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The map label for this gene is fdsG [H]

Identifier: 146341845

GI number: 146341845

Start: 5168368

End: 5168844

Strand: Direct

Name: fdsG [H]

Synonym: BRADO4975

Alternate gene names: 146341845

Gene position: 5168368-5168844 (Clockwise)

Preceding gene: 146341842

Following gene: 146341846

Centisome position: 69.31

GC content: 66.88

Gene sequence:

>477_bases
ATGACGCCGGTGTACGAAAGTTGGGACGCGGCGCGCGGCGCCGAGATCATCGCCGAACATAGCCAGATGGAGGGAGCAAC
CTTGCCGATCCTCCACGCGTTGCAGGAGACGTTCGGTTATGTGCCCGAGGATGCCATTCCGATGATCGCATCCACCCTCA
ATCTGTCTCGCGCCGAGGTTTACGGCGTGTTCACGTTCTACCATGACTTCCGCGGCAAGAAGGCCGGCCGTCACGTGCTC
AAGCTGTGCCGTGCCGAGGCCTGCCAGGCCGCCGGCGGCGATGCGCTCGCGGCGCGCGCCGAGGCCAAGCTCGGGATTGC
GATGGGCAACACCACCGCCGACGAGCGCGTGACGCTCGAGCCGATCTACTGCCTCGGCCTGTGCGCGACCGCGCCGTCTG
CGATGATCGACGGCCGGCTGGTCGGCCGGCTCGATGAGGCCCGGATCGATGCTCTCGTCTCGGAGGCCCAGCGATGA

Upstream 100 bases:

>100_bases
GATTGCGTTTCGCTATCGCAGCACGGGACTGCTTTATTGATATCTTGAGCAATTCCAACTTGGATGTGCGAAACGCTTGC
AACGCAGAATTGGGATTAGA

Downstream 100 bases:

>100_bases
CGTTGCGTCTTTTTGTCCCGTGCGATGCTGGCGCGCTCGCCGTCGGCGCCGATGAGGTCGCCCACGCGCTGCACAAGGCG
GCGCTGGAGCGCAAGCTCGA

Product: formate dehydrogenase subunit gamma

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTPVYESWDAARGAEIIAEHSQMEGATLPILHALQETFGYVPEDAIPMIASTLNLSRAEVYGVFTFYHDFRGKKAGRHVL
KLCRAEACQAAGGDALAARAEAKLGIAMGNTTADERVTLEPIYCLGLCATAPSAMIDGRLVGRLDEARIDALVSEAQR

Sequences:

>Translated_158_residues
MTPVYESWDAARGAEIIAEHSQMEGATLPILHALQETFGYVPEDAIPMIASTLNLSRAEVYGVFTFYHDFRGKKAGRHVL
KLCRAEACQAAGGDALAARAEAKLGIAMGNTTADERVTLEPIYCLGLCATAPSAMIDGRLVGRLDEARIDALVSEAQR
>Mature_157_residues
TPVYESWDAARGAEIIAEHSQMEGATLPILHALQETFGYVPEDAIPMIASTLNLSRAEVYGVFTFYHDFRGKKAGRHVLK
LCRAEACQAAGGDALAARAEAKLGIAMGNTTADERVTLEPIYCLGLCATAPSAMIDGRLVGRLDEARIDALVSEAQR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=132, Percent_Identity=31.0606060606061, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788621, Length=112, Percent_Identity=40.1785714285714, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561328, Length=113, Percent_Identity=35.3982300884956, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859877, Length=121, Percent_Identity=33.0578512396694, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355353, Length=146, Percent_Identity=28.7671232876712, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 16982; Mature: 16850

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVYESWDAARGAEIIAEHSQMEGATLPILHALQETFGYVPEDAIPMIASTLNLSRAEV
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHH
YGVFTFYHDFRGKKAGRHVLKLCRAEACQAAGGDALAARAEAKLGIAMGNTTADERVTLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCCCEEEEC
PIYCLGLCATAPSAMIDGRLVGRLDEARIDALVSEAQR
HHHHHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPVYESWDAARGAEIIAEHSQMEGATLPILHALQETFGYVPEDAIPMIASTLNLSRAEV
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHH
YGVFTFYHDFRGKKAGRHVLKLCRAEACQAAGGDALAARAEAKLGIAMGNTTADERVTLE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCCCEEEEC
PIYCLGLCATAPSAMIDGRLVGRLDEARIDALVSEAQR
HHHHHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]