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The map label for this gene is caiC [C]

Identifier: 146342118

GI number: 146342118

Start: 5473737

End: 5475665

Strand: Direct

Name: caiC [C]

Synonym: BRADO5264

Alternate gene names: 146342118

Gene position: 5473737-5475665 (Clockwise)

Preceding gene: 146342117

Following gene: 146342119

Centisome position: 73.41

GC content: 65.63

Gene sequence:

>1929_bases
ATGGACTATGCTCGCCGCGTGACGCAGGCCGACACCTATCCAAAGCTGCTGCGCCTGAACGCCAAAGAGCACGGCCAGGA
GATTGCGCTGCGCGAGAAGGATCTCGGGCTGTGGCGGACCTTCACCTGGGCCGACTACCAGGCGCGCGTGCGCGACTTTG
CGCTCGGCATGGTCGATGTCGGGCTCGGCAAGGACGACGTGATCGGAATCATCGGCGACAACAGGCCCGACTGGGTGGCT
GCGGAGATCGCGACGCACGCGATCCGCGGCCACAGCCTCGGCCTCTATCGCGACGTGCTCGACGACGAGGCCGCCTATCT
CCTGAACTACGGCGAAGCGCGGCTGGTGTTCGCCGAGGACGAGGAGCAGGTCGACAAGCTGCTCAACCTCGCCGACCGCG
TGCCGGCACTCAAGCACATCATCTATTCCGATCCGCGCGGCATGCGGAAGTATGACGATCCCAGGCTGATGCCGGCCGAC
AAGCTCGCCGAGCTCGGCCGCGCCCGGGCGGCGCGCGAGCCCGATCTGTACGACCGGATGGTGGATGCGACCGTCGGCGA
CGACGTCGCGATCCTCTGCACCACCTCAGGCACGACATCACATCCCAAGCTGGCGATGCTCTCGGCCGCGCGGGTGCTCA
GGCATTGCGCGAACTATCTCGCGTTCGACCCCAAGGGACCGGAGGACGAATACGTCTCGGTGCTGCCGCTGCCCTGGATC
ATGGAACAGGTCTATGTGCTCGGCAAAGGTCTGCTCTGCCGGATGAAGGTCAACTTCGTCGAAGAGCCGGACACCATGAT
GAACGACTTCCGCGAGATCGCGCCGACGTTCGTCCTGTTTGCGCCGCGGGTGTGGGAGCAGATCGCGGCTGACGTCCGCG
CGGCAGTCATGGACGCCTCGCCGCTGAAGCAGCGGCTGTATCACATCGGCATGTCGGCGGGCCTTGCGGCGCTGGACAAG
GGACAGCATTCCGGCTTCGCCGACATGCTGCTGTTTCGCGCGCTGCGCGACCGGCTCGGCTTCACCCGGCTGCGCTCGGC
CGCCACCGGTGGCGCCGCGCTCGGGCCCGACACGTTCAAATTCTTCCGCGCCATGGGCGTGCCGCTGCGGACCCTGTACG
GCCAGACCGAACTGCTCGGCGCCTATACGCTGCATCCGGACGACAAGGTCGATCCCGACACGACCGGCGTGCCGATGGCC
GCGGACATCGAGATCCGGATCGACCAGCCCGACAGCCAGGGCATCGGCGAGATCCTGGTGCGTCATCCCAACATGTTCCT
AGGGTACTACAAGAACCTGGAAGCCTCGGCCGCCGACATCAAGGACGGCTGGATGCATTCCGGCGATGCCGGCTATTTCA
ACGACGCCAGGCAGCTCGTCGTGATCGACCGCATCAAGGACCTCGCCGAGACGTCGCGCGGCGAGCGCTTCTCGCCGCAA
TATATCGAGAACAAGCTGAAATTCTCGCCCTATATCGCGGAGGCCGTCGTGCTCGGCGCCGGCCGCGAGCACCTCGCGGC
GATGATCTGCATCCGCTACTCGATCATCTCGAAATGGGCGGAGAAGAACCGCATCGCGTTCACCACCTACTCGGATCTCG
CCTCGCGCAACGAGGTCTATGCGCTGCTGCAGAAGGAGGTCGAGACCGTCAACGCGCACCTGCCGCCGGCCCAGCGCATC
GCACGCTTCCTGCTGCTCTACAAGGAGCTCGACGCCGACGACGGCGAACTGACCCGCACCCGCAAGGTTCGCCGCAGCGT
GATCAACGAGAAATACGCCGACATCATCGACGGCATCTACGGCGGCAAGCCGGCCATCCCCGTCGACACCGTCATCCGCT
TCCAGGACGGCACCACGCAGCGCATCCGCACCACGCTGAAGGTGGTGGATCTCGGCGGGCATGGACCGATGTCGGAGGCG
GCGGAGTGA

Upstream 100 bases:

>100_bases
TGCTCGCCGATCCGCACGTCAAGCGCGCCTATCTCGGCGAGGAAGACGAACTGCTCGTCGATCCCGACGAGGCGCCGTCC
ATCGCGGAGGACGCGGCATG

Downstream 100 bases:

>100_bases
TAATGGGCGTTTTGTCATACGAGACCGTCATGCGCGGGCTTGACCCGCGCATCCATCCCGTTGCGAGCAATGCGGATGTC
GGACGGATATCCGTAGGGTG

Product: putative long-chain-fatty-acid-CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MDYARRVTQADTYPKLLRLNAKEHGQEIALREKDLGLWRTFTWADYQARVRDFALGMVDVGLGKDDVIGIIGDNRPDWVA
AEIATHAIRGHSLGLYRDVLDDEAAYLLNYGEARLVFAEDEEQVDKLLNLADRVPALKHIIYSDPRGMRKYDDPRLMPAD
KLAELGRARAAREPDLYDRMVDATVGDDVAILCTTSGTTSHPKLAMLSAARVLRHCANYLAFDPKGPEDEYVSVLPLPWI
MEQVYVLGKGLLCRMKVNFVEEPDTMMNDFREIAPTFVLFAPRVWEQIAADVRAAVMDASPLKQRLYHIGMSAGLAALDK
GQHSGFADMLLFRALRDRLGFTRLRSAATGGAALGPDTFKFFRAMGVPLRTLYGQTELLGAYTLHPDDKVDPDTTGVPMA
ADIEIRIDQPDSQGIGEILVRHPNMFLGYYKNLEASAADIKDGWMHSGDAGYFNDARQLVVIDRIKDLAETSRGERFSPQ
YIENKLKFSPYIAEAVVLGAGREHLAAMICIRYSIISKWAEKNRIAFTTYSDLASRNEVYALLQKEVETVNAHLPPAQRI
ARFLLLYKELDADDGELTRTRKVRRSVINEKYADIIDGIYGGKPAIPVDTVIRFQDGTTQRIRTTLKVVDLGGHGPMSEA
AE

Sequences:

>Translated_642_residues
MDYARRVTQADTYPKLLRLNAKEHGQEIALREKDLGLWRTFTWADYQARVRDFALGMVDVGLGKDDVIGIIGDNRPDWVA
AEIATHAIRGHSLGLYRDVLDDEAAYLLNYGEARLVFAEDEEQVDKLLNLADRVPALKHIIYSDPRGMRKYDDPRLMPAD
KLAELGRARAAREPDLYDRMVDATVGDDVAILCTTSGTTSHPKLAMLSAARVLRHCANYLAFDPKGPEDEYVSVLPLPWI
MEQVYVLGKGLLCRMKVNFVEEPDTMMNDFREIAPTFVLFAPRVWEQIAADVRAAVMDASPLKQRLYHIGMSAGLAALDK
GQHSGFADMLLFRALRDRLGFTRLRSAATGGAALGPDTFKFFRAMGVPLRTLYGQTELLGAYTLHPDDKVDPDTTGVPMA
ADIEIRIDQPDSQGIGEILVRHPNMFLGYYKNLEASAADIKDGWMHSGDAGYFNDARQLVVIDRIKDLAETSRGERFSPQ
YIENKLKFSPYIAEAVVLGAGREHLAAMICIRYSIISKWAEKNRIAFTTYSDLASRNEVYALLQKEVETVNAHLPPAQRI
ARFLLLYKELDADDGELTRTRKVRRSVINEKYADIIDGIYGGKPAIPVDTVIRFQDGTTQRIRTTLKVVDLGGHGPMSEA
AE
>Mature_642_residues
MDYARRVTQADTYPKLLRLNAKEHGQEIALREKDLGLWRTFTWADYQARVRDFALGMVDVGLGKDDVIGIIGDNRPDWVA
AEIATHAIRGHSLGLYRDVLDDEAAYLLNYGEARLVFAEDEEQVDKLLNLADRVPALKHIIYSDPRGMRKYDDPRLMPAD
KLAELGRARAAREPDLYDRMVDATVGDDVAILCTTSGTTSHPKLAMLSAARVLRHCANYLAFDPKGPEDEYVSVLPLPWI
MEQVYVLGKGLLCRMKVNFVEEPDTMMNDFREIAPTFVLFAPRVWEQIAADVRAAVMDASPLKQRLYHIGMSAGLAALDK
GQHSGFADMLLFRALRDRLGFTRLRSAATGGAALGPDTFKFFRAMGVPLRTLYGQTELLGAYTLHPDDKVDPDTTGVPMA
ADIEIRIDQPDSQGIGEILVRHPNMFLGYYKNLEASAADIKDGWMHSGDAGYFNDARQLVVIDRIKDLAETSRGERFSPQ
YIENKLKFSPYIAEAVVLGAGREHLAAMICIRYSIISKWAEKNRIAFTTYSDLASRNEVYALLQKEVETVNAHLPPAQRI
ARFLLLYKELDADDGELTRTRKVRRSVINEKYADIIDGIYGGKPAIPVDTVIRFQDGTTQRIRTTLKVVDLGGHGPMSEA
AE

Specific function: Could Catalyze The Transfer Of CoA To Crotonobetaine Or Carnitine. [C]

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI27477105, Length=614, Percent_Identity=25.5700325732899, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI83745141, Length=623, Percent_Identity=24.7191011235955, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI42794760, Length=566, Percent_Identity=26.8551236749117, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI42794758, Length=566, Percent_Identity=26.8551236749117, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI42794756, Length=566, Percent_Identity=26.8551236749117, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI40807491, Length=565, Percent_Identity=28.4955752212389, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI12669909, Length=612, Percent_Identity=24.8366013071895, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI4758332, Length=612, Percent_Identity=24.8366013071895, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI57165412, Length=591, Percent_Identity=26.0575296108291, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI57165410, Length=595, Percent_Identity=26.0504201680672, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI42794754, Length=606, Percent_Identity=24.2574257425743, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI42794752, Length=606, Percent_Identity=24.2574257425743, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1788107, Length=181, Percent_Identity=27.6243093922652, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17541856, Length=579, Percent_Identity=27.4611398963731, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17510401, Length=592, Percent_Identity=24.8310810810811, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25147511, Length=597, Percent_Identity=25.1256281407035, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17553312, Length=600, Percent_Identity=25.5, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17564090, Length=572, Percent_Identity=25.6993006993007, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17556552, Length=598, Percent_Identity=22.742474916388, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI193204819, Length=517, Percent_Identity=24.7582205029014, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI133901848, Length=217, Percent_Identity=27.1889400921659, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559526, Length=485, Percent_Identity=24.9484536082474, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320852, Length=634, Percent_Identity=22.2397476340694, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322182, Length=420, Percent_Identity=25.2380952380952, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323903, Length=363, Percent_Identity=26.1707988980716, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324893, Length=446, Percent_Identity=23.9910313901345, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319699, Length=417, Percent_Identity=24.220623501199, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17933690, Length=633, Percent_Identity=24.4865718799368, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI19921316, Length=620, Percent_Identity=26.6129032258064, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI281366413, Length=609, Percent_Identity=26.1083743842365, Blast_Score=182, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24666501, Length=609, Percent_Identity=26.1083743842365, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24666497, Length=609, Percent_Identity=26.1083743842365, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62471681, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI62471687, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24586634, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI22026970, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI62471679, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI62471683, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI62471685, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24586636, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI62471689, Length=596, Percent_Identity=22.9865771812081, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21355181, Length=462, Percent_Identity=23.1601731601732, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648257, Length=341, Percent_Identity=27.5659824046921, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 71843; Mature: 71843

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00626 RCC1_2 ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYARRVTQADTYPKLLRLNAKEHGQEIALREKDLGLWRTFTWADYQARVRDFALGMVDV
CCHHHHHHHCCCCHHHHCCCCHHCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHHEE
GLGKDDVIGIIGDNRPDWVAAEIATHAIRGHSLGLYRDVLDDEAAYLLNYGEARLVFAED
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHEECCCEEEEEECC
EEQVDKLLNLADRVPALKHIIYSDPRGMRKYDDPRLMPADKLAELGRARAAREPDLYDRM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
VDATVGDDVAILCTTSGTTSHPKLAMLSAARVLRHCANYLAFDPKGPEDEYVSVLPLPWI
HHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHH
MEQVYVLGKGLLCRMKVNFVEEPDTMMNDFREIAPTFVLFAPRVWEQIAADVRAAVMDAS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCH
PLKQRLYHIGMSAGLAALDKGQHSGFADMLLFRALRDRLGFTRLRSAATGGAALGPDTFK
HHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
FFRAMGVPLRTLYGQTELLGAYTLHPDDKVDPDTTGVPMAADIEIRIDQPDSQGIGEILV
HHHHHCCCHHHHCCCHHHEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHH
RHPNMFLGYYKNLEASAADIKDGWMHSGDAGYFNDARQLVVIDRIKDLAETSRGERFSPQ
HCCCHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHCCCCCCCHH
YIENKLKFSPYIAEAVVLGAGREHLAAMICIRYSIISKWAEKNRIAFTTYSDLASRNEVY
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCHHHHH
ALLQKEVETVNAHLPPAQRIARFLLLYKELDADDGELTRTRKVRRSVINEKYADIIDGIY
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GGKPAIPVDTVIRFQDGTTQRIRTTLKVVDLGGHGPMSEAAE
CCCCCCCHHHEEEECCCCHHHHHHEEEEEEECCCCCCHHCCC
>Mature Secondary Structure
MDYARRVTQADTYPKLLRLNAKEHGQEIALREKDLGLWRTFTWADYQARVRDFALGMVDV
CCHHHHHHHCCCCHHHHCCCCHHCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHHEE
GLGKDDVIGIIGDNRPDWVAAEIATHAIRGHSLGLYRDVLDDEAAYLLNYGEARLVFAED
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHEECCCEEEEEECC
EEQVDKLLNLADRVPALKHIIYSDPRGMRKYDDPRLMPADKLAELGRARAAREPDLYDRM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
VDATVGDDVAILCTTSGTTSHPKLAMLSAARVLRHCANYLAFDPKGPEDEYVSVLPLPWI
HHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHH
MEQVYVLGKGLLCRMKVNFVEEPDTMMNDFREIAPTFVLFAPRVWEQIAADVRAAVMDAS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCH
PLKQRLYHIGMSAGLAALDKGQHSGFADMLLFRALRDRLGFTRLRSAATGGAALGPDTFK
HHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
FFRAMGVPLRTLYGQTELLGAYTLHPDDKVDPDTTGVPMAADIEIRIDQPDSQGIGEILV
HHHHHCCCHHHHCCCHHHEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHH
RHPNMFLGYYKNLEASAADIKDGWMHSGDAGYFNDARQLVVIDRIKDLAETSRGERFSPQ
HCCCHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHCCCCCCCHH
YIENKLKFSPYIAEAVVLGAGREHLAAMICIRYSIISKWAEKNRIAFTTYSDLASRNEVY
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCHHHHH
ALLQKEVETVNAHLPPAQRIARFLLLYKELDADDGELTRTRKVRRSVINEKYADIIDGIY
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GGKPAIPVDTVIRFQDGTTQRIRTTLKVVDLGGHGPMSEAAE
CCCCCCCHHHEEEECCCCHHHHHHEEEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]