Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 146341067

GI number: 146341067

Start: 4334197

End: 4334913

Strand: Reverse

Name: pyrH [H]

Synonym: BRADO4138

Alternate gene names: 146341067

Gene position: 4334913-4334197 (Counterclockwise)

Preceding gene: 146341068

Following gene: 146341066

Centisome position: 58.14

GC content: 67.92

Gene sequence:

>717_bases
ATGGCTGAGCCGGTCTATCGTCGCGTCGTGGTCAAGCTGTCCGGTGAGTATCTGGCAGGGCCCCATTCCTTCGGCATCGA
CCAGCCGACCGTGGACCGCATCGCGGACGATCTCATCGCAGTCCAGAAACTCGGCATCGAGATCGCCGTCGTCGTCGGCG
GCGGCAACATGGTGCGTGGCGTCGAGGTCTCGTCGCAGGGCGTCTCGCGTGCGACCGGCGACACCATGGGCATGCTGGCG
ACCGTCATGAACAGCCTGGCGCTGGAGGCGGCCTTGCAGCGCAAGGGAGCGCCGGCGGTCGCGTTGTCAGCCTTCGTGAT
GCCGCAGGTCTGCGAGCTGTTCACGCGTGCCGCGGCGCACAGGGCCCTCGCCGAGGGACGCATCGTCGTGCTCGGGGGCG
GCACCGGCAATCCCTACTTCACCACCGACACCACCGCCGTGCTGCGGGCCGCCGAGATCGGTGCGCAGGCCGTGCTGAAA
GCCACCAATGTCGATGGCGTCTACAGCGCGGATCCGAAGAAGGATCCGGCCGCCAAGCGCTTCGACCGGCTGACGCATTC
GCAGGCCATCGAGGGCGGCTACAAGGTGATGGATGCGACGGCGTTTGCGCTTGCCCGCGAAACGTCGCTGCCTATCATCG
TGTTCTCCATCGCCGAGCCCGGCGCCATCGGCGCGATGTTGCGGGGCGAAGGGCGGGGCACCATCGTCGCGGGGTGA

Upstream 100 bases:

>100_bases
TCGCCGCCGCCAGCGGCAAGAAGTAACGACTGACATCAGTCACGATCCGGCGCGGACGTCGCGCCGGATCTCAACGCGCG
AGATTGGGACATATTGGCAC

Downstream 100 bases:

>100_bases
GCCGCGGGACCGTCGGCGGCCGGTCTTGGACCGTTTCAACGGCTGCGGTAGAAGCGTAAGCGACACAGGAATTCGTCCGG
GCGCAATCAGGTCCAGCCGT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAEPVYRRVVVKLSGEYLAGPHSFGIDQPTVDRIADDLIAVQKLGIEIAVVVGGGNMVRGVEVSSQGVSRATGDTMGMLA
TVMNSLALEAALQRKGAPAVALSAFVMPQVCELFTRAAAHRALAEGRIVVLGGGTGNPYFTTDTTAVLRAAEIGAQAVLK
ATNVDGVYSADPKKDPAAKRFDRLTHSQAIEGGYKVMDATAFALARETSLPIIVFSIAEPGAIGAMLRGEGRGTIVAG

Sequences:

>Translated_238_residues
MAEPVYRRVVVKLSGEYLAGPHSFGIDQPTVDRIADDLIAVQKLGIEIAVVVGGGNMVRGVEVSSQGVSRATGDTMGMLA
TVMNSLALEAALQRKGAPAVALSAFVMPQVCELFTRAAAHRALAEGRIVVLGGGTGNPYFTTDTTAVLRAAEIGAQAVLK
ATNVDGVYSADPKKDPAAKRFDRLTHSQAIEGGYKVMDATAFALARETSLPIIVFSIAEPGAIGAMLRGEGRGTIVAG
>Mature_237_residues
AEPVYRRVVVKLSGEYLAGPHSFGIDQPTVDRIADDLIAVQKLGIEIAVVVGGGNMVRGVEVSSQGVSRATGDTMGMLAT
VMNSLALEAALQRKGAPAVALSAFVMPQVCELFTRAAAHRALAEGRIVVLGGGTGNPYFTTDTTAVLRAAEIGAQAVLKA
TNVDGVYSADPKKDPAAKRFDRLTHSQAIEGGYKVMDATAFALARETSLPIIVFSIAEPGAIGAMLRGEGRGTIVAG

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=235, Percent_Identity=48.936170212766, Blast_Score=234, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 24667; Mature: 24536

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPVYRRVVVKLSGEYLAGPHSFGIDQPTVDRIADDLIAVQKLGIEIAVVVGGGNMVRG
CCCHHHHHHHEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEE
VEVSSQGVSRATGDTMGMLATVMNSLALEAALQRKGAPAVALSAFVMPQVCELFTRAAAH
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RALAEGRIVVLGGGTGNPYFTTDTTAVLRAAEIGAQAVLKATNVDGVYSADPKKDPAAKR
HHHHCCCEEEEECCCCCCCEECCHHHHHHHHHHCHHHHHEECCCCCEECCCCCCCHHHHH
FDRLTHSQAIEGGYKVMDATAFALARETSLPIIVFSIAEPGAIGAMLRGEGRGTIVAG
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCEEEEEC
>Mature Secondary Structure 
AEPVYRRVVVKLSGEYLAGPHSFGIDQPTVDRIADDLIAVQKLGIEIAVVVGGGNMVRG
CCHHHHHHHEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEE
VEVSSQGVSRATGDTMGMLATVMNSLALEAALQRKGAPAVALSAFVMPQVCELFTRAAAH
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RALAEGRIVVLGGGTGNPYFTTDTTAVLRAAEIGAQAVLKATNVDGVYSADPKKDPAAKR
HHHHCCCEEEEECCCCCCCEECCHHHHHHHHHHCHHHHHEECCCCCEECCCCCCCHHHHH
FDRLTHSQAIEGGYKVMDATAFALARETSLPIIVFSIAEPGAIGAMLRGEGRGTIVAG
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA