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The map label for this gene is norD [H]

Identifier: 146342693

GI number: 146342693

Start: 6078060

End: 6080342

Strand: Direct

Name: norD [H]

Synonym: BRADO5860

Alternate gene names: 146342693

Gene position: 6078060-6080342 (Clockwise)

Preceding gene: 146342692

Following gene: 146342711

Centisome position: 81.51

GC content: 71.35

Gene sequence:

>2283_bases
GTGAGCGGCGCGGAAGGGCACACCCGCACGCTGCATCTGTGGATGCGCCAGCGCGAGACGTTGCGGCCGTTGTTCATTGC
CGCGTGGGACACGCTGTCGCGCCGCTTCGATCCGCCCGTGATGGAGGCATGGGCCGGCGCGGTGCTCACTCTCGCCAACG
TCAATGCAGGCGCGGCCTGCCTGATCGCCTATTGGGATGCGAGCACCAGCGACGCCGCGGACGAGATCGCGCCGCTGCTC
GGCGCCGCGCAGGCCGCCGCCGAGATCTGCCGCCATGCCGGCGCGCCGGCGGCGACCAGCGCCTTGAAGGCGCTGCCCGC
CGCGCGCCGCATCCTCGGGCGCGGCGCGGCGCTATCGCGCTGGTGGCGGACGATGACGGCGCTGGCAACCCAGGCGCCGG
AGTCGCTCGCGGCCGCGGCGGGCCACATGCCCGAGATCCTGCGGCCGGGCACGATCGAGGCGTTCGAAAGCTTTGTCGCC
TCCGGCCTGCGCGCTGCCGCCGGCGACCGCCGCAAGCGGCTCGCGTTTTTTTCGCTGCAGGACGAGCTGGCGCTGCGGCT
GATCGCGCGCGATCCCGGCGCGGTGACGTTCGCCGACGTCGAGACCGAGCTGAAGGCTTTTCTCACGGCGTTGTTCGGCG
AGGTGCCGCTGCTGCGAAGCATGGCGGTGGACGGCGGCCAGACGCCGCAACGCCGCGTGGCGATCGCTGGGCCGCTGATC
CGCCTGCCCGAGATCTATCGCGGCACGCAAGGCGCGGCGGCGCGCGCGTTGTTTCGCGCGGCCGCGGCCCATGCGCAGGC
GCATCTCGTGCTCGGACGCGCGCGCTTTGCTGTCGGGCAGCTCAAGCCGCTGCAGCTCGCACTGGTCAACCTGATCGAGG
ACGCCCGCGTCGAAACGCTTGCGATGCGCGACTTTTCGGGCCTGCGGCGGCTGTGGGCGCCATACCATGTCGCCGTCCCG
ACCAGCGTCGCGACGGCGCCGATGCTGCTGGCACGGCTGGCGCGCGCCTTGTTCGATCCGTCCTATCGCGATGAGGACGG
CTTCGTCAGCAAGGGCCGCGCGCTGTTCACCGCGGCGCTGCCGCGCCTCGACGATCACGCCATCAGCCGCGAGATCGGCA
TGCTGCTCGGCAACGATCTCGGCCAGATGCGCGTGCAGTTCAACGCCAAGACCTATGTCGTCGAGCCGCTCTATCGCGAC
GATGGTCTCGGCCTGTGGGAGTTCGACGGCGATGCGGCTCCGTCGGCCGAGGTGCTCGAGCTGTTCATCGATGCGGTCAG
ACCGGAGCAGCAGGAGAGCGAGAGCGGCGAACGGCGCGAGCAGGATGAGGACAACGCGGCGGCCGAGCCCGGACGCGCCC
GCCCCGTCGCGCCGGACGCGCGCGGCGTCATGCTGGCGCGCTATCCGGAATGGGATCGCGTCGATGCGATCGAGCGGCCG
GACTGGACCACTGTGCGCGAGGTCGCGGCCGGAAGCGGCGGCTCGCATGCCATCGAGGACGCACTGGAGCAGGCCAGCAG
CTTGCGCAGCCGTGTCGCGCGGCTGGTCCGCGCCGTCCGCATCGGCCGCACCGTTCGGCTGAAGCGCCAGCAGGACGGCC
ACGACCTCGACCTCGACGCCGTGCTCGACGCCGGGATCGCGCTCCGCGGCGGCGAGATGCCGGATCCGCGCGTCTTCCGG
TCGGCCAAGGCGCTGCATCGCGACCTCTCGGCGCTGCTGCTGATCGACGTGTCGGAATCGACACGCGACCGTCTGGCGTC
GGGCGCGACGGTCCTCGATCTCGAACGCCTGGCCGTCGCTCTGCTGGCCGAGGCGATGGACCAGCTCGGCGACACGTTCG
GGCTGCTCGCATTCGCCTCCGACGGCCGCGACGACATCCGGATGACGAGCATCAAGAACTTCGGCGAAGCCTATGACCGC
GATTGCCGCGCAAGGCTCGCGGGCCTCGTGTCCGGACTGTCCACACGTCTGGGCGCGGCATTGCGCCATGCCGGCGCCGT
GCTCGGCGTAGCAACAAGCAGCCGCAAGCTGCTGATCGTGCTCACCGACGGCGAGCCGTCCGACATCGACGTCTCCGATC
CGCTCGACCTGATCGAGGACGCCCGTCGCGCCGCGCTCGGGCTGCACGCGCAGGGCATCGATGCCTATGGCGTCGTGCTT
GGCCGGGCCGGCGCGGAGGCCGCGACGCGCGTCTTCGGCCGCGGCAACACCATGCTGGTGCACCGGGTCGAGGATCTGCC
GGCGCGGCTGTCCGAACTCTATTTCAGGCTGGCGCGGCGATGA

Upstream 100 bases:

>100_bases
CCGGCATCGTGCTGCCGATCACCGACAATCCGGATATCCGCGTCGCGCTCTCCGACGCGATCGCGGCGTGCCTGCCGTGA
GCGCGGCGCCGCTGCAGCTG

Downstream 100 bases:

>100_bases
GGCTATTTGCGCCGGCGCGACAACGTCACGCCCAGCGCGGCCGCCGCTGCGACGTGGAACGCCGCATCCGTTGCGCGCGA
CAAGGTGCCGCCATCGGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MSGAEGHTRTLHLWMRQRETLRPLFIAAWDTLSRRFDPPVMEAWAGAVLTLANVNAGAACLIAYWDASTSDAADEIAPLL
GAAQAAAEICRHAGAPAATSALKALPAARRILGRGAALSRWWRTMTALATQAPESLAAAAGHMPEILRPGTIEAFESFVA
SGLRAAAGDRRKRLAFFSLQDELALRLIARDPGAVTFADVETELKAFLTALFGEVPLLRSMAVDGGQTPQRRVAIAGPLI
RLPEIYRGTQGAAARALFRAAAAHAQAHLVLGRARFAVGQLKPLQLALVNLIEDARVETLAMRDFSGLRRLWAPYHVAVP
TSVATAPMLLARLARALFDPSYRDEDGFVSKGRALFTAALPRLDDHAISREIGMLLGNDLGQMRVQFNAKTYVVEPLYRD
DGLGLWEFDGDAAPSAEVLELFIDAVRPEQQESESGERREQDEDNAAAEPGRARPVAPDARGVMLARYPEWDRVDAIERP
DWTTVREVAAGSGGSHAIEDALEQASSLRSRVARLVRAVRIGRTVRLKRQQDGHDLDLDAVLDAGIALRGGEMPDPRVFR
SAKALHRDLSALLLIDVSESTRDRLASGATVLDLERLAVALLAEAMDQLGDTFGLLAFASDGRDDIRMTSIKNFGEAYDR
DCRARLAGLVSGLSTRLGAALRHAGAVLGVATSSRKLLIVLTDGEPSDIDVSDPLDLIEDARRAALGLHAQGIDAYGVVL
GRAGAEAATRVFGRGNTMLVHRVEDLPARLSELYFRLARR

Sequences:

>Translated_760_residues
MSGAEGHTRTLHLWMRQRETLRPLFIAAWDTLSRRFDPPVMEAWAGAVLTLANVNAGAACLIAYWDASTSDAADEIAPLL
GAAQAAAEICRHAGAPAATSALKALPAARRILGRGAALSRWWRTMTALATQAPESLAAAAGHMPEILRPGTIEAFESFVA
SGLRAAAGDRRKRLAFFSLQDELALRLIARDPGAVTFADVETELKAFLTALFGEVPLLRSMAVDGGQTPQRRVAIAGPLI
RLPEIYRGTQGAAARALFRAAAAHAQAHLVLGRARFAVGQLKPLQLALVNLIEDARVETLAMRDFSGLRRLWAPYHVAVP
TSVATAPMLLARLARALFDPSYRDEDGFVSKGRALFTAALPRLDDHAISREIGMLLGNDLGQMRVQFNAKTYVVEPLYRD
DGLGLWEFDGDAAPSAEVLELFIDAVRPEQQESESGERREQDEDNAAAEPGRARPVAPDARGVMLARYPEWDRVDAIERP
DWTTVREVAAGSGGSHAIEDALEQASSLRSRVARLVRAVRIGRTVRLKRQQDGHDLDLDAVLDAGIALRGGEMPDPRVFR
SAKALHRDLSALLLIDVSESTRDRLASGATVLDLERLAVALLAEAMDQLGDTFGLLAFASDGRDDIRMTSIKNFGEAYDR
DCRARLAGLVSGLSTRLGAALRHAGAVLGVATSSRKLLIVLTDGEPSDIDVSDPLDLIEDARRAALGLHAQGIDAYGVVL
GRAGAEAATRVFGRGNTMLVHRVEDLPARLSELYFRLARR
>Mature_759_residues
SGAEGHTRTLHLWMRQRETLRPLFIAAWDTLSRRFDPPVMEAWAGAVLTLANVNAGAACLIAYWDASTSDAADEIAPLLG
AAQAAAEICRHAGAPAATSALKALPAARRILGRGAALSRWWRTMTALATQAPESLAAAAGHMPEILRPGTIEAFESFVAS
GLRAAAGDRRKRLAFFSLQDELALRLIARDPGAVTFADVETELKAFLTALFGEVPLLRSMAVDGGQTPQRRVAIAGPLIR
LPEIYRGTQGAAARALFRAAAAHAQAHLVLGRARFAVGQLKPLQLALVNLIEDARVETLAMRDFSGLRRLWAPYHVAVPT
SVATAPMLLARLARALFDPSYRDEDGFVSKGRALFTAALPRLDDHAISREIGMLLGNDLGQMRVQFNAKTYVVEPLYRDD
GLGLWEFDGDAAPSAEVLELFIDAVRPEQQESESGERREQDEDNAAAEPGRARPVAPDARGVMLARYPEWDRVDAIERPD
WTTVREVAAGSGGSHAIEDALEQASSLRSRVARLVRAVRIGRTVRLKRQQDGHDLDLDAVLDAGIALRGGEMPDPRVFRS
AKALHRDLSALLLIDVSESTRDRLASGATVLDLERLAVALLAEAMDQLGDTFGLLAFASDGRDDIRMTSIKNFGEAYDRD
CRARLAGLVSGLSTRLGAALRHAGAVLGVATSSRKLLIVLTDGEPSDIDVSDPLDLIEDARRAALGLHAQGIDAYGVVLG
RAGAEAATRVFGRGNTMLVHRVEDLPARLSELYFRLARR

Specific function: Part of the operon norEFCBQD encoding nitric oxide reductase. Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection [H]

COG id: COG4548

COG function: function code P; Nitric oxide reductase activation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 82094; Mature: 81962

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAEGHTRTLHLWMRQRETLRPLFIAAWDTLSRRFDPPVMEAWAGAVLTLANVNAGAAC
CCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCEE
LIAYWDASTSDAADEIAPLLGAAQAAAEICRHAGAPAATSALKALPAARRILGRGAALSR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHH
WWRTMTALATQAPESLAAAAGHMPEILRPGTIEAFESFVASGLRAAAGDRRKRLAFFSLQ
HHHHHHHHHHHCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEHH
DELALRLIARDPGAVTFADVETELKAFLTALFGEVPLLRSMAVDGGQTPQRRVAIAGPLI
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHEEEECCCCH
RLPEIYRGTQGAAARALFRAAAAHAQAHLVLGRARFAVGQLKPLQLALVNLIEDARVETL
HCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AMRDFSGLRRLWAPYHVAVPTSVATAPMLLARLARALFDPSYRDEDGFVSKGRALFTAAL
HHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHH
PRLDDHAISREIGMLLGNDLGQMRVQFNAKTYVVEPLYRDDGLGLWEFDGDAAPSAEVLE
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCEECCCCCEEEECCCCCCCHHHHHH
LFIDAVRPEQQESESGERREQDEDNAAAEPGRARPVAPDARGVMLARYPEWDRVDAIERP
HHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
DWTTVREVAAGSGGSHAIEDALEQASSLRSRVARLVRAVRIGRTVRLKRQQDGHDLDLDA
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHH
VLDAGIALRGGEMPDPRVFRSAKALHRDLSALLLIDVSESTRDRLASGATVLDLERLAVA
HHHCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHH
LLAEAMDQLGDTFGLLAFASDGRDDIRMTSIKNFGEAYDRDCRARLAGLVSGLSTRLGAA
HHHHHHHHHCCHHEEEEEECCCCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LRHAGAVLGVATSSRKLLIVLTDGEPSDIDVSDPLDLIEDARRAALGLHAQGIDAYGVVL
HHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
GRAGAEAATRVFGRGNTMLVHRVEDLPARLSELYFRLARR
CCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGAEGHTRTLHLWMRQRETLRPLFIAAWDTLSRRFDPPVMEAWAGAVLTLANVNAGAAC
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCEE
LIAYWDASTSDAADEIAPLLGAAQAAAEICRHAGAPAATSALKALPAARRILGRGAALSR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHH
WWRTMTALATQAPESLAAAAGHMPEILRPGTIEAFESFVASGLRAAAGDRRKRLAFFSLQ
HHHHHHHHHHHCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEHH
DELALRLIARDPGAVTFADVETELKAFLTALFGEVPLLRSMAVDGGQTPQRRVAIAGPLI
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHEEEECCCCH
RLPEIYRGTQGAAARALFRAAAAHAQAHLVLGRARFAVGQLKPLQLALVNLIEDARVETL
HCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AMRDFSGLRRLWAPYHVAVPTSVATAPMLLARLARALFDPSYRDEDGFVSKGRALFTAAL
HHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHH
PRLDDHAISREIGMLLGNDLGQMRVQFNAKTYVVEPLYRDDGLGLWEFDGDAAPSAEVLE
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCEECCCCCEEEECCCCCCCHHHHHH
LFIDAVRPEQQESESGERREQDEDNAAAEPGRARPVAPDARGVMLARYPEWDRVDAIERP
HHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
DWTTVREVAAGSGGSHAIEDALEQASSLRSRVARLVRAVRIGRTVRLKRQQDGHDLDLDA
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHH
VLDAGIALRGGEMPDPRVFRSAKALHRDLSALLLIDVSESTRDRLASGATVLDLERLAVA
HHHCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHH
LLAEAMDQLGDTFGLLAFASDGRDDIRMTSIKNFGEAYDRDCRARLAGLVSGLSTRLGAA
HHHHHHHHHCCHHEEEEEECCCCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LRHAGAVLGVATSSRKLLIVLTDGEPSDIDVSDPLDLIEDARRAALGLHAQGIDAYGVVL
HHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
GRAGAEAATRVFGRGNTMLVHRVEDLPARLSELYFRLARR
CCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA