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The map label for this gene is aprE [H]

Identifier: 146340900

GI number: 146340900

Start: 4152320

End: 4154254

Strand: Direct

Name: aprE [H]

Synonym: BRADO3967

Alternate gene names: 146340900

Gene position: 4152320-4154254 (Clockwise)

Preceding gene: 146340899

Following gene: 146340901

Centisome position: 55.69

GC content: 66.36

Gene sequence:

>1935_bases
ATGAAACACATCAACGACTTCAGGCCCTTCGATGACGACGACTATGTGCGACCGAAGACCCGTGCTGTCGGTCCCCAGGG
CGATGCGCTGATACTCGAGTTGCAGCGATTGCAGGGCGCCTTCGACGAGGGCTCGGACGAGGACCCGCGGGCACGTCGTG
GCGGCCGCGACGGCGGCAAGAAGCGGCGGCGTCCACCGCCGGCGCAGACGCGCGTCAAGCCGCGCAAGAAGAAGGGCAGC
ACCATGGGCCGCGCGCTCTCGCTGTTCGGACTCGGCGGCCAGGCTCAGCGGGAGCGTCATCGCGAGGGCATCCGCGAGAT
GGACTGGCAGAGGCCCGCGCCGGCGCGCGGACGCGAGCCGGAGCTGACACCGCCACCGCGCCATGCGCCTGCGCACATGC
CGAACAACAACAATATGCCTGTGCTCGACGTCCGAGAGGCACGTCGCGACGCCGGCTTCGGTGACGCGCCGCGACTGGGG
CAGCAGAACCTCCCTGCCCGCCTTGGTCAGGCGCCGGCCGTGCCGCAGACCGGCGTGCGCCGCCTCGTTGGAACCGCCAG
CACCGCGTTGACGACCGGCATGACGTTCATTGCGGCGCAGGGAACCGCGGCCGATCTCGACGATGATTCGGACGAGCAGC
TCGTTCCGCGCGTCGGCCGGATGTTCGAAAACGAATTGCGTCTCGGCCTGCGCGTCCTGCTGGTCGCGGCCGTGTTCGGC
GGCGGCTGGCTGACGCTGGTGCCGCTGGCCGGCGCAGTCGTCGTTCCCGGCAATCTCGTCGTGCAGTCCAACGTGAAGGC
CATCCAGCATCCGACCGGCGGCATCATCGCCGAGATCAAGGTCGACAACGGCAAGCGCGTCGCCGCCGGCGACCTGCTCG
TCCGGCTCGATGCGACGCAGAGCCAGGCGCAGCTGCAATCGATCACCAAGCAGCTCAACGAGCAGCGCGCCAAGATCGCG
CGCCTGTCGGCTGAGCGCGATGGTCTGGAGCAGCCGGAATACCCGGCCACGCTGACCTCACATACCGACGATCCGAACAT
TCGCGCCGTCATCGCATCGGAAAACGCGCTGTTCAAGGCCCGCGCGGTCACGCGCAAGAGCCAGAAGGAGCTGCTGCAGG
GACGCATCGTCCAGCTCAACAACGAGATCAGCGGCATGGAGGCGCAGCTCGATTCGAAGACCAAGCAGATCGACCTCATC
AAGGGCGAGCTTGCCGGCGTGCAGGATCTCTACGACAAGCGCCTCGTCCCGCTGACCCGGCTCACAACGCTGCAGCGGGA
AGCCGCGCGGATCGACGGCGAGCGCGGACAGCTGGTGTCGAGCGTCGCGGAAACGCGATCCAAGATCAGCGAGGCAGAGC
TGCAGACGGTCAAGATCGATCAGGACTTCCGCAGCGAGGTCGTCAAGGACCTCAGCGAGTCGCAGGCCAAGGAAGGCGAC
CTGGTGGAAAAGGGCGTGGCCGCACGCGACCAGCTGGACCGCATCGAGATGCGCGCGCCGAATTCGGGCACCATCCACCA
GCTCGCGGTTCACACCATCGGCGGCGTCATCAAGCCGGGCGAGACCATCATGGAGCTGGTGCCCGATTCGGACGAGCTGC
AGGTCGAAGGGCACGTTCAGCCCAAGGACATCGATCACGTCCACACCGGACAGGACGCGATGGTGCACTTCAATGCCTTC
AACTCGCACACGACGCCGAAGTTGAGCGGCCAGGTCTCGTTCGTCTCGCCGGATATTACCAACGACCAGCGCACGGGCTC
CACCTTCTACACGGTCAGGATCACGCTGCCGGATGAGGAGCGGAAGCGGCTCGGCGACGTCAATCTGAAGCCGGGCATGC
AGGCGGAGGTCTATGTCCAGACCGGCAGCCGGACGATGCTCAGCTACCTGATGAAGCCCGTTCTCGATCAGTGGCGCCGT
GCCTTCGTGGAGTAA

Upstream 100 bases:

>100_bases
TGCCGCGGCCGCTGCGCCCCGGGTCGCCGCTCCGGCAGCGGCCCCAAATCCGAACGCCAGAATGCTTCGTCGCGCCGCCC
CAGCAGAAAGCGCTTGATCA

Downstream 100 bases:

>100_bases
CAAGATCTGACATGTCACGGGCTGCGTCCGCAAGGGACGCAGACCGGCTCGGCCGATCAGCATGACGATTGCAAATTTTC
CCCGCGCCTCGGGCGCGACG

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MKHINDFRPFDDDDYVRPKTRAVGPQGDALILELQRLQGAFDEGSDEDPRARRGGRDGGKKRRRPPPAQTRVKPRKKKGS
TMGRALSLFGLGGQAQRERHREGIREMDWQRPAPARGREPELTPPPRHAPAHMPNNNNMPVLDVREARRDAGFGDAPRLG
QQNLPARLGQAPAVPQTGVRRLVGTASTALTTGMTFIAAQGTAADLDDDSDEQLVPRVGRMFENELRLGLRVLLVAAVFG
GGWLTLVPLAGAVVVPGNLVVQSNVKAIQHPTGGIIAEIKVDNGKRVAAGDLLVRLDATQSQAQLQSITKQLNEQRAKIA
RLSAERDGLEQPEYPATLTSHTDDPNIRAVIASENALFKARAVTRKSQKELLQGRIVQLNNEISGMEAQLDSKTKQIDLI
KGELAGVQDLYDKRLVPLTRLTTLQREAARIDGERGQLVSSVAETRSKISEAELQTVKIDQDFRSEVVKDLSESQAKEGD
LVEKGVAARDQLDRIEMRAPNSGTIHQLAVHTIGGVIKPGETIMELVPDSDELQVEGHVQPKDIDHVHTGQDAMVHFNAF
NSHTTPKLSGQVSFVSPDITNDQRTGSTFYTVRITLPDEERKRLGDVNLKPGMQAEVYVQTGSRTMLSYLMKPVLDQWRR
AFVE

Sequences:

>Translated_644_residues
MKHINDFRPFDDDDYVRPKTRAVGPQGDALILELQRLQGAFDEGSDEDPRARRGGRDGGKKRRRPPPAQTRVKPRKKKGS
TMGRALSLFGLGGQAQRERHREGIREMDWQRPAPARGREPELTPPPRHAPAHMPNNNNMPVLDVREARRDAGFGDAPRLG
QQNLPARLGQAPAVPQTGVRRLVGTASTALTTGMTFIAAQGTAADLDDDSDEQLVPRVGRMFENELRLGLRVLLVAAVFG
GGWLTLVPLAGAVVVPGNLVVQSNVKAIQHPTGGIIAEIKVDNGKRVAAGDLLVRLDATQSQAQLQSITKQLNEQRAKIA
RLSAERDGLEQPEYPATLTSHTDDPNIRAVIASENALFKARAVTRKSQKELLQGRIVQLNNEISGMEAQLDSKTKQIDLI
KGELAGVQDLYDKRLVPLTRLTTLQREAARIDGERGQLVSSVAETRSKISEAELQTVKIDQDFRSEVVKDLSESQAKEGD
LVEKGVAARDQLDRIEMRAPNSGTIHQLAVHTIGGVIKPGETIMELVPDSDELQVEGHVQPKDIDHVHTGQDAMVHFNAF
NSHTTPKLSGQVSFVSPDITNDQRTGSTFYTVRITLPDEERKRLGDVNLKPGMQAEVYVQTGSRTMLSYLMKPVLDQWRR
AFVE
>Mature_644_residues
MKHINDFRPFDDDDYVRPKTRAVGPQGDALILELQRLQGAFDEGSDEDPRARRGGRDGGKKRRRPPPAQTRVKPRKKKGS
TMGRALSLFGLGGQAQRERHREGIREMDWQRPAPARGREPELTPPPRHAPAHMPNNNNMPVLDVREARRDAGFGDAPRLG
QQNLPARLGQAPAVPQTGVRRLVGTASTALTTGMTFIAAQGTAADLDDDSDEQLVPRVGRMFENELRLGLRVLLVAAVFG
GGWLTLVPLAGAVVVPGNLVVQSNVKAIQHPTGGIIAEIKVDNGKRVAAGDLLVRLDATQSQAQLQSITKQLNEQRAKIA
RLSAERDGLEQPEYPATLTSHTDDPNIRAVIASENALFKARAVTRKSQKELLQGRIVQLNNEISGMEAQLDSKTKQIDLI
KGELAGVQDLYDKRLVPLTRLTTLQREAARIDGERGQLVSSVAETRSKISEAELQTVKIDQDFRSEVVKDLSESQAKEGD
LVEKGVAARDQLDRIEMRAPNSGTIHQLAVHTIGGVIKPGETIMELVPDSDELQVEGHVQPKDIDHVHTGQDAMVHFNAF
NSHTTPKLSGQVSFVSPDITNDQRTGSTFYTVRITLPDEERKRLGDVNLKPGMQAEVYVQTGSRTMLSYLMKPVLDQWRR
AFVE

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 70901; Mature: 70901

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHINDFRPFDDDDYVRPKTRAVGPQGDALILELQRLQGAFDEGSDEDPRARRGGRDGGK
CCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEEHHHHHCCCCCCCCCCCHHHCCCCCCCC
KRRRPPPAQTRVKPRKKKGSTMGRALSLFGLGGQAQRERHREGIREMDWQRPAPARGREP
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
ELTPPPRHAPAHMPNNNNMPVLDVREARRDAGFGDAPRLGQQNLPARLGQAPAVPQTGVR
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHH
RLVGTASTALTTGMTFIAAQGTAADLDDDSDEQLVPRVGRMFENELRLGLRVLLVAAVFG
HHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGWLTLVPLAGAVVVPGNLVVQSNVKAIQHPTGGIIAEIKVDNGKRVAAGDLLVRLDATQ
CCCEEEEHHCCEEEECCCEEEECCCHHHCCCCCCEEEEEEECCCCEEEECCEEEEECCCH
SQAQLQSITKQLNEQRAKIARLSAERDGLEQPEYPATLTSHTDDPNIRAVIASENALFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEEECCCCHHHH
RAVTRKSQKELLQGRIVQLNNEISGMEAQLDSKTKQIDLIKGELAGVQDLYDKRLVPLTR
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHCCCHHEEEEHHHHHHHHHHHHHCCCCCHHH
LTTLQREAARIDGERGQLVSSVAETRSKISEAELQTVKIDQDFRSEVVKDLSESQAKEGD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHCCCCC
LVEKGVAARDQLDRIEMRAPNSGTIHQLAVHTIGGVIKPGETIMELVPDSDELQVEGHVQ
HHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCC
PKDIDHVHTGQDAMVHFNAFNSHTTPKLSGQVSFVSPDITNDQRTGSTFYTVRITLPDEE
CCCCCCEECCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCHH
RKRLGDVNLKPGMQAEVYVQTGSRTMLSYLMKPVLDQWRRAFVE
HHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHINDFRPFDDDDYVRPKTRAVGPQGDALILELQRLQGAFDEGSDEDPRARRGGRDGGK
CCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEEHHHHHCCCCCCCCCCCHHHCCCCCCCC
KRRRPPPAQTRVKPRKKKGSTMGRALSLFGLGGQAQRERHREGIREMDWQRPAPARGREP
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
ELTPPPRHAPAHMPNNNNMPVLDVREARRDAGFGDAPRLGQQNLPARLGQAPAVPQTGVR
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHH
RLVGTASTALTTGMTFIAAQGTAADLDDDSDEQLVPRVGRMFENELRLGLRVLLVAAVFG
HHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGWLTLVPLAGAVVVPGNLVVQSNVKAIQHPTGGIIAEIKVDNGKRVAAGDLLVRLDATQ
CCCEEEEHHCCEEEECCCEEEECCCHHHCCCCCCEEEEEEECCCCEEEECCEEEEECCCH
SQAQLQSITKQLNEQRAKIARLSAERDGLEQPEYPATLTSHTDDPNIRAVIASENALFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEEECCCCHHHH
RAVTRKSQKELLQGRIVQLNNEISGMEAQLDSKTKQIDLIKGELAGVQDLYDKRLVPLTR
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHCCCHHEEEEHHHHHHHHHHHHHCCCCCHHH
LTTLQREAARIDGERGQLVSSVAETRSKISEAELQTVKIDQDFRSEVVKDLSESQAKEGD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHCCCCC
LVEKGVAARDQLDRIEMRAPNSGTIHQLAVHTIGGVIKPGETIMELVPDSDELQVEGHVQ
HHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCC
PKDIDHVHTGQDAMVHFNAFNSHTTPKLSGQVSFVSPDITNDQRTGSTFYTVRITLPDEE
CCCCCCEECCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCHH
RKRLGDVNLKPGMQAEVYVQTGSRTMLSYLMKPVLDQWRRAFVE
HHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]