| Definition | Bradyrhizobium sp. ORS278 chromosome, complete genome. |
|---|---|
| Accession | NC_009445 |
| Length | 7,456,587 |
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The map label for this gene is fabG [C]
Identifier: 146342970
GI number: 146342970
Start: 6378635
End: 6379483
Strand: Direct
Name: fabG [C]
Synonym: BRADO6153
Alternate gene names: 146342970
Gene position: 6378635-6379483 (Clockwise)
Preceding gene: 146342969
Following gene: 146342975
Centisome position: 85.54
GC content: 68.08
Gene sequence:
>849_bases GTGTCCCACCCTGCCTTGTCCCCCGATCAAACAGCCGTCGTCACCGGAGGCGCCTCCGGCATCGGCCTCGCCGCGGCGAA GCGCTTCGCCGCACGCGGCATGAATGTCTGCATCGCCGATGTCGATGACGCGCGCCTCCGCGAGGCCGCCACCCAAGTGA CGGCGGAAGCGACACGCGGCGGGGCCGCCATCATGACGGCGAAGGTCGACGTCGGCAGCCGCGACAGCGTGGCCGCGCTC GAAGAAGCCGTGCGCCAGCGGTTCGGCGCCGTCGATGTTTTGATGAACAATGCCGGCATCCAGCCGGGCAGCAGGATGTT CGGACCGGAGGAGACTTGGCAGCGCATTCTCGGTGTCAATCTGTGGGGCATCATCCATGGCTCGCAGGTGTTCGCCCCCG GCATGATCGCGCAAGGGCGGCCGGCGCTGATCATCAACACCGGCTCCAAGCAGGGCATCACCACGCCGCCCGGCGATCCC GCCTACAACGTCTCCAAGGCCGGCGTGAAGGCGTTCACCGAGGCGCTGCAGCACGAGCTGCGCAACACCAGGGATTGCCA GGTGACGGCGCATCTGTTCATTCCGGGCTTCGTGTTCACGCCGCTTACGGCAAACGGCCGCGTCGAGAAGCCGGCTGCCG CGTGGACGCCGGAGCAGACGGTGGACTTCATGCTGGAGCGCGTGCAGGCCGGCGACTTCTACGTACTGTGTCCGGACAAC GACGTGCCGCGCGCGCTCGACGAGCGGCGCATCCTTTGGGCCGCCGGCGACATCGTCGAGAACCGGCCGCCGCTTTCGCG CTGGCATGCGGACTACGCGGAGGCGTTCGCGGCGTTCGTGAAGCAGTGA
Upstream 100 bases:
>100_bases GCAGCCGCGAAGACCTGTCATGACCTGACGCGATGATCTTGCGGCCGCGCCAGAACGTCATAGACAAATGTCGTCATCAT CCTTGCCGGAGAGCCTGCCC
Downstream 100 bases:
>100_bases TCAGGACGTCTCGGGCGCCTGCACCAGCAGGCGCCTGACCAGCGCGAGCGCGGTCTCGGTGGCCGGGTCGGCCGCGATCA CAGACACCGCGAGCACGATG
Product: NAD(P)-dependent oxidoreductase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 282; Mature: 281
Protein sequence:
>282_residues MSHPALSPDQTAVVTGGASGIGLAAAKRFAARGMNVCIADVDDARLREAATQVTAEATRGGAAIMTAKVDVGSRDSVAAL EEAVRQRFGAVDVLMNNAGIQPGSRMFGPEETWQRILGVNLWGIIHGSQVFAPGMIAQGRPALIINTGSKQGITTPPGDP AYNVSKAGVKAFTEALQHELRNTRDCQVTAHLFIPGFVFTPLTANGRVEKPAAAWTPEQTVDFMLERVQAGDFYVLCPDN DVPRALDERRILWAAGDIVENRPPLSRWHADYAEAFAAFVKQ
Sequences:
>Translated_282_residues MSHPALSPDQTAVVTGGASGIGLAAAKRFAARGMNVCIADVDDARLREAATQVTAEATRGGAAIMTAKVDVGSRDSVAAL EEAVRQRFGAVDVLMNNAGIQPGSRMFGPEETWQRILGVNLWGIIHGSQVFAPGMIAQGRPALIINTGSKQGITTPPGDP AYNVSKAGVKAFTEALQHELRNTRDCQVTAHLFIPGFVFTPLTANGRVEKPAAAWTPEQTVDFMLERVQAGDFYVLCPDN DVPRALDERRILWAAGDIVENRPPLSRWHADYAEAFAAFVKQ >Mature_281_residues SHPALSPDQTAVVTGGASGIGLAAAKRFAARGMNVCIADVDDARLREAATQVTAEATRGGAAIMTAKVDVGSRDSVAALE EAVRQRFGAVDVLMNNAGIQPGSRMFGPEETWQRILGVNLWGIIHGSQVFAPGMIAQGRPALIINTGSKQGITTPPGDPA YNVSKAGVKAFTEALQHELRNTRDCQVTAHLFIPGFVFTPLTANGRVEKPAAAWTPEQTVDFMLERVQAGDFYVLCPDND VPRALDERRILWAAGDIVENRPPLSRWHADYAEAFAAFVKQ
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI25282469, Length=240, Percent_Identity=27.5, Blast_Score=82, Evalue=8e-16, Organism=Homo sapiens, GI4758504, Length=231, Percent_Identity=29.004329004329, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=28.921568627451, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI83715985, Length=183, Percent_Identity=31.6939890710383, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI15277342, Length=230, Percent_Identity=30, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI142976729, Length=250, Percent_Identity=24.4, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=30.1507537688442, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI32483357, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=26.4550264550265, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=29.6703296703297, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=31.7948717948718, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI87082100, Length=222, Percent_Identity=25.6756756756757, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1788459, Length=195, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789208, Length=223, Percent_Identity=28.2511210762332, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1790717, Length=214, Percent_Identity=27.1028037383178, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787820, Length=173, Percent_Identity=26.5895953757225, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1789057, Length=223, Percent_Identity=26.9058295964126, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI87082160, Length=202, Percent_Identity=30.6930693069307, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787905, Length=131, Percent_Identity=31.2977099236641, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI25147288, Length=201, Percent_Identity=35.8208955223881, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17555706, Length=199, Percent_Identity=35.678391959799, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17567345, Length=213, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203117, Length=229, Percent_Identity=26.6375545851528, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17564282, Length=204, Percent_Identity=25.9803921568627, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193203115, Length=229, Percent_Identity=26.6375545851528, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561402, Length=196, Percent_Identity=27.5510204081633, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI71994600, Length=218, Percent_Identity=26.605504587156, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI71994604, Length=170, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=30.1507537688442, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=179, Percent_Identity=31.8435754189944, Blast_Score=63, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6320089, Length=218, Percent_Identity=26.1467889908257, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI21357041, Length=207, Percent_Identity=31.8840579710145, Blast_Score=86, Evalue=4e-17, Organism=Drosophila melanogaster, GI221331218, Length=172, Percent_Identity=35.4651162790698, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24665243, Length=172, Percent_Identity=35.4651162790698, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI221331216, Length=173, Percent_Identity=35.2601156069364, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24665247, Length=173, Percent_Identity=35.2601156069364, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI28571526, Length=215, Percent_Identity=30.2325581395349, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=29.2929292929293, Blast_Score=78, Evalue=9e-15, Organism=Drosophila melanogaster, GI24649181, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI17737361, Length=210, Percent_Identity=29.0476190476191, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=28.6995515695067, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI116007234, Length=208, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21355631, Length=178, Percent_Identity=29.2134831460674, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24640442, Length=223, Percent_Identity=28.6995515695067, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007232, Length=183, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24639444, Length=198, Percent_Identity=30.8080808080808, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24656154, Length=215, Percent_Identity=28.8372093023256, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI19922628, Length=215, Percent_Identity=28.8372093023256, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584752, Length=199, Percent_Identity=28.1407035175879, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI23397609, Length=200, Percent_Identity=30, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI28571387, Length=201, Percent_Identity=28.8557213930348, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24641232, Length=180, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 30206; Mature: 30074
Theoretical pI: Translated: 6.36; Mature: 6.36
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSHPALSPDQTAVVTGGASGIGLAAAKRFAARGMNVCIADVDDARLREAATQVTAEATRG CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCC GAAIMTAKVDVGSRDSVAALEEAVRQRFGAVDVLMNNAGIQPGSRMFGPEETWQRILGVN CEEEEEEEECCCCCCHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCCHHHHHHHHHCCC LWGIIHGSQVFAPGMIAQGRPALIINTGSKQGITTPPGDPAYNVSKAGVKAFTEALQHEL EEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH RNTRDCQVTAHLFIPGFVFTPLTANGRVEKPAAAWTPEQTVDFMLERVQAGDFYVLCPDN CCCCCCEEEEEEEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCC DVPRALDERRILWAAGDIVENRPPLSRWHADYAEAFAAFVKQ CCCHHHHHCEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHCC >Mature Secondary Structure SHPALSPDQTAVVTGGASGIGLAAAKRFAARGMNVCIADVDDARLREAATQVTAEATRG CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCC GAAIMTAKVDVGSRDSVAALEEAVRQRFGAVDVLMNNAGIQPGSRMFGPEETWQRILGVN CEEEEEEEECCCCCCHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCCHHHHHHHHHCCC LWGIIHGSQVFAPGMIAQGRPALIINTGSKQGITTPPGDPAYNVSKAGVKAFTEALQHEL EEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH RNTRDCQVTAHLFIPGFVFTPLTANGRVEKPAAAWTPEQTVDFMLERVQAGDFYVLCPDN CCCCCCEEEEEEEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCC DVPRALDERRILWAAGDIVENRPPLSRWHADYAEAFAAFVKQ CCCHHHHHCEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA