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The map label for this gene is arcA [H]

Identifier: 146342173

GI number: 146342173

Start: 5539778

End: 5540752

Strand: Reverse

Name: arcA [H]

Synonym: BRADO5323

Alternate gene names: 146342173

Gene position: 5540752-5539778 (Counterclockwise)

Preceding gene: 146342175

Following gene: 146342170

Centisome position: 74.31

GC content: 66.46

Gene sequence:

>975_bases
GTGGCACCATCAGACCCAGCATCGCCGCACCGCATCGCCGTGCTCGGTGCACCGATCGATCTCGGCGCCTCCGTCCGGGG
GACGCTGATGGGCCCCGCGGCGTTGCGGACCGCGGGTCTCGTCCCTGTGCTGGAAAGCCTTGGGCTCGAGGTCACGGACT
ACGGCGATGTCGGCATTGCCGACATGGCCGAGCTCGGTGATGACCCGCCTTCCAGCGCCAAGCATTATCGCCAGATCCAG
CGCTGGTCGCGGGTGCTGGCGCGCCGCAGCTACGAATTGGCGCAGACCGGAGCTCTTCCTGTGTTCCTGGGGGGCGATCA
TTCCCTGTCGATGGGATCGGTCAATGGCATCGCCCGTCACTGCCGCGATATCGGGCGTGAGCTGTTCGTGCTCTGGCTCG
ATGCGCATGCCGACTACAACACGCCTGCGACGACCATCACCGCCAACATGCACGGCATGTCGGCGGCGTTCCTGTGCGGC
GAGCCGGGGCTGGATGGGCTGCTCGGCGACGAGCCGCGGGTCGGCATCTCATCGGCGCAGCTCGAGCTGTTCGGCATCCG
CTCGATCGACAAGGCGGAGAAGGATCTGCTGCGGCTGCGGCGCGTCAGCATCGCCGACATGCGCGCGATCGACGAGTTCG
GCGTAGGTGTCCTGATGCGCAGGGTGCTCGACAAGGTCCGTGCCCGCGACGGCGTTCTGCATGTCAGCTTCGACGTCGAC
TTTCTCGATCCCGACGTGGCGCCCGGCGTGGGGACCACCGTGCCGGGTGGCGCGACCTATCGCGAGGCGCATCTCATCAT
GGAGCTGCTGCACGATTCTGGACTGGTCTGCTCGGTCGACATCGTCGAGCTCAATCCGTTTCTCGACGATCGCGGCAAGA
CCGCGCGTGTCGCCGTCGAGCTGATCGGCAGCCTGTTCGGTCAGCAGATCACCGACCGGCCCACCCCGACCAATGCGATC
GTGCCGGATCAATAG

Upstream 100 bases:

>100_bases
TCCGACCGCGAGGCCTCGAAACCGGTGGATCGTAGCCGTCGGGTGCGCCACTCCAGCACCACGCCCGTTATGGTGGGGCG
GATGTTGAAAGGATCTCACA

Downstream 100 bases:

>100_bases
CCGGGTGCCTTCGGCGGGTCGTGGAGACGCGGATGCCTCTTTTGCAAGGCATCCGCGCGAGCGCGATCAGTAGCGCGCGT
CGTACATCTTCGACTCGACG

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAPSDPASPHRIAVLGAPIDLGASVRGTLMGPAALRTAGLVPVLESLGLEVTDYGDVGIADMAELGDDPPSSAKHYRQIQ
RWSRVLARRSYELAQTGALPVFLGGDHSLSMGSVNGIARHCRDIGRELFVLWLDAHADYNTPATTITANMHGMSAAFLCG
EPGLDGLLGDEPRVGISSAQLELFGIRSIDKAEKDLLRLRRVSIADMRAIDEFGVGVLMRRVLDKVRARDGVLHVSFDVD
FLDPDVAPGVGTTVPGGATYREAHLIMELLHDSGLVCSVDIVELNPFLDDRGKTARVAVELIGSLFGQQITDRPTPTNAI
VPDQ

Sequences:

>Translated_324_residues
MAPSDPASPHRIAVLGAPIDLGASVRGTLMGPAALRTAGLVPVLESLGLEVTDYGDVGIADMAELGDDPPSSAKHYRQIQ
RWSRVLARRSYELAQTGALPVFLGGDHSLSMGSVNGIARHCRDIGRELFVLWLDAHADYNTPATTITANMHGMSAAFLCG
EPGLDGLLGDEPRVGISSAQLELFGIRSIDKAEKDLLRLRRVSIADMRAIDEFGVGVLMRRVLDKVRARDGVLHVSFDVD
FLDPDVAPGVGTTVPGGATYREAHLIMELLHDSGLVCSVDIVELNPFLDDRGKTARVAVELIGSLFGQQITDRPTPTNAI
VPDQ
>Mature_323_residues
APSDPASPHRIAVLGAPIDLGASVRGTLMGPAALRTAGLVPVLESLGLEVTDYGDVGIADMAELGDDPPSSAKHYRQIQR
WSRVLARRSYELAQTGALPVFLGGDHSLSMGSVNGIARHCRDIGRELFVLWLDAHADYNTPATTITANMHGMSAAFLCGE
PGLDGLLGDEPRVGISSAQLELFGIRSIDKAEKDLLRLRRVSIADMRAIDEFGVGVLMRRVLDKVRARDGVLHVSFDVDF
LDPDVAPGVGTTVPGGATYREAHLIMELLHDSGLVCSVDIVELNPFLDDRGKTARVAVELIGSLFGQQITDRPTPTNAIV
PDQ

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=341, Percent_Identity=38.7096774193548, Blast_Score=200, Evalue=1e-51,
Organism=Homo sapiens, GI10947139, Length=328, Percent_Identity=35.3658536585366, Blast_Score=185, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71996843, Length=235, Percent_Identity=30.6382978723404, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325146, Length=303, Percent_Identity=28.3828382838284, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24638886, Length=333, Percent_Identity=33.033033033033, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 34674; Mature: 34543

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSDPASPHRIAVLGAPIDLGASVRGTLMGPAALRTAGLVPVLESLGLEVTDYGDVGIA
CCCCCCCCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCEEECCCCCCHH
DMAELGDDPPSSAKHYRQIQRWSRVLARRSYELAQTGALPVFLGGDHSLSMGSVNGIARH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHH
CRDIGRELFVLWLDAHADYNTPATTITANMHGMSAAFLCGEPGLDGLLGDEPRVGISSAQ
HHHHHHEEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCE
LELFGIRSIDKAEKDLLRLRRVSIADMRAIDEFGVGVLMRRVLDKVRARDGVLHVSFDVD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECE
FLDPDVAPGVGTTVPGGATYREAHLIMELLHDSGLVCSVDIVELNPFLDDRGKTARVAVE
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
LIGSLFGQQITDRPTPTNAIVPDQ
HHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
APSDPASPHRIAVLGAPIDLGASVRGTLMGPAALRTAGLVPVLESLGLEVTDYGDVGIA
CCCCCCCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCEEECCCCCCHH
DMAELGDDPPSSAKHYRQIQRWSRVLARRSYELAQTGALPVFLGGDHSLSMGSVNGIARH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHH
CRDIGRELFVLWLDAHADYNTPATTITANMHGMSAAFLCGEPGLDGLLGDEPRVGISSAQ
HHHHHHEEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCE
LELFGIRSIDKAEKDLLRLRRVSIADMRAIDEFGVGVLMRRVLDKVRARDGVLHVSFDVD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECE
FLDPDVAPGVGTTVPGGATYREAHLIMELLHDSGLVCSVDIVELNPFLDDRGKTARVAVE
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
LIGSLFGQQITDRPTPTNAIVPDQ
HHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2806247; 3040404; 11743193; 11743194 [H]