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The map label for this gene is nuoC [H]

Identifier: 146341113

GI number: 146341113

Start: 4386294

End: 4386899

Strand: Reverse

Name: nuoC [H]

Synonym: BRADO4184

Alternate gene names: 146341113

Gene position: 4386899-4386294 (Counterclockwise)

Preceding gene: 146341114

Following gene: 146341112

Centisome position: 58.83

GC content: 63.04

Gene sequence:

>606_bases
ATGGACGACGGCAGGCTCGACGCCCTTGGGCAGACGATCGTGAGCGCGCTTCCGGGCGCGGCGCTCGGCCACTCGGTCGC
CTTCAATCAGCTCACCGTGACCGTGGATCCTGCCCGGATCGTCGAGGTCGTCAAACATCTTCGTGACGATCCCGGCTGCC
GGTTCATCAACTTCACCGACATTACAGCGGTCGACTACCCGGAGCGCGCGAAGCGCTTCGAGGTGGTCTATCACTTCCTG
TCGCCGACGCTGAATACCCGCATCCGTCTCAAAGCCGAAGCCGACGAGATGACGCAGGTGCCGTCGATCATCGATGTCTT
TCCGGGCGCCGACTGGTTCGAGCGCGAGGCCTACGATCTCTATGGTGTGATCTTTGTCGGTCACCCCGACATGCGCCGGA
TCCTCACCGATTACGGCTTCGACGGCCATCCGCTGCGCAAGGACTTCCCGACGACCGGCTTCGTCGAGGTGCGCTACGAC
GACCAGGAGAAGCGGGTGATCTACGAGCCGGTGCGGCTCAACCAGGAATTCCGCAGGTTCGATTTCCTCTCGCCCTGGGA
AGGCGCGGACTATCCGCTGCCGGGCGATGAGAAGGCGACGAAGTGA

Upstream 100 bases:

>100_bases
CCGGCTGTCCGCCGACCGCGGAAGCGCTGCTGTACGGTGTTCTGCTGCTGCAGAAGAAGATCCGTCGCACCGGCACCATT
GAACGCTGAAGGTTTTCGCT

Downstream 100 bases:

>100_bases
ATGGGAGCGAAGGCATGAACGAGCAGAGCCCAGCACTCCGCAACTTCACGATCAATTTCGGTCCGCAGCATCCGGCGGCG
CACGGCGTGCTTCGTCTCGT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MDDGRLDALGQTIVSALPGAALGHSVAFNQLTVTVDPARIVEVVKHLRDDPGCRFINFTDITAVDYPERAKRFEVVYHFL
SPTLNTRIRLKAEADEMTQVPSIIDVFPGADWFEREAYDLYGVIFVGHPDMRRILTDYGFDGHPLRKDFPTTGFVEVRYD
DQEKRVIYEPVRLNQEFRRFDFLSPWEGADYPLPGDEKATK

Sequences:

>Translated_201_residues
MDDGRLDALGQTIVSALPGAALGHSVAFNQLTVTVDPARIVEVVKHLRDDPGCRFINFTDITAVDYPERAKRFEVVYHFL
SPTLNTRIRLKAEADEMTQVPSIIDVFPGADWFEREAYDLYGVIFVGHPDMRRILTDYGFDGHPLRKDFPTTGFVEVRYD
DQEKRVIYEPVRLNQEFRRFDFLSPWEGADYPLPGDEKATK
>Mature_201_residues
MDDGRLDALGQTIVSALPGAALGHSVAFNQLTVTVDPARIVEVVKHLRDDPGCRFINFTDITAVDYPERAKRFEVVYHFL
SPTLNTRIRLKAEADEMTQVPSIIDVFPGADWFEREAYDLYGVIFVGHPDMRRILTDYGFDGHPLRKDFPTTGFVEVRYD
DQEKRVIYEPVRLNQEFRRFDFLSPWEGADYPLPGDEKATK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=185, Percent_Identity=50.8108108108108, Blast_Score=202, Evalue=1e-52,
Organism=Escherichia coli, GI145693162, Length=127, Percent_Identity=37.007874015748, Blast_Score=84, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71990788, Length=184, Percent_Identity=47.2826086956522, Blast_Score=182, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI32563621, Length=184, Percent_Identity=47.2826086956522, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24656494, Length=185, Percent_Identity=48.1081081081081, Blast_Score=188, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 23042; Mature: 23042

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDGRLDALGQTIVSALPGAALGHSVAFNQLTVTVDPARIVEVVKHLRDDPGCRFINFTD
CCCCHHHHHHHHHHHHCCCCHHCCCEEEEEEEEEECHHHHHHHHHHHCCCCCCEEEEECC
ITAVDYPERAKRFEVVYHFLSPTLNTRIRLKAEADEMTQVPSIIDVFPGADWFEREAYDL
CEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHCCHHHHHCCCCCHHHCCCEEE
YGVIFVGHPDMRRILTDYGFDGHPLRKDFPTTGFVEVRYDDQEKRVIYEPVRLNQEFRRF
EEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECHHHCCHHHHHC
DFLSPWEGADYPLPGDEKATK
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDDGRLDALGQTIVSALPGAALGHSVAFNQLTVTVDPARIVEVVKHLRDDPGCRFINFTD
CCCCHHHHHHHHHHHHCCCCHHCCCEEEEEEEEEECHHHHHHHHHHHCCCCCCEEEEECC
ITAVDYPERAKRFEVVYHFLSPTLNTRIRLKAEADEMTQVPSIIDVFPGADWFEREAYDL
CEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHCCHHHHHCCCCCHHHCCCEEE
YGVIFVGHPDMRRILTDYGFDGHPLRKDFPTTGFVEVRYDDQEKRVIYEPVRLNQEFRRF
EEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECHHHCCHHHHHC
DFLSPWEGADYPLPGDEKATK
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA