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The map label for this gene is fusA [C]

Identifier: 146342793

GI number: 146342793

Start: 6201195

End: 6203243

Strand: Reverse

Name: fusA [C]

Synonym: BRADO5970

Alternate gene names: 146342793

Gene position: 6203243-6201195 (Counterclockwise)

Preceding gene: 146342794

Following gene: 146342792

Centisome position: 83.19

GC content: 67.59

Gene sequence:

>2049_bases
ATGGGACAAGACCTGAGAAGTCCCCGAGGTCCACGGTGCATCGCGCTGGTGGGCCCTTTCCAAAGCGGTAAGACCACTCT
GTTGGAAGCGATCCTGGCGCGGACGGGCGCGATCCCGCGCGCCGGCAGCGTCGATGCCGGCACCTGCGTCGGCGATGCCA
GCCCGGAGGCGCGCCATCACAAAATGAGCGTCGCGATGACGGCGGCGACCACGACCTTCATGGGCGACAGCTATACTTTC
CTCGACTGCCCCGGCTCGATCGAGTTCGCGCACGACATGCGCGCCGCGTTGCCCGCCGTGGACGCCGCGATCGTGGTCTG
CGAGGCGGACGAGAAGAAGCTGCCGCAATTGCAGATCATCCTGCGCGAGTTGGAGGAACTGCGCATTCCGCGCTTCCTGT
TTCTCAACAAGATCGATCGCGCCAATGCGCGGATCAGGGAAACGCTCGCCACCTTGCAGCCGGCCTCGCGCGTACCGCTG
GTGCTGCGGCAGATTCCGATCTGGCATGGCGAACTGATCGAGGGCTTCGTCGATCTCGCGCTGGAGCGCGCCTTCATCTA
TCGCGAGCACAAGGCATCGGAGGTGATCGCGCTCGAAGGCGGCGATCTCGACCGTGAGAAGGAGGCGCGCTTCTCGATGC
TGGAGAAGCTTGCCGATCACGACGACGCGCTGATGGAGCAACTGCTCGAGGACATCCCGCCGCCGCGCGACGCCGTGTTC
GATGATCTCGCCCGCGAATTGCGCGAGGGCCTGATCTGCCCGGTGCTGCTCGGCTCCGCCTTGCGCGAGAACGGCGTGCT
CCGACTGATGAAGGCGCTGCGCCACGAGGCGCCCGGTATTGCCGAGACCGCGCAGCGGCTCGGCGTGAAAGCGAGCAAGG
AGGCGCTCGGCTACGTCTTCAAGACGCTGCATCTGCAGCATGGCGGCAAGCTGTCGCTGACGCGCGTGCTGGCGGGACAT
CTCGACGACGGCGCCACGTTGCATGCCGCCTCCGGCGAGGCGGCGCGCGTCTCCGGCATCCTCGCCGCGACCGGCGCCTA
TGACAGCAAGCGTGCGGCAGCGGAAGCTGGCGACACGATCGCGCTCGGCAAGCTCGATACCGTCAAGACCGGCGATACCA
TCGCCACCGGCAAGGCCGCGCCTCCGGCGCTCGCGAAGATTGCTCCGTGTCCGCCGGTGCTGGCGCTCTCGATCGCCGCC
GTCGACCGCAAGGATGACGTCAAGCTCGGCCAGGCGCTGCTGCGGCTGAACGAGGAAGATCCGTCGCTGACGATGGTGCA
GAACCAGCGGACGCACGATACCGTGCTGTGGGGACAGGGCGAGATGCATCTGCGCGTCGCCCTGGAGCGCCTGCGCGACC
GCTTCGGGGTCAATGTCAAATCGCATGCGCCGGCGATCGGCTATCAGGAGACCATCCGCAAATCGATCACGCAGCGCGGC
CGGCACAAGAAGCAGTCCGGCGGCCACGGCCAGTTCGGCGACGTCGTGCTCGACATCAGACCTCTGCCGCGCGGTGAAGG
CTTCCGCTTTGCCGAGAAGGTGGTCGGCGGCGCCGTGCCGCGCAACTACATCCCGGCGGTGGAGGAGGGCGTCGTCGACG
CGCTGGCGCGGGGGCCGCTCGGCTTTCCGGTAATCGATGTCGAGGTTACGCTCACTGACGGCTCGTATCACAGCGTGGAT
TCGTCCGACCTCGCCTTCCGCACAGCGGCGCGGGCGGGCGTCGGCGAGGGACTGCCGCAATGTGCGCCGGTGCTGCTGGA
GCCGATCCACACCGTGGAGATCGTTTGTCCGACGGACGCGACCGCCAGGATCAACGCGATCCTGGCGGCGCGGCGCGGCC
AGATCCTATCGTTCGACACCCGCGACGGCTGGCCGGGCTGGGATTGCGTCCGCGCAATGATGCCGGAAGCCGAGATCGGC
GAACTGATCGTCGAGCTGCGCTCAGCCACCGCAGGCGCCGGCAGCTTCACCCGGACCTTCGACCATATGGCCGAGGTGAC
GGGCCGCGCCGCCGACCACATCATCGCCTCGCACCGCGACGCGGCGTAG

Upstream 100 bases:

>100_bases
TTTTTCGCGGGACCCCTGCTTGCCAAAGCGGCAGACGAGGCAGAGCATTCGGCTTTGCCGACCCAATCACGGGCCGAGCT
CCAGAAACAGGAGGCGGCGA

Downstream 100 bases:

>100_bases
ATCGCGTCGCCGCAGCAGGGCCGGCCCGCCCACCTCCACGAGAGGACTGGCGGGCCGATGTCTCGCGCGCAAGCGCATGG
CGTTCGGGACCGCATGCTCA

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MGQDLRSPRGPRCIALVGPFQSGKTTLLEAILARTGAIPRAGSVDAGTCVGDASPEARHHKMSVAMTAATTTFMGDSYTF
LDCPGSIEFAHDMRAALPAVDAAIVVCEADEKKLPQLQIILRELEELRIPRFLFLNKIDRANARIRETLATLQPASRVPL
VLRQIPIWHGELIEGFVDLALERAFIYREHKASEVIALEGGDLDREKEARFSMLEKLADHDDALMEQLLEDIPPPRDAVF
DDLARELREGLICPVLLGSALRENGVLRLMKALRHEAPGIAETAQRLGVKASKEALGYVFKTLHLQHGGKLSLTRVLAGH
LDDGATLHAASGEAARVSGILAATGAYDSKRAAAEAGDTIALGKLDTVKTGDTIATGKAAPPALAKIAPCPPVLALSIAA
VDRKDDVKLGQALLRLNEEDPSLTMVQNQRTHDTVLWGQGEMHLRVALERLRDRFGVNVKSHAPAIGYQETIRKSITQRG
RHKKQSGGHGQFGDVVLDIRPLPRGEGFRFAEKVVGGAVPRNYIPAVEEGVVDALARGPLGFPVIDVEVTLTDGSYHSVD
SSDLAFRTAARAGVGEGLPQCAPVLLEPIHTVEIVCPTDATARINAILAARRGQILSFDTRDGWPGWDCVRAMMPEAEIG
ELIVELRSATAGAGSFTRTFDHMAEVTGRAADHIIASHRDAA

Sequences:

>Translated_682_residues
MGQDLRSPRGPRCIALVGPFQSGKTTLLEAILARTGAIPRAGSVDAGTCVGDASPEARHHKMSVAMTAATTTFMGDSYTF
LDCPGSIEFAHDMRAALPAVDAAIVVCEADEKKLPQLQIILRELEELRIPRFLFLNKIDRANARIRETLATLQPASRVPL
VLRQIPIWHGELIEGFVDLALERAFIYREHKASEVIALEGGDLDREKEARFSMLEKLADHDDALMEQLLEDIPPPRDAVF
DDLARELREGLICPVLLGSALRENGVLRLMKALRHEAPGIAETAQRLGVKASKEALGYVFKTLHLQHGGKLSLTRVLAGH
LDDGATLHAASGEAARVSGILAATGAYDSKRAAAEAGDTIALGKLDTVKTGDTIATGKAAPPALAKIAPCPPVLALSIAA
VDRKDDVKLGQALLRLNEEDPSLTMVQNQRTHDTVLWGQGEMHLRVALERLRDRFGVNVKSHAPAIGYQETIRKSITQRG
RHKKQSGGHGQFGDVVLDIRPLPRGEGFRFAEKVVGGAVPRNYIPAVEEGVVDALARGPLGFPVIDVEVTLTDGSYHSVD
SSDLAFRTAARAGVGEGLPQCAPVLLEPIHTVEIVCPTDATARINAILAARRGQILSFDTRDGWPGWDCVRAMMPEAEIG
ELIVELRSATAGAGSFTRTFDHMAEVTGRAADHIIASHRDAA
>Mature_681_residues
GQDLRSPRGPRCIALVGPFQSGKTTLLEAILARTGAIPRAGSVDAGTCVGDASPEARHHKMSVAMTAATTTFMGDSYTFL
DCPGSIEFAHDMRAALPAVDAAIVVCEADEKKLPQLQIILRELEELRIPRFLFLNKIDRANARIRETLATLQPASRVPLV
LRQIPIWHGELIEGFVDLALERAFIYREHKASEVIALEGGDLDREKEARFSMLEKLADHDDALMEQLLEDIPPPRDAVFD
DLARELREGLICPVLLGSALRENGVLRLMKALRHEAPGIAETAQRLGVKASKEALGYVFKTLHLQHGGKLSLTRVLAGHL
DDGATLHAASGEAARVSGILAATGAYDSKRAAAEAGDTIALGKLDTVKTGDTIATGKAAPPALAKIAPCPPVLALSIAAV
DRKDDVKLGQALLRLNEEDPSLTMVQNQRTHDTVLWGQGEMHLRVALERLRDRFGVNVKSHAPAIGYQETIRKSITQRGR
HKKQSGGHGQFGDVVLDIRPLPRGEGFRFAEKVVGGAVPRNYIPAVEEGVVDALARGPLGFPVIDVEVTLTDGSYHSVDS
SDLAFRTAARAGVGEGLPQCAPVLLEPIHTVEIVCPTDATARINAILAARRGQILSFDTRDGWPGWDCVRAMMPEAEIGE
LIVELRSATAGAGSFTRTFDHMAEVTGRAADHIIASHRDAA

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=701, Percent_Identity=26.3908701854494, Blast_Score=242, Evalue=1e-63,
Organism=Homo sapiens, GI19923640, Length=692, Percent_Identity=25.4335260115607, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI25306287, Length=670, Percent_Identity=25.3731343283582, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI25306283, Length=382, Percent_Identity=25.3926701570681, Blast_Score=112, Evalue=2e-24,
Organism=Escherichia coli, GI1789738, Length=699, Percent_Identity=30.1859799713877, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1790835, Length=462, Percent_Identity=24.6753246753247, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17533571, Length=695, Percent_Identity=28.6330935251799, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17556745, Length=692, Percent_Identity=23.4104046242775, Blast_Score=125, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323098, Length=697, Percent_Identity=27.6901004304161, Blast_Score=245, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6322359, Length=779, Percent_Identity=23.1065468549422, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24582462, Length=695, Percent_Identity=27.7697841726619, Blast_Score=249, Evalue=5e-66,
Organism=Drosophila melanogaster, GI221458488, Length=691, Percent_Identity=25.904486251809, Blast_Score=171, Evalue=2e-42,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 73454; Mature: 73323

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQDLRSPRGPRCIALVGPFQSGKTTLLEAILARTGAIPRAGSVDAGTCVGDASPEARHH
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
KMSVAMTAATTTFMGDSYTFLDCPGSIEFAHDMRAALPAVDAAIVVCEADEKKLPQLQII
HHEEEEEHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHH
LRELEELRIPRFLFLNKIDRANARIRETLATLQPASRVPLVLRQIPIWHGELIEGFVDLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
LERAFIYREHKASEVIALEGGDLDREKEARFSMLEKLADHDDALMEQLLEDIPPPRDAVF
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHH
DDLARELREGLICPVLLGSALRENGVLRLMKALRHEAPGIAETAQRLGVKASKEALGYVF
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
KTLHLQHGGKLSLTRVLAGHLDDGATLHAASGEAARVSGILAATGAYDSKRAAAEAGDTI
HHHHHCCCCCEEHHHHHHHCCCCCCEEEECCCCCHHHHEEEEECCCCCCHHHHHHCCCEE
ALGKLDTVKTGDTIATGKAAPPALAKIAPCPPVLALSIAAVDRKDDVKLGQALLRLNEED
EECCCCCCCCCCCEECCCCCCCHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
PSLTMVQNQRTHDTVLWGQGEMHLRVALERLRDRFGVNVKSHAPAIGYQETIRKSITQRG
CCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
RHKKQSGGHGQFGDVVLDIRPLPRGEGFRFAEKVVGGAVPRNYIPAVEEGVVDALARGPL
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
GFPVIDVEVTLTDGSYHSVDSSDLAFRTAARAGVGEGLPQCAPVLLEPIHTVEIVCPTDA
CCEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCCC
TARINAILAARRGQILSFDTRDGWPGWDCVRAMMPEAEIGELIVELRSATAGAGSFTRTF
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
DHMAEVTGRAADHIIASHRDAA
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GQDLRSPRGPRCIALVGPFQSGKTTLLEAILARTGAIPRAGSVDAGTCVGDASPEARHH
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
KMSVAMTAATTTFMGDSYTFLDCPGSIEFAHDMRAALPAVDAAIVVCEADEKKLPQLQII
HHEEEEEHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHH
LRELEELRIPRFLFLNKIDRANARIRETLATLQPASRVPLVLRQIPIWHGELIEGFVDLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
LERAFIYREHKASEVIALEGGDLDREKEARFSMLEKLADHDDALMEQLLEDIPPPRDAVF
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHH
DDLARELREGLICPVLLGSALRENGVLRLMKALRHEAPGIAETAQRLGVKASKEALGYVF
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
KTLHLQHGGKLSLTRVLAGHLDDGATLHAASGEAARVSGILAATGAYDSKRAAAEAGDTI
HHHHHCCCCCEEHHHHHHHCCCCCCEEEECCCCCHHHHEEEEECCCCCCHHHHHHCCCEE
ALGKLDTVKTGDTIATGKAAPPALAKIAPCPPVLALSIAAVDRKDDVKLGQALLRLNEED
EECCCCCCCCCCCEECCCCCCCHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
PSLTMVQNQRTHDTVLWGQGEMHLRVALERLRDRFGVNVKSHAPAIGYQETIRKSITQRG
CCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
RHKKQSGGHGQFGDVVLDIRPLPRGEGFRFAEKVVGGAVPRNYIPAVEEGVVDALARGPL
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
GFPVIDVEVTLTDGSYHSVDSSDLAFRTAARAGVGEGLPQCAPVLLEPIHTVEIVCPTDA
CCEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCCC
TARINAILAARRGQILSFDTRDGWPGWDCVRAMMPEAEIGELIVELRSATAGAGSFTRTF
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
DHMAEVTGRAADHIIASHRDAA
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]