Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 146342119

GI number: 146342119

Start: 5475904

End: 5476797

Strand: Direct

Name: livH [H]

Synonym: BRADO5265

Alternate gene names: 146342119

Gene position: 5475904-5476797 (Clockwise)

Preceding gene: 146342118

Following gene: 146342120

Centisome position: 73.44

GC content: 61.97

Gene sequence:

>894_bases
ATGAACACCGCCTTCCTCATCCAGCTCCTCGTCAACGGCCTCGTGGTCGGCACGCTCTATGGCGTGGTCGCGATGTCGTT
CGTGCTGATCTACAAGGCCACGCAGGTCGTCAATTTCGCGCAAGGCGAGCTGCTCTTGATCGGCGCCTGGGTGTGCTGGA
CGCTGCTCACCAAATTCCAGGTGCCGTTCTGGGCCGGCATGCCGCTGTCGCTGATCTTCATGTTCGCCTTCGGCATCGCG
ATCCAGGTCGTCATCCTCCGGCCGATGATCGGCGAGCCCATCATCTCCGTCATCATGGTGACGATCGGCCTGTCGACCGT
GTTCCAGGCCGCGCTGAAATGGATCTACGGCGTCAACCCGCAGCCGTTCCCGCCGGTGTTTTCCAGCAAAGCGGTCGACA
TCTTCGGGCTGCAGATCCAGACCGTCTATGTGATGAGCCTCGTCGTCTCCGTGCTGATGATGCTCGGCATGGCCTGGTTC
TTCAAAGCCTCAAAATATGGCCTCGCCATGCGCGCCACCGCCTTCAATCAGCAGGTCGCGCAGTCGCTCGGCATCTCCGT
GAAGAGCGTGTTCGCGATGGCCTGGGCGATCTCGGCGACCGTCTCGGCCGTCGCCGGCGTCGTCGTCGCCGTGGTCAACG
GCGTGTCCTCGGGACTGTCGGCCTACGGCATCAAGGTGTTTCCCGCGGCGATCCTCGGCGGTCTCGACTCCGTCGGCGGC
GCCGTGCTCGGCGGCATCATCATCGGCCTCCTGGAGAACATCGCCCAATATGTCGACAGCCAGTACCTGCACTGGGGCAA
TCTCTACGAGATCGCGCCGTTCTACGTTCTGATCATCATCCTGATGATCAAGCCCTACGGCCTGTTCGGCACCAGAGACA
TCGAGCGGATATGA

Upstream 100 bases:

>100_bases
GAACGCAGCCGAGGGTGGGCACGCTTCGCTTTGCCCACCCTACAATCCCTCTCGCCAGGGATCGCCGGGTCAAGCCCGGC
GATGACGAGTGAGACCGATC

Downstream 100 bases:

>100_bases
GCATGATCGCCGAAAAGTGGGCACCGGTTTTCGGTAACGATCATGCTCGAACAAAAGAGAAGGGCGAGCCCATGACGCAA
CTCAAGCCTGAGGCGAGATA

Product: putative high-affinity branched-chain amino acid transport system permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNTAFLIQLLVNGLVVGTLYGVVAMSFVLIYKATQVVNFAQGELLLIGAWVCWTLLTKFQVPFWAGMPLSLIFMFAFGIA
IQVVILRPMIGEPIISVIMVTIGLSTVFQAALKWIYGVNPQPFPPVFSSKAVDIFGLQIQTVYVMSLVVSVLMMLGMAWF
FKASKYGLAMRATAFNQQVAQSLGISVKSVFAMAWAISATVSAVAGVVVAVVNGVSSGLSAYGIKVFPAAILGGLDSVGG
AVLGGIIIGLLENIAQYVDSQYLHWGNLYEIAPFYVLIIILMIKPYGLFGTRDIERI

Sequences:

>Translated_297_residues
MNTAFLIQLLVNGLVVGTLYGVVAMSFVLIYKATQVVNFAQGELLLIGAWVCWTLLTKFQVPFWAGMPLSLIFMFAFGIA
IQVVILRPMIGEPIISVIMVTIGLSTVFQAALKWIYGVNPQPFPPVFSSKAVDIFGLQIQTVYVMSLVVSVLMMLGMAWF
FKASKYGLAMRATAFNQQVAQSLGISVKSVFAMAWAISATVSAVAGVVVAVVNGVSSGLSAYGIKVFPAAILGGLDSVGG
AVLGGIIIGLLENIAQYVDSQYLHWGNLYEIAPFYVLIIILMIKPYGLFGTRDIERI
>Mature_297_residues
MNTAFLIQLLVNGLVVGTLYGVVAMSFVLIYKATQVVNFAQGELLLIGAWVCWTLLTKFQVPFWAGMPLSLIFMFAFGIA
IQVVILRPMIGEPIISVIMVTIGLSTVFQAALKWIYGVNPQPFPPVFSSKAVDIFGLQIQTVYVMSLVVSVLMMLGMAWF
FKASKYGLAMRATAFNQQVAQSLGISVKSVFAMAWAISATVSAVAGVVVAVVNGVSSGLSAYGIKVFPAAILGGLDSVGG
AVLGGIIIGLLENIAQYVDSQYLHWGNLYEIAPFYVLIIILMIKPYGLFGTRDIERI

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=308, Percent_Identity=28.2467532467532, Blast_Score=117, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 32010; Mature: 32010

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]