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The map label for this gene is frr [H]

Identifier: 146341066

GI number: 146341066

Start: 4333470

End: 4334033

Strand: Reverse

Name: frr [H]

Synonym: BRADO4137

Alternate gene names: 146341066

Gene position: 4334033-4333470 (Counterclockwise)

Preceding gene: 146341067

Following gene: 146341065

Centisome position: 58.12

GC content: 65.96

Gene sequence:

>564_bases
ATGAGCACGGGCAATTTCGACCTCAACGAACTGAAGCGCCGCATGCAGGGCGCGACCCAGGCGCTGAAGCACGAGCTCGG
CGGCCTGCGCACCGGCCGCGCCTCGGCCTCGATGGTCGAGCCGGTGCAGGTCGAAGCGTATGGCTCGCACATGCCGCTCA
ACCAGCTCGCCACCGTCTCGGTGCCGGAGCCGCGCCTGCTCTCGGTGCAGGTGTGGGACCGCTCGATGGTCAAGGCCGTC
GAGAAGGCGATCGTCGATTCCAACCTCGGCCTGTCGCCGGCGACCGAAGGCCAGGTAATCCGGCTGCGCATTCCCGAGCT
CAACCAGGAGCGGCGCAAGGAGCTGGTCAAGGTCGCGCACAAATATGCCGAGCAGGCCCGCGTCGCCGTCCGTCACGTCC
GCCGCGACGGTCTCGATACGCTCAAGAAGCTCGAGAAGAATCACGAGATGTCCGAGGACGATCAGGAGCGGCTCGCCGGC
GACGTGCAGAAGGCGACCGACAGCGTGATCTCGGAGATCGACCAGCTGCTGGCGGCGAAGGAAAAGGAAATCCTCACCGT
CTGA

Upstream 100 bases:

>100_bases
CACAGGAATTCGTCCGGGCGCAATCAGGTCCAGCCGTCAGCCTCACATGGCCCGGCCAAACGGGCCGCGGAGCGCCGGGG
TTGCAGGAAAGGAAAGCGTG

Downstream 100 bases:

>100_bases
AGGATGCGCCTGATGTCCAAAGCCGCGGCCCCGGTGAAGGAAGCGCCGGACCGGTCCGACGCACCGGCCCATGTTGCCAT
TATCATGGATGGCAACGGCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSTGNFDLNELKRRMQGATQALKHELGGLRTGRASASMVEPVQVEAYGSHMPLNQLATVSVPEPRLLSVQVWDRSMVKAV
EKAIVDSNLGLSPATEGQVIRLRIPELNQERRKELVKVAHKYAEQARVAVRHVRRDGLDTLKKLEKNHEMSEDDQERLAG
DVQKATDSVISEIDQLLAAKEKEILTV

Sequences:

>Translated_187_residues
MSTGNFDLNELKRRMQGATQALKHELGGLRTGRASASMVEPVQVEAYGSHMPLNQLATVSVPEPRLLSVQVWDRSMVKAV
EKAIVDSNLGLSPATEGQVIRLRIPELNQERRKELVKVAHKYAEQARVAVRHVRRDGLDTLKKLEKNHEMSEDDQERLAG
DVQKATDSVISEIDQLLAAKEKEILTV
>Mature_186_residues
STGNFDLNELKRRMQGATQALKHELGGLRTGRASASMVEPVQVEAYGSHMPLNQLATVSVPEPRLLSVQVWDRSMVKAVE
KAIVDSNLGLSPATEGQVIRLRIPELNQERRKELVKVAHKYAEQARVAVRHVRRDGLDTLKKLEKNHEMSEDDQERLAGD
VQKATDSVISEIDQLLAAKEKEILTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=29.8342541436464, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI291042689, Length=182, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1786368, Length=172, Percent_Identity=50.5813953488372, Blast_Score=168, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24661488, Length=182, Percent_Identity=29.1208791208791, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20883; Mature: 20752

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGNFDLNELKRRMQGATQALKHELGGLRTGRASASMVEPVQVEAYGSHMPLNQLATVS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCCCCCHHHCEECC
VPEPRLLSVQVWDRSMVKAVEKAIVDSNLGLSPATEGQVIRLRIPELNQERRKELVKVAH
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYAEQARVAVRHVRRDGLDTLKKLEKNHEMSEDDQERLAGDVQKATDSVISEIDQLLAAK
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEILTV
HHHHCCC
>Mature Secondary Structure 
STGNFDLNELKRRMQGATQALKHELGGLRTGRASASMVEPVQVEAYGSHMPLNQLATVS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCCCCCHHHCEECC
VPEPRLLSVQVWDRSMVKAVEKAIVDSNLGLSPATEGQVIRLRIPELNQERRKELVKVAH
CCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYAEQARVAVRHVRRDGLDTLKKLEKNHEMSEDDQERLAGDVQKATDSVISEIDQLLAAK
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEILTV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA