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The map label for this gene is 146341178

Identifier: 146341178

GI number: 146341178

Start: 4455785

End: 4457416

Strand: Reverse

Name: 146341178

Synonym: BRADO4251

Alternate gene names: NA

Gene position: 4457416-4455785 (Counterclockwise)

Preceding gene: 146341179

Following gene: 146341169

Centisome position: 59.78

GC content: 67.1

Gene sequence:

>1632_bases
ATGCATGCGCTGCGGTCCATCGCCGTCTTGCTGTGGGCGTTCTGGATCGGCTGCAGTGCCGCGCACGCCGAGCGGAAAGT
GGCGCTGGTCATCGGCAATTCCGCCTATCGGAATGTCGCCAAGCTCAAGAACCCTGTGAACGACGCGGCTCTCGTCGCGA
CGATGTTCAAGAACGCCGGCTTCGAGTCCGTTACCAGCCGGTTCGATCTCAACCTGAATGAGATGCGAAAGGCCCTCCGC
GAGTTCGGCGCCAAGGCCCGCGACGCACAGCTGGCCGTGATCTATTATGCCGGCCACGGCATCGAGCTCGACGGCACGAA
CTACCTGATTCCGACCGATGCGACGATCGAGAGCGATACCGACGTGCTGGACGAGGCGCTGTCGCTCGATCGGATGCTGG
TGGCCGTGGAGCCTGCCAAGCAGCTCAGGCTCGTCATTCTCGATGCCTGCCGCGACAATCCGTTCGCGAAGACGATGAAG
CGGACGATCGCGTCGCGATCGATCGGCCGAGGTCTCGCGAAGGTCGAGCCCAACGCACCGAACACGATGATCGCCTTCGC
GGCCAAGGCCGGATCGACAGCCGCCGACGGTGACGCGGCCAACAGTCCTTTTGCCCTCGCGATCACCGAGCATTTGCCGA
AGCCCGGGCTCGATCTCCGCAAGGCGTTCGGCTTCGTGCGCGACGACGTGCTGAAGAGCACCGGCAACAGGCAGGAGCCT
TATGTTTATGGCTCGCTCGGCGGCGACGACGTCTCGATCGTGCCGGCACCCGCCGCGCCGGTTGCCGCGCCGAACACGGC
GGACAACGCGCGCCGCGATTACGAGCTCGCGCTTCAAGCCAGCGACAAGGATGCCTGGGAGGCCTACCTCCAGCGCTATC
CAACCGGATTCTACGCCGACCTCGCGCGCGTGCAGCTGAGAAAGGCGGTCGCGGAGGAGACGCGGCTCAAGGCGGAGCGG
GCGAAGCCACAGGAGCCGGGACACGGCGAAGGTGAGAAGCCAATGGTTGTCGACGCCCGGGCGAGGGACGATGGTGGCTC
CGGCGAGAAGGTCGCCGCGCTCGCGATGCCGCCGGCTCGGCCGCCTTTCTCCGACTCCGAGCTCGCGACCTCGCTGCAGT
TGGAGTTGCGGCGGCTCGGCTGTCTCGATGCAGCTGTCAGTGGCGATCGGGATGCCGCCTCGGCGCGCGCGCTCGGCCAG
TTCAACGGCATCGCGCGCACCAGCTTCGAAACGGCGACGCCAAGCCTCGCCGCGCTCGATGCGCTCAAGGCGCGGAGTTC
CAGGATATGTCCGCTGTCATGCCAGTCGGGCTATCGCGTCGATGACGACAGCTGCGTGAAGATCGTGTGCCCAAGCAGTT
CGGAGCTGCGCCCGGACGGCAGCTGCGCGCGCAGCGAGAAGCCGGTTGCGAAGCGTGACAATGCGCGTCCCGAACCGGCG
CCGCGGCCCGCGCCGGCTGCGATCGATCTGAGCCGTCCCCAGCCCGGCGAGCCGCCGCCGGGCTCGCTGTCACTCGGCGC
CCGGGTGACCATTCAGAGCAGCGCCTGCGGTCCCGGGAAGGTGCTCGAACTGATCGGTGGCTCCAACCGCGCCAACATTC
CGCGGCAGCGGCGCTGCATCGCCGCTAACTGA

Upstream 100 bases:

>100_bases
GACAACGATATCCGACGTGATCCGTGTCACAGACCTTTCGACTGGCGTCTAATCATCTCCCGGCTATGCTGTTCTGCAAC
TGAATGTCGGGGGACATGGG

Downstream 100 bases:

>100_bases
ACACGCGCCTCGCACGGCTCAGGCGAACGCCTTCTCCACGGTCTCGATCAGCACCCGCAACGACTTGTCGTGGCGGGTGA
TCGGTGGGATCGCGCGGGTG

Product: hypothetical protein

Products: NA

Alternate protein names: Caspase Domain Protein; Caspase-Like Domain- And TPR Repeat-Containing Peptidase; Peptidase C; Caspase-Like Domain-Containing Protein; Peptidase Protein; Caspase Domain-Containing Protein; TPR Repeat-Containing Caspace; GUN4-Like Family; Caspase; Peptidylprolyl Isomerase; Caspase-1 P; ICE-Like Protease

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MHALRSIAVLLWAFWIGCSAAHAERKVALVIGNSAYRNVAKLKNPVNDAALVATMFKNAGFESVTSRFDLNLNEMRKALR
EFGAKARDAQLAVIYYAGHGIELDGTNYLIPTDATIESDTDVLDEALSLDRMLVAVEPAKQLRLVILDACRDNPFAKTMK
RTIASRSIGRGLAKVEPNAPNTMIAFAAKAGSTAADGDAANSPFALAITEHLPKPGLDLRKAFGFVRDDVLKSTGNRQEP
YVYGSLGGDDVSIVPAPAAPVAAPNTADNARRDYELALQASDKDAWEAYLQRYPTGFYADLARVQLRKAVAEETRLKAER
AKPQEPGHGEGEKPMVVDARARDDGGSGEKVAALAMPPARPPFSDSELATSLQLELRRLGCLDAAVSGDRDAASARALGQ
FNGIARTSFETATPSLAALDALKARSSRICPLSCQSGYRVDDDSCVKIVCPSSSELRPDGSCARSEKPVAKRDNARPEPA
PRPAPAAIDLSRPQPGEPPPGSLSLGARVTIQSSACGPGKVLELIGGSNRANIPRQRRCIAAN

Sequences:

>Translated_543_residues
MHALRSIAVLLWAFWIGCSAAHAERKVALVIGNSAYRNVAKLKNPVNDAALVATMFKNAGFESVTSRFDLNLNEMRKALR
EFGAKARDAQLAVIYYAGHGIELDGTNYLIPTDATIESDTDVLDEALSLDRMLVAVEPAKQLRLVILDACRDNPFAKTMK
RTIASRSIGRGLAKVEPNAPNTMIAFAAKAGSTAADGDAANSPFALAITEHLPKPGLDLRKAFGFVRDDVLKSTGNRQEP
YVYGSLGGDDVSIVPAPAAPVAAPNTADNARRDYELALQASDKDAWEAYLQRYPTGFYADLARVQLRKAVAEETRLKAER
AKPQEPGHGEGEKPMVVDARARDDGGSGEKVAALAMPPARPPFSDSELATSLQLELRRLGCLDAAVSGDRDAASARALGQ
FNGIARTSFETATPSLAALDALKARSSRICPLSCQSGYRVDDDSCVKIVCPSSSELRPDGSCARSEKPVAKRDNARPEPA
PRPAPAAIDLSRPQPGEPPPGSLSLGARVTIQSSACGPGKVLELIGGSNRANIPRQRRCIAAN
>Mature_543_residues
MHALRSIAVLLWAFWIGCSAAHAERKVALVIGNSAYRNVAKLKNPVNDAALVATMFKNAGFESVTSRFDLNLNEMRKALR
EFGAKARDAQLAVIYYAGHGIELDGTNYLIPTDATIESDTDVLDEALSLDRMLVAVEPAKQLRLVILDACRDNPFAKTMK
RTIASRSIGRGLAKVEPNAPNTMIAFAAKAGSTAADGDAANSPFALAITEHLPKPGLDLRKAFGFVRDDVLKSTGNRQEP
YVYGSLGGDDVSIVPAPAAPVAAPNTADNARRDYELALQASDKDAWEAYLQRYPTGFYADLARVQLRKAVAEETRLKAER
AKPQEPGHGEGEKPMVVDARARDDGGSGEKVAALAMPPARPPFSDSELATSLQLELRRLGCLDAAVSGDRDAASARALGQ
FNGIARTSFETATPSLAALDALKARSSRICPLSCQSGYRVDDDSCVKIVCPSSSELRPDGSCARSEKPVAKRDNARPEPA
PRPAPAAIDLSRPQPGEPPPGSLSLGARVTIQSSACGPGKVLELIGGSNRANIPRQRRCIAAN

Specific function: Unknown

COG id: COG4249

COG function: function code R; Uncharacterized protein containing caspase domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27886566, Length=130, Percent_Identity=34.6153846153846, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI5803078, Length=130, Percent_Identity=34.6153846153846, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25149817, Length=127, Percent_Identity=33.0708661417323, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 57861; Mature: 57861

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50208 CASPASE_P20

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHALRSIAVLLWAFWIGCSAAHAERKVALVIGNSAYRNVAKLKNPVNDAALVATMFKNAG
CHHHHHHHHHHHHHHHCCCHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCC
FESVTSRFDLNLNEMRKALREFGAKARDAQLAVIYYAGHGIELDGTNYLIPTDATIESDT
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEECCCCEEECCCCCCCCCH
DVLDEALSLDRMLVAVEPAKQLRLVILDACRDNPFAKTMKRTIASRSIGRGLAKVEPNAP
HHHHHHHHHHHEEEEECCHHHHEEHEEEHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCC
NTMIAFAAKAGSTAADGDAANSPFALAITEHLPKPGLDLRKAFGFVRDDVLKSTGNRQEP
CEEEEEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
YVYGSLGGDDVSIVPAPAAPVAAPNTADNARRDYELALQASDKDAWEAYLQRYPTGFYAD
EEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHH
LARVQLRKAVAEETRLKAERAKPQEPGHGEGEKPMVVDARARDDGGSGEKVAALAMPPAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCC
PPFSDSELATSLQLELRRLGCLDAAVSGDRDAASARALGQFNGIARTSFETATPSLAALD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALKARSSRICPLSCQSGYRVDDDSCVKIVCPSSSELRPDGSCARSEKPVAKRDNARPEPA
HHHHHCCCCCEEECCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCC
PRPAPAAIDLSRPQPGEPPPGSLSLGARVTIQSSACGPGKVLELIGGSNRANIPRQRRCI
CCCCCCEEECCCCCCCCCCCCCEECCEEEEEECCCCCCHHHHHHHCCCCCCCCCHHCCCC
AAN
CCC
>Mature Secondary Structure
MHALRSIAVLLWAFWIGCSAAHAERKVALVIGNSAYRNVAKLKNPVNDAALVATMFKNAG
CHHHHHHHHHHHHHHHCCCHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCC
FESVTSRFDLNLNEMRKALREFGAKARDAQLAVIYYAGHGIELDGTNYLIPTDATIESDT
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEECCCCEEECCCCCCCCCH
DVLDEALSLDRMLVAVEPAKQLRLVILDACRDNPFAKTMKRTIASRSIGRGLAKVEPNAP
HHHHHHHHHHHEEEEECCHHHHEEHEEEHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCC
NTMIAFAAKAGSTAADGDAANSPFALAITEHLPKPGLDLRKAFGFVRDDVLKSTGNRQEP
CEEEEEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
YVYGSLGGDDVSIVPAPAAPVAAPNTADNARRDYELALQASDKDAWEAYLQRYPTGFYAD
EEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHH
LARVQLRKAVAEETRLKAERAKPQEPGHGEGEKPMVVDARARDDGGSGEKVAALAMPPAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCC
PPFSDSELATSLQLELRRLGCLDAAVSGDRDAASARALGQFNGIARTSFETATPSLAALD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALKARSSRICPLSCQSGYRVDDDSCVKIVCPSSSELRPDGSCARSEKPVAKRDNARPEPA
HHHHHCCCCCEEECCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCC
PRPAPAAIDLSRPQPGEPPPGSLSLGARVTIQSSACGPGKVLELIGGSNRANIPRQRRCI
CCCCCCEEECCCCCCCCCCCCCEECCEEEEEECCCCCCHHHHHHHCCCCCCCCCHHCCCC
AAN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA