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The map label for this gene is dhmA1 [H]

Identifier: 146343299

GI number: 146343299

Start: 6773272

End: 6774195

Strand: Reverse

Name: dhmA1 [H]

Synonym: BRADO6522

Alternate gene names: 146343299

Gene position: 6774195-6773272 (Counterclockwise)

Preceding gene: 146343302

Following gene: 146343297

Centisome position: 90.85

GC content: 67.75

Gene sequence:

>924_bases
GTGATCACGCGGGGCACGGCGACGACACTGGGCCCGCTGAAGCAGGTCACCGCCGGCGAGATCAGCATCGGCTACGCCGA
AGCAGGCCCCGCCGATGGTCCGGTCGTCATCCTGCTGCACGGCTGGCCCTACGACATCCACAGCTTCGCCGATGTCGCGC
CGGCGCTGGCCGCGTCGGGTCATCGCGTGATCATTCCCCATCTGCGCGGCTATGGCACGACGCGGCTGCTCTCACCCACC
GCGCTGCGCAGCGGCCAGCGGGTCGCGGTCGCCGCCGATATCGTCGCTTTGATGGATGCGCTCGGCATCGGGTCCGCCAC
GCTCGCCGGCTATGATTGGGGCGCGCGCACCGCCAACATCATCGCCGCGCTGTGGCCCGAGCGCTGCAAGGCGATGGTCT
CGGTCAGCGGCTATCTGATCGGCAGCCAGCAGGCCGGGCTCAAGCCGCTGCCACCGGCCGCCGAGCTGCAATGGTGGTAT
CAATTTTACTTCGCCACCGAGCGTGGGCGAGAGGGCTACGACACGAACCGGAAGGATTTCGCGCGATTGATCTGGCAGAC
GGCCTCGCCGAAATGGGCGTTCGACGATGCGACCTTCGGGCGCAGCGCGGCCGCCTTCGACAACCCCGATCACGTCGATG
TCGTCGTGCATAATTATCGCTGGCGGCTCGGCCTCGTGCAGGGCGAGGCCAGATATGACGAGCTCGAGGCGAAGCTCGCG
ACCTTCCCGAACATCACCGTGCCGACCATCACGATGGAGGGAGACGCCAACGGCGCGCCGCATCCGCCGCCGGCGGCCTA
CGCGAAGAAGTTCACCGGCCGCTACGAGCATCGCCTGATCACGGGCGGCATCGGTCACAATCTGCCGCAGGAGGCGCCGC
AGGCATTCACACAGGCCGTGATCGACGTCATGGCGGGCGCCTGA

Upstream 100 bases:

>100_bases
CCGCCGCAACTTTCTCGCGATGGCTGGAACCGCAGTCGGGGCGTTCCAGCTCGGTTCCCGTTCCCGAGCGCAGGGTTTCA
ATGCGTCAGCAAAGTTGCCG

Downstream 100 bases:

>100_bases
CACGCGCGCCATGGATCGGCCGCAGGCGGGATCATCACCGCCTGCGCTGCAGCCACGTCTCCCGCCGCACCACCCACTGC
TCGGAGCGCGCCTCGCCATT

Product: alpha/beta family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MITRGTATTLGPLKQVTAGEISIGYAEAGPADGPVVILLHGWPYDIHSFADVAPALAASGHRVIIPHLRGYGTTRLLSPT
ALRSGQRVAVAADIVALMDALGIGSATLAGYDWGARTANIIAALWPERCKAMVSVSGYLIGSQQAGLKPLPPAAELQWWY
QFYFATERGREGYDTNRKDFARLIWQTASPKWAFDDATFGRSAAAFDNPDHVDVVVHNYRWRLGLVQGEARYDELEAKLA
TFPNITVPTITMEGDANGAPHPPPAAYAKKFTGRYEHRLITGGIGHNLPQEAPQAFTQAVIDVMAGA

Sequences:

>Translated_307_residues
MITRGTATTLGPLKQVTAGEISIGYAEAGPADGPVVILLHGWPYDIHSFADVAPALAASGHRVIIPHLRGYGTTRLLSPT
ALRSGQRVAVAADIVALMDALGIGSATLAGYDWGARTANIIAALWPERCKAMVSVSGYLIGSQQAGLKPLPPAAELQWWY
QFYFATERGREGYDTNRKDFARLIWQTASPKWAFDDATFGRSAAAFDNPDHVDVVVHNYRWRLGLVQGEARYDELEAKLA
TFPNITVPTITMEGDANGAPHPPPAAYAKKFTGRYEHRLITGGIGHNLPQEAPQAFTQAVIDVMAGA
>Mature_307_residues
MITRGTATTLGPLKQVTAGEISIGYAEAGPADGPVVILLHGWPYDIHSFADVAPALAASGHRVIIPHLRGYGTTRLLSPT
ALRSGQRVAVAADIVALMDALGIGSATLAGYDWGARTANIIAALWPERCKAMVSVSGYLIGSQQAGLKPLPPAAELQWWY
QFYFATERGREGYDTNRKDFARLIWQTASPKWAFDDATFGRSAAAFDNPDHVDVVVHNYRWRLGLVQGEARYDELEAKLA
TFPNITVPTITMEGDANGAPHPPPAAYAKKFTGRYEHRLITGGIGHNLPQEAPQAFTQAVIDVMAGA

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=145, Percent_Identity=30.3448275862069, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33077; Mature: 33077

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRGTATTLGPLKQVTAGEISIGYAEAGPADGPVVILLHGWPYDIHSFADVAPALAASG
CCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
HRVIIPHLRGYGTTRLLSPTALRSGQRVAVAADIVALMDALGIGSATLAGYDWGARTANI
CEEEECCCCCCCCCEECCHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEECCCCCCHHHHH
IAALWPERCKAMVSVSGYLIGSQQAGLKPLPPAAELQWWYQFYFATERGREGYDTNRKDF
HHHHCHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHEEHHEEEECCCCCCCCCCCHHHH
ARLIWQTASPKWAFDDATFGRSAAAFDNPDHVDVVVHNYRWRLGLVQGEARYDELEAKLA
HHHHHHCCCCCEECCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEECCCHHHHHHHHHH
TFPNITVPTITMEGDANGAPHPPPAAYAKKFTGRYEHRLITGGIGHNLPQEAPQAFTQAV
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCHHEEEEECCCCCCCCHHHHHHHHHHH
IDVMAGA
HHHHHCC
>Mature Secondary Structure
MITRGTATTLGPLKQVTAGEISIGYAEAGPADGPVVILLHGWPYDIHSFADVAPALAASG
CCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
HRVIIPHLRGYGTTRLLSPTALRSGQRVAVAADIVALMDALGIGSATLAGYDWGARTANI
CEEEECCCCCCCCCEECCHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEECCCCCCHHHHH
IAALWPERCKAMVSVSGYLIGSQQAGLKPLPPAAELQWWYQFYFATERGREGYDTNRKDF
HHHHCHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHEEHHEEEECCCCCCCCCCCHHHH
ARLIWQTASPKWAFDDATFGRSAAAFDNPDHVDVVVHNYRWRLGLVQGEARYDELEAKLA
HHHHHHCCCCCEECCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEECCCHHHHHHHHHH
TFPNITVPTITMEGDANGAPHPPPAAYAKKFTGRYEHRLITGGIGHNLPQEAPQAFTQAV
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCHHEEEEECCCCCCCCHHHHHHHHHHH
IDVMAGA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]