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The map label for this gene is msrB [H]

Identifier: 146342753

GI number: 146342753

Start: 6145853

End: 6146263

Strand: Direct

Name: msrB [H]

Synonym: BRADO5926

Alternate gene names: 146342753

Gene position: 6145853-6146263 (Clockwise)

Preceding gene: 146342752

Following gene: 146342754

Centisome position: 82.42

GC content: 65.21

Gene sequence:

>411_bases
ATGAGCGACACGAAAACCAGCGACAAGGTCGTCAAGAGCGAGGCCGAGTGGCGCAAGGACCTGACGCCGATGCAGTACGC
CGTGCTGCGCGAAAAGGCGACCGAGCGCCCGTTTTCGGGCGAATATGAGCACGAGCACCGCGCGGGCACCTATGTCTGCG
CCGGCTGCGGCCAGACGCTGTTCGAGTCCGATGCCAAGTTCGATTCCGGCTGCGGCTGGCCGAGCTTCACCCAGCCGGCG
GCCGAGAGCCACATCGACGAGGAGACCGACTATACCCATGGCATGGTTCGCACCGAGGTGCTGTGCTCGAAATGCTCGGG
CCATCTCGGCCACGTCTTCCCGGACGGGCCCGGACCGACCGGTCTGCGCTACTGCATCAACTCGGCGGCACTGAAACTGA
AGCCGCGCTGA

Upstream 100 bases:

>100_bases
CTGGTCAGGGACGCCAAGGCGACGAATTGAGCGCCGCCTCCTGCCCGATCAGCACAACGACAGGGGTGGATCACTTTGGG
TCCGCCGGAGGAACGAAGAG

Downstream 100 bases:

>100_bases
GCCACTTCCGCTCGCCCTCCGGTACCGTTCCGTTGATGGTATCGGAGGGCCTGCATGGCCCTGAAGGAGGGGCGCGACGG
GTCAAAATCAGCCACAGCAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSDTKTSDKVVKSEAEWRKDLTPMQYAVLREKATERPFSGEYEHEHRAGTYVCAGCGQTLFESDAKFDSGCGWPSFTQPA
AESHIDEETDYTHGMVRTEVLCSKCSGHLGHVFPDGPGPTGLRYCINSAALKLKPR

Sequences:

>Translated_136_residues
MSDTKTSDKVVKSEAEWRKDLTPMQYAVLREKATERPFSGEYEHEHRAGTYVCAGCGQTLFESDAKFDSGCGWPSFTQPA
AESHIDEETDYTHGMVRTEVLCSKCSGHLGHVFPDGPGPTGLRYCINSAALKLKPR
>Mature_135_residues
SDTKTSDKVVKSEAEWRKDLTPMQYAVLREKATERPFSGEYEHEHRAGTYVCAGCGQTLFESDAKFDSGCGWPSFTQPAA
ESHIDEETDYTHGMVRTEVLCSKCSGHLGHVFPDGPGPTGLRYCINSAALKLKPR

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=131, Percent_Identity=54.1984732824427, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI301336162, Length=131, Percent_Identity=54.1984732824427, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI73089054, Length=131, Percent_Identity=54.1984732824427, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI37620216, Length=131, Percent_Identity=54.1984732824427, Blast_Score=144, Evalue=2e-35,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=52.6717557251908, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=51.2396694214876, Blast_Score=137, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553450, Length=125, Percent_Identity=46.4, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=125, Percent_Identity=46.4, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=137, Percent_Identity=43.7956204379562, Blast_Score=118, Evalue=3e-28,
Organism=Drosophila melanogaster, GI221378664, Length=128, Percent_Identity=50, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI221378662, Length=135, Percent_Identity=48.1481481481481, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24645799, Length=128, Percent_Identity=47.65625, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45553335, Length=128, Percent_Identity=47.65625, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356369, Length=128, Percent_Identity=47.65625, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645801, Length=139, Percent_Identity=43.8848920863309, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=43.8848920863309, Blast_Score=126, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15061; Mature: 14930

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTKTSDKVVKSEAEWRKDLTPMQYAVLREKATERPFSGEYEHEHRAGTYVCAGCGQTL
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHH
FESDAKFDSGCGWPSFTQPAAESHIDEETDYTHGMVRTEVLCSKCSGHLGHVFPDGPGPT
HHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
GLRYCINSAALKLKPR
HHHHHHHHHCEEECCC
>Mature Secondary Structure 
SDTKTSDKVVKSEAEWRKDLTPMQYAVLREKATERPFSGEYEHEHRAGTYVCAGCGQTL
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHH
FESDAKFDSGCGWPSFTQPAAESHIDEETDYTHGMVRTEVLCSKCSGHLGHVFPDGPGPT
HHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
GLRYCINSAALKLKPR
HHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]