H]